Placental growth factor: A review of literature and future applications

Placental growth factor (PlGF) is highly expressed during pregnancy and correlates well with placental function. Quantification of PlGF and its specific receptors may have utility as a diagnostic marker of placental disease or as an indicator of adverse pregnancy outcomes.


Deirdre Hayes Ryan, Keelin O'Donoghue

Journal Name
Pregnancy Hypertension
Journal Article
Full Citation

Hayes Ryan D, McCarthy FP, O'Donoghue K, Kenny LC. Placental growth factor: A review of literature and future applications. Pregnancy Hypertension. 2018;14:260-264.

Link to Publication


Placental growth factor (PlGF) is a protein that is made by the placenta during pregnancy. The levels of PlGF protein in the mother correspond well with the growth and health of the placenta. Low levels of PlGF may be used to identify a placenta that is not working well and pregnancies that are more at risk of poor outcomes.

Pregnancy Loss Research Group

Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, University College Cork, Fifth Floor, Cork University Maternity Hospital, Wilton, Cork, T12 YE02, Ireland,