Completed Research

 

 

Completed Projects 
Autism    The AUTISM study aims to develop a neonatal screening test for early detection of Autism Spectrum Disorder (ASD)  
Baseline   BASELINE stands for Babies After SCOPE,  BASELINE is providing detailed information on maternal health, foetal growth, childhood nutrition, growth and development in the first 5 years of life. It includes a number of nutrition-led strands, focused around biomarkers of diet and nutritional status and growth during pregnancy and early infancy as a predictor of early health outcomes
BabyLink   BabyLink is a collaboration with IBM to develop a remote monitoring solution for the newborn brain.  The progress made by INFANT researchers since the project's launch has seen BabyLink applied in a multi-bed single unit NICU environment. It transmits EEG signals to a cloud-based server where algorithms analyse the data as it arrives and provide real-time interpretation of neurological signals. 
BEYOND BiHiVE   BEYOND BiHiVE is the next stage of the BiHiVE project, which investigates blood biomarkers. BEYOND BiHiVE can be seen as part of the BiHiVE2 study. It also focuses on inflammatory markers, and will target the markers with the most potential for a bedside diagnostic test. Once the findings of BEYOND BiHiVE are validated, researchers will move on to developing the bedside algorithm, which will provide a point-of-care diagnosis for HIE. 
CARE   Children with physical and intellectual disabilities make up 6.7% of the Irish population and require extra supportive care and services daily, for them to participate in all aspects of life. The imposed COVID-19 restrictions will have reduced or removed their support network, which will directly impact the physical and mental development of these children. The current situation will also inevitably impact the well-being of carers and affect the quality of life for both entities.  CARE is an anonymous online survey study, designed to evaluate the impact of COVID-19 restrictions on accessibility of support services for carers of child(ren) with special needs, and the effect, if any, on carer well-being.
Delphi   The Delphi project will develop a smart brain monitoring system for newborns that may have brain injury. The new system will help to detect the severity of brain damage as soon as possible enabling early intervention and appropriate therapies tailored to each individual baby.
Enrich   The ENRICH study aims to understand the effects of lifestyles, sensory experiences and sleep patterns on the cognitive development of healthy infants.
HiP   HiP (Management of Hypotension In the Preterm Infant) is an international, multi-centre, randomised control clinical trial involving dopamine versus placebo.The HiP study recruits extremely preterm infants (born at less than 28 weeks). The study is an exploration of the management of hypotension in the preterm infant. 
NEUROPROBE  

The NEUROPROBE study will develop cot-side devices which continuously assess brain health in preterm infants.

These innovative devices will analyse factors like brain electrical activity, oxygen levels and blood pressure. This data will be interpreted by algorithms which INFANT researchers have designed, to provide clinicians with an index of brain health for preterm infants. The ultimate goal is to achieve better standards of care in managing preterm babies in neonatal intensive care units worldwide.

 
Nested   NESTED is a project which will develop, test and train an algorithm which can detect seizures in premature babies in the Neonatal Intensive Care Unit (NICU). It follows on from the ANSeR project, which focused on full-term babies. With NESTED, our researchers aim to develop a robust, reliable, automated seizure detection system for the detection of seizures in preterm neonates and facilitate prompt treatment. 
PiNPoINT   PiNPoINT (Personalised Nutrition for the Preterm Infant) aims to develop a nutritional strategy for preterm infants with a very low birth weight. Using real-time nutritional data collection and mointoring, INFANT researchers will address the knowledge gaps in nutritional requirements where very low birth weight infants are concerned.
Stop AD   The SKIN Study is a range finding pilot study which is needed to establish the range of NMF and TEWL values in a healthy neonatal population. These data will be used to inform the STOP AD intervention trial, which will investigate the effect of early skin barrier protection on the prevention of eczema and food allergy in high risk children.

Department of Paediatrics & Child Health

Péidiatraic agus Sláinte Leanaí

Floor 2, Paediatric Unit, Cork University Hospital, Wilton, Cork, T12 DC4A

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