The MILESTONE Study

The MILESTONE study

Multiple pregnancy: An investigation of the risk factors and outcomes in the Republic of Ireland

What is the MILESTONE Study?

The MILESTONE STUDY is a doctoral research study for Caroline O’Connor and is funded by the Irish research council. 

The overall aim of this study is to identify the risk factors and outcomes for those who experience twin pregnancies in the Republic of Ireland, to evaluate clinical practice guidelines, and to identify the specific service needs of this group, to inform future developments and help improve the quality of care within the maternity services. 

A twin pregnancy is considered a high-risk pregnancy and presents unique challenges for both families and health care providers. There is a need for consistent clinical care that follows the best evidence-based practice. In the absence of biomarkers and effective algorithms to predict adverse outcomes in multiple pregnancies we need to ensure the guidelines for the antenatal management of twin pregnancies are of high quality and gaps are identified as a focus for future guideline development and updates.

The MILESTONE Study aims to:

  • Identify the maternal and care-related risk factors associated with perinatal mortality and explore perinatal mortality within the twin population in the ROI.
  • Identify neonatal outcomes of twin pregnancies in the ROI.
  • Examine the current maternity care provided for the antenatal management of dichorionic diamniotic (DCDA) twin pregnancies, through the identification and appraisal of international clinical practice guidelines
  • Audit maternity hospitals within the ROI on the provision of the antenatal care to DCDA twin pregnancies and establish if the care provided is in line with national and international recommendations.
  • Identify the specific service needs of stakeholders, so as to inform future developments and help improve the quality of care within the maternity services. 

Who is involved?

This PhD study is being carried out by Caroline O’Connor (INFANT, UCC). The study is led by Prof. Keelin O’Donoghue (CUMH, UCC) and Dr. Sara Leitao (NPEC) with the collaboration of Dr Irene O’ Farrell (NPEC), Dr Anne Twomey (NMH) and Dr Emily O’Connor (CUMH, UCC).

Funding:

This project is funded by the Government of Ireland postgraduate funding from the Irish Research Council in 2020. 

Department of Obstetrics and Gynaecology

An Roinn Obstatraice agus Gínéiceolaíochta

Cork University Maternity Hospital, 5th Floor, Wilton, Cork, Ireland

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