2022 Publications

1. Spore exines increase vitamin D clinical bioavailability by mucoadhesion and bile triggered release

Diego-Taboada, A., Sathyapalan, T., Courts, F., Lorch, M., Almutairi, F., Burke, B. P., Harris, K., Kruusmägi, M., Walther, T., Booth, J., Boa, A. N., Archibald, S. J., Thompson, C., Atkin, S. L., & Mackenzie, G. (2022). Spore exines increase vitamin D clinical bioavailability by mucoadhesion and bile triggered release. Journal of controlled release : official journal of the Controlled Release Society350, 244–255. Advance online publication.

 

2. Recombinant pregnancy-specific glycoprotein-1-Fc reduces functional deficit in a mouse model of permanent brain ischaemia

Malone, K. Shearer J.A. , Williams , j.M. , Moore , A. , Moore , T. , Waeber, C. (2022) Recombinant pregnancy-specific glycoprotein-1-Fc reduces functional deficit in a mouse model of permanent brain ischaemia. Brain Behaviour & Immunity Health, 25.

 

 

3. Preclinical Evaluation of Fingolimod in Rodent Models of Stroke With Age or Atherosclerosis as Comorbidities

Andrea C. Diaz Diaz, Andrea C. Diaz Diaz, Malone, K., Malone, K., Shearer, J. A., Moore, A. C., & Waeber, C. (2022). Preclinical evaluation of fingolimod in rodent models of stroke with age or atherosclerosis as comorbidities. Frontiers in Pharmacology, 13

 

4. Ethanolamine: A Potential Promoiety with Additional Effects on the Brain

Gwanyanya, A., Godsmark, C. N., & Kelly-Laubscher, R. (2022). Ethanolamine: A Potential Promoiety with Additional Effects on the Brain. CNS & neurological disorders drug targets, 21(2), 108–117.

 

5. Trophic transfer of microplastics in a model freshwater microcosm; lack of
a consumer avoidance response

Mateos-Cárdenas, A., Moroney, Aran von der Geest, van Pelt, F. N. A. M., O'Halloran, J., & Jansen, M. A. K. (2022). Trophic transfer of microplastics in a model freshwater microcosm; lack of a consumer avoidance response. Food Webs, 31, e00228.

 

6. Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against α-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells

McCarthy, E., Barron, A., Morales-Prieto, N., Mazzocchi, M., McCarthy, C. M., Collins, L. M., Sullivan, A. M., & O'Keeffe, G. W. (2022). Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against α-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells. Molecular neurobiology, 59(5), 2745–2757. 

 

7. Computational Models on Pathological Redox Signalling Driven by Pregnancy: A Review

 Manna, S., Ruano, C., Hegenbarth, J. C., Vaiman, D., Gupta, S., McCarthy, F. P., Méhats, C., McCarthy, C., Apicella, C., & Scheel, J. (2022). Computational Models on Pathological Redox Signalling Driven by Pregnancy: A Review. Antioxidants (Basel, Switzerland), 11(3), 585.

 

8. Knowledge-driven feature engineering to detect multiple symptoms using ambulatory blood pressure monitoring data

Janjua, Z. H., Kerins, D., O’Flynn, B., & Tedesco, S. (2022). Knowledge-driven feature engineering to detect multiple symptoms using ambulatory blood pressure monitoring data. Computer Methods and Programs in Biomedicine, 217, 106638-106638.

 

9. Pulmonary arterial hypertension in hereditary hemorrhagic telangiectasia associated with ACVRL1 mutation: a case report. 

Walsh, L. J., Collins, C., Ibrahim, H., Kerins, D. M., Brady, A. P., & O Connor, T. M. (2022). Pulmonary arterial hypertension in hereditary hemorrhagic telangiectasia associated with ACVRL1 mutation: A case report. Journal of Medical Case Reports, 16(1), 99-99. 

 

10. The Rare Finding of Posteromedial Papillary Muscle Hypertrophy in Chronic Rheumatic Mitral Valve Disease

Lavery R, Kerins D. The Rare Finding of Posteromedial Papillary Muscle Hypertrophy in Chronic Rheumatic Mitral Valve Disease. Clin Med Rev Case Rep 8:344. 

 

11. Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies

 Alshaikh, R. A., Waeber, C., & Ryan, K. B. (2022). Polymer based sustained drug delivery to the ocular posterior segment: Barriers and future opportunities for the treatment of neovascular pathologies. Advanced Drug Delivery Reviews, 187, 114342-114342.

 

12. Bone regenerative potential of the selective sphingosine 1-phosphate receptor modulator siponimod: In vitro characterisation using osteoblast and endothelial cells

Sartawi, Z., Ryan, K. B., & Waeber, C. Bone regenerative potential of the selective sphingosine 1-phosphate receptor modulator siponimod: In vitro characterisation using osteoblast and endothelial cells. European journal of pharmacology, 882, 173262. 

 13. Treatment with Angiotensin-(1-7) Prevents Development of Oral Papilloma Induced in K-ras Transgenic Mice

 chere-Levy, C., Suberbordes, M., Ferri, D. M., Ayre, M., Gattelli, A., Kordon, E. C., Raimondi, A. R., & Walther, T. Treatment with Angiotensin-(1-7) Prevents Development of Oral Papilloma Induced in K-ras Transgenic Mice. International journal of molecular sciences, 23(7), 3642.

 

14. Flow cytometry and stroke: from current methodology to future applications

 Amu, S., & Malone, K. Flow cytometry and stroke: From current methodology to future applications. Neural Regeneration Research, 17(8), 1748-1750.

 

15. NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease

Anantha, J., Goulding, S. R., Tuboly, E., O'Mahony, A. G., Moloney, G. M., Lomansey, G., McCarthy, C. M., Collins, L. M., Sullivan, A. M., & O'Keeffe, G. W. (2022). NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease. Molecular neurobiology, 59(1), 61–76.

 

16. Acetyl-leucine slows disease progression in lysosomal storage disorders

 Kaya, E., Smith, D. A., Smith, C., Morris, L., Bremova-Ertl, T., Cortina-Borja, M., Fineran, P., Morten, K. J., Poulton, J., Boland, B., Spencer, J., Strupp, M., & Platt, F. M. (2020). Acetyl-leucine slows disease progression in lysosomal storage disorders. Brain communications, 3(1), fcaa148.

 

17. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Klionsky, …, Boland, B . Waeber, C. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy, 17(1), 1–382.

 

18. Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse

 Morais, L. H., Golubeva, A. V., Moloney, G. M., Moya-Pérez, A., Ventura-Silva, A. P., Arboleya, S., Bastiaanssen, T., O'Sullivan, O., Rea, K., Borre, Y., Scott, K. A., Patterson, E., Cherry, P., Stilling, R., Hoban, A. E., El Aidy, S., Sequeira, A. M., Beers, S., Moloney, R. D., Renes, I. B., … Cryan, J. F. (2020). Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse. Current biology : CB, 30(19), 3761–3774.e6.

 

19. Comparison of dental students' performances and perceptions in preclinical and clinical pharmacology in an Irish Dental School

Barry, O. P., & O'Sullivan, E. (2017). Comparison of dental students' performances and perceptions in preclinical and clinical pharmacology in an Irish Dental School. European journal of dental education : official journal of the Association for Dental Education in Europe, 21(4), e19–e28. 

 

20. The Patient-Held Active Record of Medication Status (PHARMS) study: a mixed-methods feasibility analysis

Walsh, E. K., Sahm, L. J., Bradley, C. P., Dalton, K., O'Sullivan, K., McCarthy, S., Connolly, E., Fitzgerald, C., Smithson, W. H., Kerins, D., Byrne, D., & Kearney, P. M. (2019). The Patient-Held Active Record of Medication Status (PHARMS) study: a mixed-methods feasibility analysis. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(682), e345–e355.

 

21. Fingolimod Does Not Reduce Infarction After Focal Cerebral Ischemia in Mice During Active or Inactive Circadian Phases

Mandeville, E. T., Li, W., Quinto-Alemany, D., Zhang, F., Esposito, E., Nakano, T., Mandeville, J. B., Lee, J., Park, J. H., Arai, K., Waeber, C., Lizasoain, I., Moro, M. Á., & Lo, E. H. (2022). Fingolimod Does Not Reduce Infarction After Focal Cerebral Ischemia in Mice During Active or Inactive Circadian Phases. Stroke. Advance online publication.

Department of Pharmacology and Therapeutics

Cógaseolaíocht agus Teiripic

Room 2.36B, 2nd floor floor, T12XF62

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