2018 Publications

 

1. The role and mechanisms of sphingosine kinase 2 in cerebral preconditioning-induced autophagy activation

 Sheng, R., Song, D., Zhang, T., Chen, J., Xia, Y., Qin, Z., & Waeber, C. (2018). The role and mechanisms of sphingosine kinase 2 in cerebral preconditioning-induced autophagy activation. Proceedings for Annual Meeting of the Japanese Pharmacological Society, WCP2018, PO4-1-27.

 

2. Platelets - From Formation to Function (Book chapter).

Twomey L, Wallace RG, Cummins PM, Degryse B, Sheridan S, Harrison M, Moyna N, Meade-Murphy G, Navasiolava N, Custaud M-A, Murphy RP.   In Homeostasis - An Integrated Vision. Publisher: InTechOpen; Pub. Date: 2018.

 

3. Platelets - Functional Biomarkers of Epigenetic Drift (Book chapter).

Twomey L, Wallace RG, Mangone M, Degryse B, Sheridan S, Harrison M, Moyna M, Meade-Murphy G, Nastassia Navasiolava N, Custaud M-A, Murphy RP. In Homeostasis - An Integrated Vision. Publisher: InTechOpen; Pub. Date: 2018.

 

4. Platelet Analysis (Patent).

Lourdes Basabe-Desmonts, Sofia Ramstrom, Antonio Ricco, Kenny Dermot, Gerardene Meade, Sarah O'neill, Asif Riaz, Luke Lee. Patent office: US; Publication date: 2018/4/10; Patent no: 9939430; Application no. 13123411.

 

5. Neprilysin degrades murine Amyloid-β (Aβ) more efficiently than human Aβ: Further implication for species-specific amyloid accumulation. Neuroscience Letters

Becker, M., Moore, A., Naughton, M., Boland, B., Siems, W., & Walther, T. (2018). Neprilysin degrades murine amyloid-β (Aβ) more efficiently than human Aβ: Further implication for species-specific amyloid accumulation. Neuroscience Letters, 686, 74-79.

 

6. Consensus document on the management of hyperkalaemia in patients with cardiovascular disease treated with RAAS-inhibitors - Coordinated by the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology

Rosano, G. M. C., Tamargo, J., Kjeldsen, K. P., Lainscak, M., Agewall, S., Anker, S. D., Ceconi, C., Coats, A. J. S., Drexel, H., Filippatos, G., Kaski, J. C., Lund, L., Niessner, A., Ponikowski, P., Savarese, G., Schmidt, T. A., Seferovic, P., Wassmann, S., Walther, T., & Lewis, B. S. (2018). Expert consensus document on the management of hyperkalaemia in patients with cardiovascular disease treated with renin angiotensin aldosterone system inhibitors: Coordinated by the working group on cardiovascular pharmacotherapy of the european society of cardiology. European Heart Journal. Cardiovascular Pharmacotherapy, 4(3), 180-188.

 

7. Decarboxylation of Ang-(1-7) to Ala1-Ang-(1-7) leads to significant changes in pharmacodynamics

Tetzner, A., Naughton, M., Gebolys, K., Eichhorst, J., Sala, E., Villacañas, Ó., & Walther, T. (2018). Decarboxylation of ang-(1–7) to Ala1-ang-(1–7) leads to significant changes in pharmacodynamics. European Journal of Pharmacology, 833, 116-123.

 

8. Non-insulin Antidiabetic Pharmacotherapy in Patients with Established Cardiovascular Disease: a Position Paper of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy

Niessner, A., Tamargo, J., Koller, L., Saely, C. H., Schmidt, T. A., Savarese, G., Wassmann, S., Rosano, G., Ceconi, C., Torp-Pedersen, C., Kaski, J. C., Kjeldsen, K. P., Agewall, S., Walther, T., Drexel, H., & Lewis, B. S. (2018). Non-insulin antidiabetic pharmacotherapy in patients with established cardiovascular disease: A position paper of the european society of cardiology working group on cardiovascular pharmacotherapy. European Heart Journal, 39(24), 2274-2281.

 

9. Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing. Nat Rev Drug Discov

Boland, B., Yu, W. H., Corti, O., Mollereau, B., Henriques, A., Bezard, E., Pastores, G. M., Rubinsztein, D. C., Nixon, R. A., Duchen, M. R., Mallucci, G. R., Kroemer, G., Levine, B., Eskelinen, E., Mochel, F., Spedding, M., Louis, C., Martin, O. R., & Millan, M. J. (2018). Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery, 17(9), 660-688.

 

10. No evidence in support of a prodromal respiratory control signature in the TgF344-AD rat model of Alzheimer's disease.Respir Physiol Neurobiol

Lucking, E. F., Murphy, K. H., Burns, D. P., Jaisimha, A. V., Barry-Murphy, K. J., Dhaliwal, P., Boland, B., Rae, M. G., & O’Halloran, K. D. (2018). No evidence in support of a prodromal respiratory control signature in the TgF344-AD rat model of Alzheimer’s disease. Respiratory Physiology & Neurobiology, 265, 55-67.

 

11. Wood ash residue causes a mixture of growth promotion and toxicity in Lemna Minor

Jagodzinski, L. S., O'Donoghue, M. T., Heffernan, L. B., van Pelt, Frank N. A. M, O'Halloran, J., & Jansen, M. A. K. (2018). Wood ash residue causes a mixture of growth promotion and toxicity in lemna minor

 

12. Development of an ex Vivo Method for Multi-unit Recording of Microbiota-Colonic-Neural Signaling in Real Time

Buckley, M. M., & O'Malley, D. (2018). Development of an ex vivo method for multi-unit recording of microbiota-colonic-neural signaling in real time. Frontiers in Neuroscience, 12, 112-112.

 

13. Exploring the role of mitochondrial dysfunction in the pathophysiology of pre-eclampsia. Pregnancy Hypertension

Williamson, R. D., McCarthy, F. P., Khashan, A. S., Totorika, A., Kenny, L. C., & McCarthy, C. (2018). Exploring the role of mitochondrial dysfunction in the pathophysiology of pre-eclampsia. Pregnancy Hypertension, 13, 248-253.

 

14. Biomarkers of Glomerular Dysfunction in Pre-eclampsia - A Systematic Review. Pregnancy Hypertension

Kerley, R. N., & McCarthy, C. (2018). Biomarkers of glomerular dysfunction in pre-eclampsia – A systematic review. Pregnancy Hypertension, 14, 265-272.

 

15. The potential therapeutic effects of L-ergothioneine in Pre-eclampsia. Free Radical Biology and Medicine

Kerley, R. N., McCarthy, C., Kell, D. B., & Kenny, L. C. (2018). The potential therapeutic effects of ergothioneine in pre-eclampsia. Free Radical Biology & Medicine, 117, 145-157 

 

16. Platelets: From Formation to Function

Twomey L, Wallace RG, Cummins PM, Bernard Degryse B, Sheridan S, Harrison M, Moyna N, Meade-Murphy G, Navasiolava N, Custaud MA, Murphy RP. Homeostasis: An Integrated Vision. Publisher: IntechOpen; Editors, Fernanda Lasakosvitsch F and Garnes SDA. Book chapter 5, 71-92

 

17. Platelets: Functional Biomarkers of Epigenetic Drift

Twomey L, Wallace RG, Mangone M, Degryse B, Sheridan S, Harrison M, Moyna N, Meade-Murphy G, Navasiolava N, Custaud MA, Murphy RP. Homeostasis: An Integrated Vision. Publisher: IntechOpen; Editors, Lasakosvitsch F, Garnes SDA. Book Chapter 6, 93-120,

 

18. Shear-Mediated Platelet Adhesion Analysis in Less Than 100 μ L of Blood: Toward a POC Platelet Diagnostic

Kent, N. J., O'Brien, S., Basabe-Desmonts, L., Meade, G. R., MacCraith, B. D., Corcoran, B. G., Kenny, D., & Ricco, A. J. (2011). Shear-mediated platelet adhesion analysis in less than 100 μ L of blood: Toward a POC platelet diagnostic. IEEE Transactions on Biomedical Engineering, 58(3), 826-830.

Department of Pharmacology and Therapeutics

Cógaseolaíocht agus Teiripic

Room 2.36B, 2nd Floor, Western Gateway Building, University College Cork, Cork

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