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Molar Pregnancy / Gestational Trophoblastic Disease (GTD)

Molar Pregnancy / Gestational Trophoblastic Disease (GTD)


Molar pregnancy

Molar pregnancy, also known as Gestational Trophoblastic Disease, is a rare disorder affecting one in 600 pregnancies. Most molar pregnancies resolve following uterine evacuation but a small number progress to malignant disease requiring chemotherapy. 

Our research in this area

  • Methods for diagnosing and monitoring molar pregnancy
  • Women’s experiences of molar pregnancy

Key publications

Category Category Keywords Year Title Abstract Actions

Journal Article

Journal Article Early pregnancy / Early pregnancy loss, Molar pregnancy / Gestational Trophoblastic Disease 2024

Proof-of-concept study: Remote capillary blood collection for hCG analysis in early pregnancy

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Journal Article

Journal Article Early pregnancy / Early pregnancy loss, Ectopic pregnancy, First-trimester miscarriage, Miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Pregnancy loss, Second-trimester miscarriage, Termination of pregnancy 2024

Statutory leave for early pregnancy loss: A comparative study

Our study identified two main approaches to leave introduced for pregnancy loss before viability: sick leave model and compassionate leave model. What works in individual jurisdictions will depend-among other factors-on the way in which leave more broadly is addressed. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

When to consult a geneticist specialising in gestational trophoblastic disease

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Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Measurement of hCG in women with gestational trophoblastic disease

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Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Appraisal of hydatidiform mole incidence and registration rates in Ireland following the establishment of a National Gestational Trophoblastic Disease Registry

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Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Morphology combined with HER2 D-DISH ploidy analysis to diagnose partial hydatidiform mole: an evaluation audit using molecular genotyping

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Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Novel scoring system provides high separation of diploidy and triploidy to aid partial hydatidiform mole diagnosis: an adaption of HER2 D-DISH for ploidy analysis

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Report

Report Early pregnancy / Early pregnancy loss, Ectopic pregnancy,Experience, Fatal fetal anomaly, First-trimester miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Second-trimester miscarriage, Termination of pregnancy 2024

PLACES | Pregnancy Loss (under 24 weeks) in Workplaces: Informing policymakers on support mechanisms

A report submitted to the Department of Children, Equality, Disability, Integration and Youth (DCEDIY) in fulfilment of the requirements of the tender for the provision of a qualitative research study to examine the workplace experiences of people dealing with pregnancy loss. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles

New guidelines from the Pathology and Genetics Working Party of the European Organisation for Treatment of Trophoblastic Diseases that describe the pathological criteria and ancillary techniques that can be used in the differential diagnosis of hydatidiform moles. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2023

Challenging gestational trophoblastic disease cases and mimics: An exemplar for the management of rare tumours

Monitoring and treatment of gestational trophoblastic disease is challenging and provides an exemplar for the management of rare tumours. Mandatory registration with a specialist unit would ensure equity of access for all patients to the myriad of supports and services required. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2022

Advances in the diagnosis and early management of gestational trophoblastic disease

Early identification of women with Gestational Trophoblastic Disease is paramount as this disorder is highly curable. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Experience, Molar pregnancy / Gestational Trophoblastic Disease 2022

Experience of women on the Irish National Gestational Trophoblastic Disease Registry

There is a knowledge gap in molar pregnancy amongst healthcare professionals which should be factored into future medical and nursing curricula. More details Read publication

Our people

Pregnancy Loss Research Group

Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, University College Cork, Fifth Floor, Cork University Maternity Hospital, Wilton, Cork, T12 YE02, Ireland,

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