Dr Sinéad Corr is an Associate Professor at the Dept. of Microbiology, Trinity College Dublin, where she leads the Microbiome & Mucosal Immunity Research Group, and a Funded Investigator at APC Microbiome Ireland. Sinéad qualified with a BSc Microbiology in 2002 and in 2006 with a PhD in Molecular Microbiology from University College Cork (UCC). This was followed by postdoctorate work as part of a collaboration between GlaxoSmithKline and the Alimentary Pharmabiotic Centre UCC (now APC Microbiome Ireland) (2006-2008) and subsequently with Prof. Luke O’Neill’s Inflammation Research Group, at the School of Biochemistry and Immunology, Trinity College Dublin (TCD) (2008-2015). In 2011, Sinéad was awarded a Science Foundation Ireland Starting Investigator Research Grant and in 2015, obtained an academic position in the Dept. of Microbiology, TCD, where she established the Microbiome & Mucosal Immunity research lab. Sinéad subsequently received a Crohn’s and Colitis Foundation of America, Litwin IBD Pioneer award and an SFI Frontiers for the Future award.
Research Interests: Dr Corr’s research focusses primarily on the host-microbe interface within the GI tract. Using molecular based approaches combined with animal models and clinical samples, Dr Corr’s research team target Microbiome, Metabolome, cytokine and microRNA networks to understand how healthy immune responses are maintained at the intestinal mucosal barrier and what processes over-ride this during disease, and in response to dietary and environmental components. A key focus of this research is on IBD. Dr Corr’s research has a strong translational focus, maintained by active collaboration with clinician colleagues and industrial biopharma partners, with the aim of identifying therapeutic strategies or novel dietary interventions and bioactives to manipulate intestinal immunity and enhance the beneficial aspects of the gut microbiome, with the ultimate goal of boosting gut health and reducing the severity of intestinal infectious and inflammatory diseases.
Theme: Host-Microbe Dialogue
SDG: 3 Good Health and Wellbeing
Key Research words: Microbiome; Metabolome; Mucosal Immunity; Inflammation; Infection & Immunity; IBD; Epithelial Barrier; Postbiotics; Dietary Intervention