Beth Brint is a Senior Lecturer in the Pathology Department, UCC, Funded Investigator in APC Microbiome Ireland, Faculty member of CancerResearch@UCC, currently a Health Research Board funded investigator and previously a Science Foundation Ireland funded Investigator. Beth completed her BSc (Hons) in Biochemistry at the University of Sussex, England. She subsequently undertook a PhD in the Biochemistry Department, Trinity College Dublin investigating molecular mechanism regulating the inflammatory/immune response. She developed her expertise in regulation of immune signalling by performing postdoctoral studies jointly between Trinity College Dublin and Xoma Ltd, a San Francisco based pharmaceutical company and subsequently in APC Microbiome Ireland. In 2008 she competitively obtained a tenured position at UCC as a Lecturer in Pathology.
Research in Beth’s laboratory focuses on innate immune responses, with a particular emphasis on the regulation and function of innate immunity in the gastrointestinal tract in both health and disease. Of particular relevance to her group are inflammatory receptor families (Toll-Like Receptors; IL-1 family; Death receptors) that contribute to intestinal diseases such as inflammatory bowel diseases and colorectal cancer. This work fits with her roles within both APC Microbiome Ireland and Cancer Research@UCC. She has a number of collaborations with academic and clinical partners, has published over 30 peer-reviewed articles, most as senior author, in high impact journals with her work cited >6400 times. She has secured funding for her research from multiple funding sources including charities (Breakthrough Cancer Research) and national funding bodies (Health Research Board/Science Foundation Ireland/Irish Research Council).
Research theme: Theme 4 Host-Microbe dialogue
SDGs: SDG3: Good Health and wellbeing
Research key words: Innate immunity, inflammation, cancer, cancer immunology