Research achievements of the Biophysics and Bioanalysis Lab

The Biophysics and Bioanalysis has successfully advanced its research projects, particularly the SFI and IPIC (Irish Photonics Integration Research Centre) projects in the area of Biophotonics and sensors.

The work has produced a number of significant research outcomes in the last 3-4 months, including:

• Three primary papers published in high impact journals CMLS (IF 9.2) and Sensors & Actuators Part B (IF 7.4) – see their details below. 
  Two additional research papers have also been submitted to Bioconjugate Chemistry (led by Chiara Zanetti) and JoVE (led by Rajannya Sen) journals, and three other are being prepared for submission.
• Three conference presentations including two posters and one invited oral talk – see below. In addition, Chiara Zanetti, Liang Li and Dr Rafael Gaspar (Sparkle Fellow) participated in the IPIC Industry Day in May 2022 with poster presentations.

During May-August 2022, our lab:

Published three papers in high impact journals (CMLS – 9.2; SNB – 7.3): 

1. Zhdanov AV, Golubeva AV, Yordanova MM, Andreev DE, Schellekens H, Baranov PV, Cryan JF, Papkovsky DB, Ghrelin rapidly elevates protein synthesis by employing the rpS6K-eEF2K-eEF2 signalling axis, CMLS, 2022, 79 (8), 1-20. DOI: 10.1007/s00018-022-04446-4.  
2. Sen Rajannya, Li Liang, Zhdanov Alex, Gaspar Rafael, Papkovsky DB, Phosphorescence lifetime measurements with sensor materials: comparison of the four different detection platforms, Sens Actuat B., 2022, 132496. https://doi.org/10.1016/j.snb.2022.132496
3. Li Liang, Zhdanov Alex, Papkovsky Dmitri, Advanced multimodal solid-state optochemical pH and dual pH/O2 sensors for cell analysis, Sens Actuat B., 2022, 132486. https://doi.org/10.1016/j.snb.2022.132486 
    

Attended the 7th International Conference on Molecular Sensors and Logic Gates:

1. Dr Rafael Gaspar – invited oral Talk ‘New hydrophilic phosphorescent porphyrin labels with nitriloacetic moiety for protein labelling’  
2. Chiara Zanetti, PhD3 – poster ‘Hetero-substituted derivatives of PtPFPP for O2 sensing and cell analysis’
3. Liang Li, PhD2 – poster ‘Multimodal pH and dual pH/oxygen sensors for live cell analysis’