Overview

The Preclinical Platform is fundamental to APC research in providing an on-campus resource of animal models of infection, inflammation, cancer, obesity and allergy that the APC has built up over the last decade. Where interventions or microbial effects cannot be validated solely using in vitro systems, the Preclinical Platform provides expertise on validation of small molecules, probiotics and dietary interventions in a wide range of models, covering the areas of immunology, microbiology, cancer, metabolism and psychology/behaviour. The unit has also access to imaging technologies such as In Vivo Imaging System (IVIS), rodent endoscopy and body composition analyser. The value of these in vivo systems is further enhanced by the Germ-Free Platform Technology.

Responsible Investigators

• Silvia Melgar
• Pat Fitzgerald
• Pat Casey