Abstract

Mid-trimester pregnancy loss, defined as a pregnancy loss occurring between 14 weeks + 0 days and 21 weeks + 6 days of pregnancy, causes significant physical and emotional distress to women. Risk factors include older maternal age, previous mid-trimester loss, Black ethnicity, smoking, excessive alcohol use, obesity, anatomical factors such as a short cervix, congenital uterine anomalies, and other medical risk factors.

Early medical assessment and accurate diagnosis are key to managing threatened and confirmed mid-trimester pregnancy loss. A multidisciplinary approach involving obstetricians, gynaecologists, maternal-fetal medicine specialists, nurses, midwives, psychologists, and social workers is important for providing comprehensive care. The guideline advocates for personalised management plans tailored to individual women's preferences, medical history, and stage of the pregnancy.  

Offering compassionate and culturally sensitive psychosocial support to women and their families at the time of / after pregnancy loss is important. This includes providing access to bereavement care, counselling services, support groups, and resources for coping with grief and loss. Continued monitoring and follow-up care are essential. It is important that, where possible, women receive care from the same healthcare professionals to help the coordination and provision of comprehensive care. By following the recommendations in this clinical guideline, healthcare providers can try to optimise outcomes and support individuals and their families.