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June 2014
June 2014
June 2014: Cresyl violet (nissl stain) image of the hippocampus from a mouse model of Temporal Lobe Epilepsy
Submitted by Elaine O’Loughlan Department of Anatomy & Neuroscience
Image shows severe hippocampal sclerosis: ablation of CA1 and CA3 sublayers and also disorganisation of the granule cell layer otherwise known as "granule cell dispersion". This is one of the most prominent pathological hallmarks of Temporal Lobe Epilepsy.
Elaine is a PhD student under the supervision of Dr. Keiran McDermott and Dr Deniz Yilmazer-Hanke (external co-supervisor) her research interests include: cellular and cyotarchitectural changes that occur in the amygdala in temporal lobe epilepsy and the implications for co-morbidity factors.
Image taken on Olympus AX70 Provis Brightfield microscope.