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Methodology Monday May Roundup

For Methodology Monday in May, we open with an editorial that discusses the current changes taking place in clinical research globally as a result of the current American climate. Then the focus shifts to the importance of thinking of health equity and diversity for the development of guidelines and patient and public involvement. To conclude, the impact of exclusion criteria in stroke patients is discussed.
To kick off the first #MethodologyMonday of May, we bring you a very poignant article by the Editors in Chief of the Journal of Clinical Epidemiology, Drs David Tovey and Andrea Tricco. They address the “elephant in the room”, the upheaval of the global evidence research eco-systems pursued by the US administration.
Ref. Tovey, D & Tricco, A (2025). Editorial, April 2025, Journal of Clinical Epidemiology.
This commentary by Dweidar and colleagues speaks about the lack of health equity as a principle in the development of guidelines. Applying a use case focusing on leprosy management, they look at the consequences of guideline recommendations on the population most affected. This #MethodologyMonday article then focuses on some common challenges and potential solutions for integrating health equity into real-world experiences.
We try to think about our trial participants and ensure they come from diverse communities. But this week for #MethodologyMonday, let’s increase our vision: what about patient and public involvement contributors? Do we consider the diverse representation here? This is a study led by Shoba Dawson, which looks at the involvement of patient and public involvement contributors who are from black and minority ethnic groups.
For #MethodologyMonday we focus on this rapid communication on the impact linked to common exclusion criteria by race and sex on trial eligibility of patients with ischemic stroke in the USA.