Researchers:

Jane English, John F Cryan, Olivia O’Leary, Maria R. Aburto.

• Molecular underpinnings of stress resilience.
• Molecular underpinnings of antidepressant action.
• Large scale study of proteins in human post-mortem brain tissue, stem cells, plasma, serum, CSF, and animal models of neuropsychiatric disease.
• Elucidating the molecular mechanisms underlying neurodevelopmental and psychiatric disorders.
• Protein expression profiling of anatomical sub-regions and sub-proteomes (e.g. mem-brane proteins, myelin proteins, synaptic proteins) in human post-mortem brain.
• Proteomics and integrative-omics analyses to unravel disease complexity and pinpoint novel therapeutic targets.
• Applying novel mass spectrometry approaches for the identification of blood based biomarkers to predict the onset of neurodevelopmental & neuropsychiatric disorders, and facilitate early intervention.
• Bioinformatic