Adverse drug reactions and associated patient characteristics in older community-dwelling adults: a 6-year prospective cohort study
To date, research on adverse drug reactions (ADRs) has focused on secondary care, and there is a paucity of studies that have prospectively examined ADRs affecting older adults in general practice. This prospective cohort study of ADRs in general practice shows that over one-quarter of older adults experienced an ADR over a 6-year period. Polypharmacy is independently associated with ADR risk in general practice and older adults on ≥10 drug classes should be prioritised for regular medication review.
- Authors
Ann S Doherty 1, Fiona Boland 2, Frank Moriarty 3, Tom Fahey 1, Emma Wallace 4.
- Health Research Board (HRB) Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland (RCSI) University of Medicine and Health Sciences, Dublin.
- HRB Centre for Primary Care Research, Department of General Practice, RCSI University of Medicine and Health Sciences, Dublin 2, Ireland; Data Science Centre, RCSI University of Medicine and Health Sciences, Dublin.
- School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin.
- HRB Centre for Primary Care Research, Department of General Practice, RCSI University of Medicine and Health Sciences, Dublin; Department of General Practice, University College Cork, Cork.
- Year
- 2023
- Journal Name
- The British Journal of General Practice
- Category
- Journal Article
- Full Citation
Ann S Doherty, Fiona Boland, Frank Moriarty, Tom Fahey, Emma Wallace. Adverse drug reactions and associated patient characteristics in older community-dwelling adults: a 6-year prospective cohort study. Br J Gen Pract. 2023 Feb 23;73(728):e211-e219.
- Link to Publication
- https://pubmed.ncbi.nlm.nih.gov/36823047/