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April 2014
April 2014
April 2014: Au Coeur de la Cellule
Image submitted by Dr André Toulouse, Department of Anatomy & Neuroscience UCC
Heart-shaped protein aggregates at the periphery of the nucleus of a cell.
Polyglutamine diseases are a group of neurological movement disorders including Huntington’s disease and several spinocerebellar ataxias. We created a cellular model to study abnormal protein production in these diseases and while characterizing the cells under fluorescence microscopy, we observed this heart-shaped protein inclusion at the periphery of a nucleus.
“Au Coeur de la Cellule” was recently on display in the Jennings Gallery, as part of the “It’s a Beautiful World” Exhibition.