The impact of fingolimod on Treg function in brain ischaemia
Fingolimod has generally shown neuroprotective effects in stroke models. Here, we tested the hypothesis that fingolimod modulates T-cell cytokine production towards a regulatory phenotype. Second, we investigated how fingolimod altered the Treg suppressive function and the sensitivity of effector T cells to regulation.
- Authors
Kyle Malone, Jennifer A. Shearer, Christian Waeber, Anne C. Moore.
- Year
- 2023
- Journal Name
- European Journal of Immunology
- Category
- Journal Article
- Full Citation
Malone, K., Shearer, J.A., Waeber, C. and Moore, A.C. (2023), The impact of fingolimod on Treg function in brain ischaemia. Eur. J. Immunol., 53: 2350370.
- Link to Publication
- https://onlinelibrary.wiley.com/doi/10.1002/eji.202350370