Publications

The role of perinatal pathology in the investigation of stillbirth

An unexplained stillbirth may simply be an uninvestigated one. With specialist pathology services, and an increase in postmortem investigations, there has been a significant decrease in the number of stillbirths whose cause of death is unexplained.

Authors
Danielle Barry, Anna Maria Verling, Brendan Fitzgerald, Keelin O'Donoghue
Year
2016
Journal Name
British Journal of Obstetrics and Gynecology (BJOG)
Category
Journal Article
Keywords
Perinatal pathology, Stillbirth
Full Citation
Barry D, Verling AM, Fitzgerald B, O’Donoghue K. The role of perinatal pathology in the investigation of stillbirth. British Journal of Obstetrics and Gynecology. 2016;123(S1):41. https://doi.org/10.1111/1471-0528.13989.
Link to Publication
https://doi.org/10.1111/1471-0528.13989

Abstract

Stillbirth is defined as infants born after 24 weeks of gestation and weighing >500 g, showing no signs of life. An unexplained stillbirth may simply be an uninvestigated one, and finding a cause is hugely important for parents and clinicians. Perinatal pathology provides valuable information in determining the cause of stillbirth, through specialised examinations on the infant and placenta. We aimed to demonstrate the impact of perinatal pathology in determining cause of death in stillbirths in a university teaching hospital delivering over 8000 infants annually. A perinatal pathologist was appointed in 2012. All stillbirths from 2008 to 2014 were identified (n=259). From 2008 to 2014 the uptake rate of perinatal postmortems increased by 27% with a corresponding decrease of 39% in unexplained stillbirths. In 2008, 2010 and 2012 the rates of postmortems performed were 56%, 51% and 53%, respectively with an increase to 77% in 2014. Overall, 26% of stillbirths were unexplained; although 36% of these had no postmortem examination. By 2014 only 5% of stillbirths were categorised as unexplained. With specialist pathology services available since 2012 and an increase in postmortem investigations, there has been a significant decrease in the number of stillbirths whose cause of death is unexplained.

Pregnancy Loss Research Group

Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, University College Cork, Fifth Floor, Cork University Maternity Hospital, Wilton, Cork, T12 YE02, Ireland,

Top