2021 Publications

 

1. Divergent Effects of Exendin-4 and Interleukin-6 on Rat Colonic Secretory and Contractile Activity are Associated with Changes in Regional Vagal Afferent Signaling.

 O'Brien, R., Buckley, M. M., & O'Malley, D. (2021). Divergent effects of exendin‐4 and interleukin‐6 on rat colonic secretory and contractile activity are associated with changes in regional vagal afferent signaling. Neurogastroenterology and Motility, 33(10),

 

2. Sphingosine 1-phosphate, a potential target in neovascular retinal disease

Alshaikh, R. A., Ryan, K. B., & Waeber, C. (2021). Sphingosine 1-phosphate, a potential target in neovascular retinal disease. Journal of Ophthalmology Published Online First: 07 May 2021. doi: 10.1136/bjophthalmol-2021-319115

 

3. Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE−/− mice in the presence and absence of immunomodulation with fingolimod

 Diaz Diaz, A. C., Malone, K., Shearer, J. A., Moore, A. C., & Waeber, C. (2021). Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE−/− mice in the presence and absence of immunomodulation with fingolimod. Data in Brief, 36, 107146-107146.

 

4. The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia

Malone, K., Diaz Diaz, A. C., Shearer, J. A., Moore, A. C., & Waeber, C. (2021). The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia. Journal of Neuroinflammation, 18(1), 37-37

 

5. Platelet hyperactivation and hyporesponsiveness at diagnosis in multiple myeloma persists during treatment initiation

 O'Sullivan, L. R., Meade-Murphy, G., Gilligan, O. M., Mykytiv, V., Cahill, M. R., & Young, P. W. (2021). Platelet hyperactivation and hyporesponsiveness at diagnosis in multiple myeloma persists during treatment initiation. Thrombosis Research, 203, 186-189

 

6. Adsorption, uptake and toxicity of micro- and nanoplastics: Effects on terrestrial plants and aquatic macrophytes

 Mateos-Cárdenas, A., van Pelt, F. N. A. M., O’Halloran, J., & Jansen, M. A. K. (2021). Adsorption, uptake and toxicity of micro- and nanoplastics: Effects on terrestrial plants and aquatic macrophytes. Environmental Pollution (1987), 284, 117183.

 

7Beyond Plastic Microbeads- Short-Term feeding of cellulose and polyester microfibers to the freshwater amphipod  Grammarus Dubeni 

Mateos-Cárdenas, A., O'Halloran, J., van Pelt, F. N. A. M., & Jansen, M. A. K. (2021). Beyond plastic microbeads – short-term feeding of cellulose and polyester microfibers to the freshwater amphipod gammarus duebeni. The Science of the Total Environment, 753, 141859-141859

 

8. Gestational Diabetes Mellitus and Maternal Immune Dysregulation: What We Know So Far' 

 McElwain, C. J., McCarthy, F. P., & McCarthy, C. M. (2021). Gestational diabetes mellitus and maternal immune dysregulation: What we know so far. International Journal of Molecular Sciences, 22(8), 4261.

 

9. Preeclampsia and neurodevelopmental outcomes: Potential pathogenic roles for inflammation and oxidative stress?'

 McElwain, C. J., McCarthy, F. P., & McCarthy, C. M. (2021). Gestational diabetes mellitus and maternal immune dysregulation: What we know so far. International Journal of Molecular Sciences, 22(8), 4261

 

10. A comparative study of two immunoassays of maternal placental growth factor'

Hayes-Ryan, D., O'Donoghue, K., McCarthy, C., Totorika, A., & Meaney, S. (2021). A comparative study of two immunoassays of maternal placental growth factor. Scandinavian Journal of Clinical and Laboratory Investigation, 81(3), 167-172.

 

11. Localization and expression of the Mas-related G-protein coupled receptor member D (MrgD) in the mouse brain

 Hami, J., von Bohlen und Halbach, Viola, Tetzner, A., Walther, T., & von Bohlen und Halbach, Oliver. (2021). Localization and expression of the mas-related G-protein coupled receptor member D (MrgD) in the mouse brain. Heliyon, 7(11), e08440-e08440

 

12. Combining VEGF receptor inhibitors and angiotensin-(1-7) to target renal cell carcinoma

Walther, T., Khanna, P., & Bhatt, R. S. (2021). Combining VEGF receptor inhibitors and angiotensin-(1-7) to target renal cell carcinoma. Molecular & cellular oncology, 8(4), 1918529. 

 

13. Angiotensin-(1-7)-A Potential Remedy for AKI: Insights Derived from the COVID-19 Pandemic

Heyman, S. N., Walther, T., & Abassi, Z. (2021). Angiotensin-(1-7)-A Potential Remedy for AKI: Insights Derived from the COVID-19 Pandemic. Journal of clinical medicine, 10(6), 1200.

 

14. Measurement of multiple cytokines for discrimination and risk stratification in patients with Chagas' disease and idiopathic dilated cardiomyopathy

Wang, Y., Wessel, N., Kohse, F., Khan, A., Schultheiss, H. P., Moreira, M., & Walther, T. (2021). Measurement of multiple cytokines for discrimination and risk stratification in patients with Chagas' disease and idiopathic dilated cardiomyopathy. PLoS neglected tropical diseases, 15(3), e0008906. 

 

15. ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma

 Khanna, P., Soh, H. J., Chen, C. H., Saxena, R., Amin, S., Naughton, M., Joslin, P. N., Moore, A., Bakouny, Z., O'Callaghan, C., Catalano, P., Signoretti, S., McKay, R., Choueiri, T. K., Bhasin, M., Walther, T., & Bhatt, R. S. (2021). ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma. Science translational medicine, 13(577), eabc0170.

 

16. Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation

 Erfinanda, L., Ravindran, K., Kohse, F., Gallo, K., Preissner, R., Walther, T., & Kuebler, W. M. (2021). Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation. The European respiratory journal, 57(1), 2000921.

 

17. Cardioprotective effect of fingolimod against calcium paradox-induced myocardial injury in the isolated rat heart.

Alatrag, Fatma, Matthew Amoni, Roisin Kelly-Laubscher, and Asfree Gwanyanya. "Cardioprotective Effect of Fingolimod Against Calcium paradox–induced Myocardial Injury in the Isolated Rat Heart." Canadian Journal of Physiology and Pharmacology 100, no. 2 (2021): 134-141.

 

18. Acute Treatment With Fingolimod Does Not Confer Long-Term Benefit in a Mouse Model of Intracerebral Haemorrhage

 Diaz Diaz, A. C., Shearer, J. A., Malone, K., & Waeber, C. (2021). Acute Treatment With Fingolimod Does Not Confer Long-Term Benefit in a Mouse Model of Intracerebral Haemorrhage. Frontiers in pharmacology, 11, 613103.

 

19. A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile

 Twomey, L., Navasiolava, N., Robin, A., Bareille, M. P., Gauquelin-Koch, G., Beck, A., Larcher, F., Meade-Murphy, G., Sheridan, S., Maguire, P. B., Harrison, M., Degryse, B., Moyna, N. M., Gharib, C., Custaud, M. A., & Murphy, R. P. (2021). A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile. Scientific reports, 11(1), 21906.

 

20. Guideline-led prescribing to ambulatory heart failure patients in a cardiology outpatient service

El Hadidi, S., Vaughan, C., Kerins, D., Byrne, S., Darweesh, E., & Bermingham, M. (2021). Guideline-led prescribing to ambulatory heart failure patients in a cardiology outpatient service. International journal of clinical pharmacy, 43(4), 1082–1089.

 

21.Platelet Hyperactivation in Multiple Myeloma Is Also Evident in Patients with Premalignant Monoclonal Gammopathy of Undetermined Significance.

O’Sullivan, L. R., MeadeMurphy, G., Gilligan, O. M., Mykytiv, V., Young, P. W., & Cahill, M. R. (2021). Platelet hyperactivation in multiple myeloma is also evident in patients with premalignant monoclonal gammopathy of undetermined significance. British Journal of Haematology, 192(2), 322-332.  

Department of Pharmacology and Therapeutics

Cógaseolaíocht agus Teiripic

Room 2.36B, 2nd Floor, Western Gateway Building, University College Cork, Cork

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