Staff Research Interests

Staff Member	Research Interests
Dr Evin Allen Pharmaceutics	Biopharmaceutical Drug product manufacture Single Use Technology Container Closure Integrity Freeze Drying Filling processes Education of the (bio)pharmaceutical sector Knowledge Management
Dr Teresa Barbosa Clinical Pharmacy	Infectious disease Antimicrobials, antimicrobial resistance and stewardship Long term impact of antimicrobial Education and training on antimicrobials and
Dr Lorraine Bateman Pharmaceutical Chemistry	Nuclear Magnetic Resonance (NMR) Spectroscopy as a key technique for Pharmaceutical synthesis and analysis Pharmaceutical Chemistry Process; in situ reaction monitoring Advanced structure and mechanism elucidation Dynamic systems, systems in equilibrium
Dr Harriet Bennett-Lenane Clinical Pharmaceutics	Machine Learning-Informed Medicines Optimisation. Computational Pharmaceutics-informed Drug Delivery. Digitalisation of Pharmacy Practice. Delivery of Community Pharmacy Services to Vulnerable Patient Groups. Career Pathways and Motivators of Pharmacy Students and Graduates.
Dr Margaret Bermingham Clinical Pharmacy	Prevention and treatment of chronic disease with a focus on cardiovascular disease and diabetes Chronic disease and medicines management in primary and secondary care Biosimilar medicines
Prof Stephen Byrne Clinical Pharmacy	The use of screening tools to aid in the identification of inappropriately prescribed medicines in a primary and secondary care setting Enhancing the role of the community and hospital pharmacists in monitoring and optimising prescribing The Use of the Behavioural Change Wheel to enhance pharmacists interventions Pharmacoeconomics and Pharmacoepidemiology
Prof Abina Crean Pharmaceutics	Development of formulation approaches to enhance the oral bioavailability of drug molecules challenged by poor-water solubility Formulation and characterisation of microneedle drug delivery systems Investigating critical attributes of drugs and excipients that impact on the processing and performance of drug products Biophysical characterisation, processing and formulation of peptide, protein and vaccine therapeutics and medical devices
Dr Kieran Dalton Clinical Pharmacy	Pharmacist prescribing in hospital settings Prescribing optimisation in older adults Role of pharmacists in general practice settings Communication between healthcare professionals Pharmacy education research and interprofessional learning
Dr Maria Donovan Clinical Pharmacy	Pharmacokinetic modelling Technology-enhanced learning in healthcare Experiential learning Deprescribing in community pharmacy
Dr Aoife Fleming Clinical Pharmacy	Antimicrobial Stewardship Infection biomarkers (C reactive protein, procalcitonin) Vaccinations: role of the healthcare professional & hesitancy Prescribing and medication management in long term care facilities Medication safety and reconciliation Behaviour Change interventions
Dr Eoin Fleming Biochemistry	Diseases of protein misfolding Inflammation Cancer
Prof Cormac Gahan Microbiology	Functional Metagenomics of the GI tract Host-Pathogen interactions in the GI tract Development of Novel Vaccines Bactofection & DNA Delivery
Prof Brendan Griffin Pharmaceutics	Targeted drug delivery Oral drug delivery systems Nano drug delivery
Dr J J Keating Pharmaceutical Chemistry	Impurity profiling on amphetamine-type drugs of abuse Independent synthesis of impurities arising from synthetic routes to amphetamine analogues Synthetic and biological activity of compounds which increase brain serotonin levels
Dr Piotr Kowalski Pharmaceutics	nanotechnology nucleic acid delivery biomaterials engineering gene therapy cancer and inflammatory diseases
Prof Anita Maguire Pharmaceutical Chemistry	Novel synthetic methodology including the use of α diazocarbonyl compounds and organosulfur compounds in synthesis Asymmetric synthesis including asymmetric catalysis and application of biotransformations in organic synthesis Continuous flow as a powerful technique to enhance process chemistry Synthesis of biologically active compounds Current projects are targeted towards compounds with anti-viral activity Crystal engineering – the pharmaceutical solid state
Dr Suzanne McCarthy Clinical Pharmacy	Healthcare Education Research Medication Safety Women’s and Children’s health Mental Health Pharmacoepidemiology/Drug Utilisation
Dr Rachel Moloney Pharmacology	Stress neurobiology: Understanding the role of the Hypothalamic Pituitary Adrenal Axis (HPA) and the impact of traumatic stress in fear memory, anxiety and depression Limbic neurocircuitry: Investigating the roles of discrete brain regions using cutting edge tools such as DREADDs/chemogenetics to directly manipulate neurocircuitry Brain-gut-microbiome axis: Studying the role of the gut microbiome in stress-related illnesses Pain: Investigating the impact of stress on pain sensitivity and nociception
Dr Kevin Murphy Clinical Pharmacy	Reducing deleterious effects of polypharmacy in older patients Interprofessional communication and patient communication Expanding pharmacy services in hospital environment
Prof Caitriona O'Driscoll Pharmaceutics	Physicochemical and physiological barriers to drug delivery Design and assessment of targeted drug delivery constructs Delivery of macromolecules including peptide/protein based drugs Non-viral methods for delivery of plasmid DNA and siRNA Oral drug absorption using lipid-based formulations Bioavailability and pharmacokinetics
Dr Patrick O'Dwyer Pharmaceutics	Biopharmaceutical profiling including biorelevant dissolution testing & Physiologically based pharmacokinetic (PBPK) modelling / Physiologically Based Biopharmaceutics Modelling (PBBM) Computational Pharmaceutics: applying machine learning and artificial intelligence to address pharmaceutical challenges, including formulation & process development Regulatory Science eg., applying innovative approaches to develop and assess complex generic products, such as inhalers Novel approaches to enhance oral drug delivery
Dr Joey O'Shea Pharmaceutics	Formulation development and characterisation for oral drug delivery of poorly soluble drugs. Lipid-based formulations for oral drug Computational biopharmaceutics and predictive modelling of bioavailability and pharmacokinetics. Development of nanoparticulate preparations for delivery of advanced
Dr Tim O'Sullivan Pharmaceutical Chemistry	Synthesis of bioactive compounds, including antiparasitic, antibacterial and antiviral compounds. Development of new methodologies for the synthesis of medicinally important compounds. Stereoselective synthesis of natural 1,2-dioxanes for the treatment of Chagas disease. Investigation of new chiral tethers for the control of intramolecular, aryl-aryl coupling and application to anti-HIV biaryls. Synthesis of Diffusible Signal Factor analogues to disrupt bacterial resistance in Cystic Fibrosis lung.
Dr Katie Ryan Pharmaceutics	Formulation approaches for poorly soluble drugs. Nanotechnology for targeted drug delivery. Biomaterials. Medical devices including hard and soft tissue implants. Regenerative medicine and tissue engineering.
Prof Laura Sahm Clinical Pharmacy	The role of the pharmacist in Public Health including; vaccinations and modification of solid oral dosage forms. Patient adherence to therapy and Health Literacy. Pharmacovigilance and the importance of medication reconciliation at the interface of primary and secondary care.
Dr Sonja Vucen Pharmaceutics	Transdermal drug delivery and enhancement of percutaneous absorption. Prediction and assessment of skin penetration and topical bioavailability and pharmacokinetics. Skin barrier function characterization. Design and assessment of microneedle drug delivery systems. Formulation and characterisation of peptide and protein therapeutics.
Prof Christian Waeber Pharmacology	Vascular biology: Investigating the role of S1P receptors, S1P synthesizing. enzyme and Store-Operated Calcium Entry in vascular disorders associated smooth muscle cell proliferation. Stroke and Neuroprotection: Studying the mechanisms by which S1P receptor stimulation in effective in rodent models of cerebral ischemia. Assessing the translational significance of these protective effects by using stroke models that are more relevant to humans (thromboembolic stroke, effect of comorbidities, age, etc.). Bone biology: Polymer-based delivery of S1P agents for bone repair.

School of Pharmacy Cógaisíocht

Staff Research Interests

School of Pharmacy

Cógaisíocht