2009 Press Releases

UCC scientists publish in prestigious journal
29.06.2009

A team of scientists led by Dr Max Dow and Dr Robert Ryan at the BIOMERIT Research Centre, Department of Microbiology, UCC has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients.
The international research team which included scientists from Ireland, Austria, and the United Kingdom as well as the US was investigating the versatility and adaptability of a group of bacteria known as Stenotrophomonas. These bacteria have great metabolic versatility, allowing them to thrive in very diverse environments and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

The scientists were particularly interested in comparing two strains of S. maltophilia whose genomes were recently decoded to see why these strains — one isolated as an opportunistic pathogen from a clinical setting (strain K279a), and the other from the roots of poplar trees (strain R551-3) — were so well-suited to their very different environments. Such comparisons are made possible by the high throughput and cost-effective DNA sequencing capacity developed by DOE’s Joint Genome Institute, as well as the Sanger Institute, to help elucidate the role of microorganisms in health, energy, and environmental processes.

Co-authors on this study include: Robert P. Ryan and J. Maxwell Dow of University College Cork; Sebastien Monchy and Safiyh Taghavi of Brookhaven Lab; Massimiliano Cardinale and Gabriele Berg of Graz University of Technology, Austria; Lisa Crossman of The Wellcome Trust Sanger Institute, UK; and Matthew B. Avison of the University of Bristol, UK.

Brookhaven Lab’s contribution to this study was supported by grants from DOE’s Office of Science, Laboratory Directed Research and Development funds, and by Royalty Funds at Brookhaven Lab under contract with DOE. Sequencing of R551-3 was performed at the DOE Joint Genome Institute. Other aspects of the research were funded by the German Research Foundation, the Austrian Science Foundation, INTAS, the Wellcome Trust, the British Society for Antimicrobial Chemotherapy, and Science Foundation Ireland.

Visit: http://www.nature.com/nrmicro/journal/v7/n7/full/nrmicro2163.html
Reference: Robert P. Ryan, Sebastien Monchy,  Massimiliano Cardinale,  Safiyh Taghavi,  Lisa Crossman, Matthew B. Avison, Gabriele Berg,  Daniel van der Lelie  &  J. Maxwell Dow (2009) The versatility and adaptation of bacteria from the genus Stenotrophomonas. Nature Reviews Microbiology 7, 514-525 | doi:10.1038/nrmicro2163.

Picture:  Journal cover for July

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