Current research interests include the neurobiological basis of stress-related neuropsychiatric disorders including depression, anxiety and drug dependence. Moreover, his group is also focused on understanding the interaction between brain and gut and how it applies to stress and immune-related disorders, including irritable bowel syndrome, obesity and sepsis. He is also interested in applying novel approaches to facilitate drug/siRNA delivery to the brain in vivo.

Dr. Cryan's research group iand consists of 4 Postdoctoral Fellows, 14 PhD students, 1 MSc Students, 3 research scientists and various visiting students from Ireland, Spain, The Netherlands, USA & Canada. It is funded by Science Foundation Ireland, the Health Research Board, Enterprise Ireland and the Irish Research Council for Science, Engineering and Technology. Moreover, Dr. Cryan receives funding as a Pi on the EU Framework 7 Programme grant "Devanx" focused on  understanding the role of brain serotonin and GABAB receptors in anxiety: from developmental risk factors to treatment (

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