Experimental Modalities


  • Angiography-vascular, coronaries, ventricle
  • PCI, stent – invasive/non invasive assessment
  • Hemodynamics
  • Press volume loops, FFR, CFR
  • 2-D , 3D angiography
  • Regional wall, myocardial infarct size assessment Non invasive valve assessment
  • Plaque area and volume assessment
  • Coronary flow and ischemia analysis
  • Biochemical and molecular tagging and tracking of molecules, tracers, cells, devices
  • Potential for detection of unstable plaque
  • Intravascular Ultrasound


Basic Science Investigative Resources



  • Cell and Tissue Culture facilities (3 laminar flow hoods, 6 incubators)
  • Full Protein, DNA and RNA analysis
  • Western blotting, ELISA and HPLC
  • RT-PCR including quantitative,
  • Northern and Southern Blotting,
  • RNAi of target genes
  • Lentiviral vector design and production



  • Nikon TE-2000E Confocal Laser Microscopy
  • Laser Intravital Microscopy
  • Real-time cell analyses under flow
  • Resin-embedding for Stented Vessel Sectioning


With collaborators

  • Olympus Two-photon microscopy
  • Olympus Spectral Scanning Confocal Microscopy


Flow Cytometry

  • BD FACSCalibur 4-colour flow cytometer
  • BD FACS Aria II 7-colour cell sorting


Small Animal Surgery

  • Generation of bone marrow chimerics and transgenics
  • Myocardial infarction; total occlusion or with reperfusion
  • Angioplasty-mediated vascular injury




University College Cork

Coláiste na hOllscoile Corcaigh

College Road, Cork T12 K8AF