Publications

Infertility and subsequent recurrent miscarriage: Current state of the literature and future considerations for practice and research

Narrative review demonstrating women/couples with RM and infertility appear indirectly in studies evaluating investigations and treatments. High-quality studies are lacking. Furthermore, they are largely excluded from international clinical guidance and qualitative research.

Authors
Laura Linehan, Marita Hennessy, Keelin O'Donoghue
Year
2021
Journal Name
HRB Open Research
Category
Journal Article
Keywords
Infertility / IVF / Medically Assisted Reproduction, Recurrent miscarriage
Full Citation
Linehan L, Hennessy M, O'Donoghue K. Infertility and subsequent recurrent miscarriage: Current state of the literature and future considerations for practice and research [version 1; peer review: 1 approved with reservations]. HRB Open Research. 2021;4:100. https://doi.org/10.12688/hrbopenres.13397.1.
Link to Publication
https://doi.org/10.12688/hrbopenres.13397.1

Abstract

Globally, infertility rates are increasing, and more couples need fertility treatments to achieve a pregnancy. Recurrent miscarriage is defined differently around the world, referring to two or three consecutive pregnancy losses up to 24 weeks of gestation. In this study, we examined the investigations and treatments for men and women who have infertility and go on to experience recurrent miscarriage. We also examined international guidelines discussing RM and infertility, to see if there were any particular recommendations regarding support or treatments. We found that, while women and men experiencing RM after infertility do appear in studies, these studies are often small and few high-quality studies such as randomized control trials are available. Just one qualitative study captured the experiences of women who have had RM after infertility. The international guidelines on RM do not consider women and men with infertility. These findings demonstrate a distinct gap in the literature, informing us that more research is needed in this area and that women and men with infertility experiencing RM need greater consideration and support.

Pregnancy Loss Research Group

Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, University College Cork, Fifth Floor, Cork University Maternity Hospital, Wilton, Cork, T12 YE02, Ireland,

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