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John Cryan


John F. Cryan MRIA is Vice President for Research & Innovation (VPRI), a Professor in the Department of Anatomy & Neuroscience, and a Principal Investigator at APC Microbiome Ireland. He received a B.Sc. (Hons) in Biochemistry and PhD in Pharmacology from the National University of Ireland, Galway, Ireland and was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia, which was followed by postdoctoral fellowships at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California. He spent four years as a Group Leader in the pharmaceutical industry at the Novartis Institutes for BioMedical Research in Basel Switzerland prior to joining UCC in 2005. Prof. Cryan's current research is focused on understanding the interaction between brain, gut & microbiome and how it applies to stress, psychiatric and immune-related disorders at key time-windows across the lifespan. Prof. Cryan has published over 600 peer-reviewed articles and book chapters and has a H-index of 140 (Google Scholar; May 2022). He is a Senior Editor of Neuropharmacology and of Neurobiology of Stress. He is on the editorial board of a further 15 journals. He has co-edited four books and is co-author of the bestselling “The Psychobiotic Revolution: Mood, Food, and the New Science of the Gut-Brain Connection” (National Geographic Press, 2017). He has received numerous awards including UCC Researcher of the Year in 2012, the University of Utrecht Award for Excellence in Pharmaceutical Research in 2013, UCC Research Communicator of the Year 2017, and being named on the Thomson Reuters Highly Cited Researcher list in 2014 and Clarivate Analytics Highly Cited Researcher list each year from 2017. He was elected a Member of the Royal Irish Academy in 2017 and has served on UCC’s Governing Body for 6 years. He also received a Research Mentor Award from the American Gastroenterology Association and the Tom Connor Distinguished Scientist Award from Neuroscience Ireland in 2017 and was awarded an honorary degree from the University of Antwerp, Belgium in 2018. He was a TEDMED speaker in Washington in 2014 and is Past-President of the European Behavioural Pharmacology Society.‍

Research Interests

Theme: Microbiota-Gut-Brain Axis

SDGs: 3 Good health and wellbeing; 4 Quality Education; 5 Gender Equality; 8 Decent work and economic growth; 9 Industry, innovative and infrastructure; 10 Reduced inequalities; 12 Responsible consumption and production; 16 Peace, justice and strong institutions

Interests/Key words:

Neurobiology of stress-related disorders including depression, anxiety, drug addiction, cognitive dysfunction and irritable bowel syndrome (IBS)

Microbiome, brain & behaviour across the lifespan

Immune-Brain interactions

siRNA-induced gene silencing in the brain in vivo.


Professional Activity


APC Microbiome Ireland, Biosciences Building, University College Cork, Ireland,