2016
UCC Physiology in fine fettle at national conference
The Department of Physiology hosted the Annual Meeting of the Section of Biomedical Sciences of the Royal Academy of Medicine in Ireland on Thursday 21st June 2016 at the Western Gateway Building, University College Cork.
The national conference included work from researchers at Trinity College Dublin, University College Cork, NUI Galway, University College Dublin, Dundalk Institute of Technology and the Royal College of Surgeons in Ireland, showcasing an impressive array of biomedical science conducted by up-and-coming talented trainees.
UCC Physiology was well represented at the meeting with oral and poster communications from undergraduate BSc Physiology students, MSc and PhD trainees, and post-doctoral researchers. Kevin Barry-Murphy (O’Malley lab), Conor Slattery (O’Malley lab), Kevin Murphy (O’Halloran lab) and Karen O’Connor (O’Halloran & Cryan labs; APC) competed for the Donegan Medal delivering oral communications. PhD trainees David Burns (O’Halloran lab) and Aidan Karr (Rae lab) presented oral communications. Dr. Julie O’Neill competed in the Barcroft Medal Competition for early career scientists with an oral communication of her work. Several other exciting projects were on display as poster communications (see below).
Following the exciting meeting, researchers dined at the Lewis Glucksman Gallery, UCC. Professor Ken O’Halloran (General Secretary, RAMI) presented prize winners with their awards, congratulated all presenters for their outstanding work, and concluded with the positive outlook that each trainee had served as able ambassador for their respective institutions, showcasing their talents and the high calibre biomedical science that is performed the length and breadth of the country.
It is rumoured that the group retired to a Barrack Street watering hole following dinner to contemplate further the successes of the day!
Oral Communications by UCC Physiology
GHRELIN DOES NOT SENSITISE COLONIC MYENTERIC NEURONS TO GLP-1 IN SPRAGUE-DAWLEY RATS
R. O’Brien1 , K. Barry Murphy1 and D. O’Malley1,2
1Department of Physiology and 2APC Microbiome Institute, Biosciences Institute, University College Cork, Cork, Ireland.
RESTORATION OF PHARYNGEAL DILATOR MUSCLE FORCE IN DYSTROPHIN DEFICIENT (MDX) MICE FOLLOWING CO-TREATMENT WITH NEUTRALIZING IL-6R ANTIBODY AND UROCORTIN-2
K. Murphy1 , D.P. Burns1 , J. Rowland2 , L. Canavan2 , D. O'Malley1 , K.D. O’ Halloran1 and D. Edge2 1Department of Physiology, School of Medicine, University College Cork, Cork, Ireland; 2Physiology, Trinity Biomedical Sciences Institute, Trinity College Dublin, the University of Dublin, Dublin, Ireland.
MICROBIOTA AND RESPIRATORY CONTROL: BLUNTED VENTILATORY RESPONSIVENESS TO HYPERCAPNIA IN ADULT MALE RATS FOLLOWING CHRONIC ANTIBIOTIC TREATMENT
K.M. O’Connor1,2,3, D.P. Burns1 , E.F. Lucking1 , A.V. Golubeva3 , J.F. Cryan2,3 and K.D. O’Halloran1,3 Departments of 1Physiology and 2Anatomy and Neuroscience, School of Medicine, and 3APC Microbiome Institute, University College Cork, Cork, Ireland.
THE BACTERIAL METABOLITE INDOLE SIGNALS TO THE CNS USING L-CELLS TO ACTIVATE VAGAL NERVE ACTIVITY
M.M. Buckley1,2 , C. Slattery1 and D. O’Malley1,2
1Department of Physiology and 2APC Microbiome Institute, Biosciences Institute, University College Cork, Cork, Ireland.
CAROTID BODY DYSFUNCTION AND HYPOVENTILATION IN THE DYSTROPHIN DEFICIENT MDX MOUSE
D.P. Burns1 , A. Roy2 , J. Rowland3 , E.F. Lucking1 , F.B. McDonald2 , D. Edge3 , R. Wilson2 , K.D. O’Halloran1 1Department of Physiology, School of Medicine, University College Cork, Cork, Ireland; 2Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; 3Department of Physiology, Trinity Biomedical Sciences Institute, Trinity College Dublin, the University of Dublin, Dublin, Ireland.
CALCIUM DYSREGULATION IN CULTURED HIPPOCAMPAL NEURONES FROM YOUNG RODENT MODELS OF ALZHEIMER’S DISEASE (3xTg-AD MOUSE & TgF344-AD RAT)
A. Kaar and M.G. Rae Department of Physiology, University College Cork, Cork, Ireland.
RENAL OXYGEN HOMEOSTASIS IS PERTURBED FOLLOWING EXPOSURE TO LONG-TERM BUT NOT SHORT-TERM INTERMITTENT HYPOXIA IN ANAESTHETIZED RATS
J. O’Neill, O. Brett, E.F. Lucking, M. Abdullah, G. Jasionek, K. McDonnell, K.D. O’Halloran Department of Physiology, School of Medicine, University College Cork, Cork, Ireland.
Poster Communications by UCC Physiology
THE MAS RECEPTOR DOES NOT MODULATE GROUP I METABOTROPIC GLUTAMATE RECEPTOR-MEDIATED CALCIUM SIGNALS IN MOUSE HIPPOCAMPAL NEURONS
A. Brett, A. Kaar and M.G. Rae
Department of Physiology, University College Cork, Cork, Ireland.
MICROBIOTA AND CARDIORESPIRATORY CONTROL: CHRONIC ANTIBIOTIC TREATMENT DOES NOT ALTER CARDIOVASCULAR REFLEX RESPONSE TO CHEMOSTIMULATION IN URETHANE ANESTHETISED RATS
E.F. Lucking1 , K.M. O’Connor1,2,4, D.P. Burns1 , A.V. Golubeva4 , T. Walther3 , J.F. Cryan2,4 and K.D. O’Halloran1,4
Departments of 1Physiology, 2Anatomy and Neuroscience, 3Pharmacology & Therapeutics, School of Medicine, and 4APC Microbiome Institute, University College Cork, Cork, Ireland.
ACUTE HYPOXIC STRESS CAUSES DIAPHRAGM WEAKNESS IN MICE AND RATS
A.J. O’Leary, C. Rieux, L. Browne and K.D. O’Halloran
Department of Physiology, School of Medicine, University College Cork, Cork, Ireland.
CHRONIC TEMPOL SUPPLEMENTATION RESTORES DIAPHRAGM MUSCLE FORCE-GENERATING CAPACITY IN THE DYSTROPHIN DEFICIENT MDX MOUSE
D.P. Burns1 , C. Rieux1 , I. Ali1 , J. Healy1 , D. Edge2 and K.D. O’Halloran1
1Department of Physiology, School of Medicine, University College Cork, Cork, Ireland; 2Physiology, Trinity Biomedical Sciences Institute, Trinity College Dublin, the University of Dublin, Dublin, Ireland.
EFFECTS OF AEROBIC EXERCISE ON QUALITY OF LIFE, DEPRESSION AND COGNITION IN PATIENTS WITH MULTIPLE SCLEROSIS
A. Barry1 , O. Cronin2 , A.P. Allen3 , G. Clarke3 , O. O’Toole4 , S.M. Yap4 , B. Sweeney5 , A.M. Ryan5 , K.D. O’ Halloran1 , E.J. Downer6
1Department of Physiology, School of Medicine, University College Cork, Cork, Ireland; 2Department of Medicine, Cork University Hospital, Cork, Ireland; 3Department of Psychiatry & Neurobehavioral Science, APC Microbiome Institute, University College Cork, Cork, Ireland; 4Mercy University Hospital, Cork, Ireland; 5Department of Neurology, Cork University Hospital, Cork, Ireland; 6Department of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland.
EFFECTS OF CHRONIC INTERMITTENT HYPOXIA ON BREATHING, METABOLISM AND DIAPHRAGM CONTRACTILE PROPERTIES IN ADULT MALE MICE
S. Drummond, D.P. Burns, K.D. O’Halloran
Department of Physiology, School of Medicine, University College Cork, Cork, Ireland.
PHYSIOLOGY—THE MUSIC OF LIFE
K.D. O’Halloran
Department of Physiology, School of Medicine, University College Cork, Cork, Ireland.