Skip to main content

Publications

We aim to share information about pregnancy loss and our work within the Pregnancy Loss Research Group, in lots of different ways – browse our publications in this section.

Where possible, e.g. through dedicated project funding or IreL open access agreements, we make the full texts of our publications openly available. If you are unable to access the full texts of any of our publications, please contact us and we will send them to you.

Category Category Keywords Year Title Abstract Actions

Book chapter

Book chapter Bereavement care, Fatal fetal anomaly 2025

Delivery of unwanted news: diagnosis and assessment of needs

More details Read publication

Booklet

Booklet Recurrent miscarriage 2024

Recurrent Miscarriage Information Booklet

Recurrent Miscarriage Information and Support More details Read publication

Journal Article

Journal Article Multiple pregnancy 2024

Perinatal deaths in twin and singleton infants in Ireland: A comparison of characteristics and causes

Twin pregnancies face a 3x higher perinatal mortality risk than singleton pregnancies due to factors such as preterm birth. Our study in Ireland (2011–2022) highlights the need for updated, twin-specific guidelines & improved referral systems are essential to reduce risk. More details Read publication

Policy brief

Policy brief Early pregnancy / Early pregnancy loss, Ectopic pregnancy, Experience, First-trimester miscarriage, Impact, Miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Pregnancy loss, Recurrent miscarriage, Second-trimester miscarriage, Termination of pregnancy 2024

Pregnancy loss (<24 weeks) in workplaces: Informing policymakers on support mechanisms. PLRG Policy Brief 14

PLRG Policy Brief, September 2024 More details Read publication

Journal Article

Journal Article Fetal anomaly, Prenatal screening 2024

Non-invasive prenatal testing: Assessing the availability and accessibility of information available to the pregnant population within the Republic of Ireland

While there is apparent demand for NIPT and it is available in Ireland, there is disparity between providers on the type and quality of information they offer online. More details Read publication

Journal Article

Journal Article Ectopic pregnancy 2024

Challenges in diagnosis and management of an interstitial ectopic pregnancy

Interstitial ectopic pregnancy poses diagnostic and management complexities. Delayed diagnosis leads to elevated risks. Our case report emphasises the importance of prompt recognition and tailored interventions to enhance patient outcomes. More details Read publication

Journal Article

Journal Article Fetal anomaly, Prenatal screening 2024

Pregnant people's views and knowledge on prenatal screening for fetal trisomy in the absence of a national screening program

While pregnant women in Ireland have reasonable understanding of the interpretation of non-invasive prenatal tests for fetal aneuploidy, most were unaware of screening options. A national prenatal screening programme, including education on fetal aneuploidy, is needed. More details Read publication

Journal Article

Journal Article Impact, Recurrent miscarriage 2024

Economic and health-related quality of life impacts of receiving recurrent miscarriage care in Ireland: Exploratory analysis drawing on results from a national care experience survey

Recurrent miscarriage can amplify negative psychological outcomes, and impact work performance: 70% of study participants experienced decreased work productivity; 50% scored well below the population norm on the mental health component of the health related quality of life measure used. More details Read publication

Journal Article

Journal Article Early pregnancy / Early pregnancy loss, Molar pregnancy / Gestational Trophoblastic Disease 2024

Proof-of-concept study: Remote capillary blood collection for hCG analysis in early pregnancy

More details Read publication

Journal Article

Journal Article Ectopic pregnancy 2024

Systemic methotrexate (MTX) in early pregnancy: a retrospective study of a tertiary maternity hospital

Efficacy of medical treatment with systemic methotrexate for confirmed tubal ectopic pregnancy in our hospital is in line with national and international standards. Careful consideration should be given to treating caesarean scar pregnancy and persistent pregnancy of unknown location with systemic methotrexate. More details Read publication

Journal Article

Journal Article Pregnancy loss 2024

Methodological and practical guidance for designing and conducting online qualitative surveys in public health

Drawing and extending on the work of other researchers–as well as our own experiences of conducting online qualitative surveys with young people and adults (on topics including pregnancy loss)–we offer insights and guidance on conducting and reporting online qualitative surveys. More details Read publication

Journal Article

Journal Article Early pregnancy / Early pregnancy loss, Ectopic pregnancy, First-trimester miscarriage, Miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Pregnancy loss, Second-trimester miscarriage, Termination of pregnancy 2024

Statutory leave for early pregnancy loss: A comparative study

Our study identified two main approaches to leave introduced for pregnancy loss before viability: sick leave model and compassionate leave model. What works in individual jurisdictions will depend-among other factors-on the way in which leave more broadly is addressed. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

When to consult a geneticist specialising in gestational trophoblastic disease

More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Measurement of hCG in women with gestational trophoblastic disease

More details Read publication

Guideline

Guideline Clinical guideline(s), Stillbirth 2024

National Clinical Practice Guideline: Reduced Fetal Movements

Guideline produced for The National Women and Infants Health Programme and The Institute of Obstetricians and Gynaecologists, 2024. More details Read publication

Guideline

Guideline Clinical guideline(s), Ectopic pregnancy 2024

National Clinical Practice Guideline: The Diagnosis and Management of Ectopic Pregnancy

Guideline produced for The National Women and Infants Health Programme and The Institute of Obstetricians and Gynaecologists, 2024. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles

New guidelines from the Pathology and Genetics Working Party of the European Organisation for Treatment of Trophoblastic Diseases that describe the pathological criteria and ancillary techniques that can be used in the differential diagnosis of hydatidiform moles. More details Read publication

Journal Article

Journal Article COVID-19 2024

Effectiveness and safety of COVID-19 vaccines on maternal and perinatal outcomes: a systematic review and meta-analysis

COVID-19 vaccines are effective in preventing SARS-CoV-2 infection and related complications in pregnant women. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Novel scoring system provides high separation of diploidy and triploidy to aid partial hydatidiform mole diagnosis: an adaption of HER2 D-DISH for ploidy analysis

More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Morphology combined with HER2 D-DISH ploidy analysis to diagnose partial hydatidiform mole: an evaluation audit using molecular genotyping

More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2024

Appraisal of hydatidiform mole incidence and registration rates in Ireland following the establishment of a National Gestational Trophoblastic Disease Registry

More details Read publication

Journal Article

Journal Article Bereavement care, Experience, Impact, Neonatal death, Stillbirth 2024

Mind yourself so you can mind me; The role of parental behaviour in perinatal death on the surviving sibling’s grief

Supporting parents in their grief is a key factor for a healthy grieving process in children and must be considered when supporting families in perinatal death. More details Read publication

Journal Article

Journal Article Bereavement care, Impact, Neonatal death, Stillbirth 2024

Measuring EQ-5D-5L utility values in parents who have experienced perinatal death

Our survey study estimating the impact of perinatal death on parents’ health utility (general health and quality of life) found utility values that were 13% lower than general population values. Mental health support following perinatal bereavement is especially important. More details Read publication

Journal Article

Journal Article Impact, Neonatal death, Staff support, Stillbirth 2024

The impact of severe perinatal events on maternity care providers: a scoping review

Our scoping review shows that the impact of traumatic perinatal events on maternity care providers is severe and far reaching. Not getting adequate support from their organisation was frequently mentioned and strengthened the negative impact of the event. More details Read publication

Journal Article

Journal Article COVID-19, Perinatal pathology, Pregnancy after loss, Stillbirth 2024

SARS-CoV-2—Placental effects and association with stillbirth

During the COVID-19 pandemic a clear link between the SARS-CoV-2 virus and poor fetal outcomes was observed. In this paper, we discuss: stillbirth during COVID-19; diagnosis and link with placentitis; outcomes; vaccination; role of MDT/collaboration; management of next pregnancy. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Neonatal death, Perinatal mortality, Stillbirth 2024

A systematic review of standardised tools used in perinatal death review programmes

Our review found that there is little standardisation when it comes to perinatal mortality review tools. Guidance on structuring such tools in a standardised way is needed as part of efforts to reduce preventable perinatal deaths. More details Read publication

Report

Report Early pregnancy / Early pregnancy loss, Ectopic pregnancy,Experience, Fatal fetal anomaly, First-trimester miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Second-trimester miscarriage, Termination of pregnancy 2024

PLACES | Pregnancy Loss (under 24 weeks) in Workplaces: Informing policymakers on support mechanisms

A report submitted to the Department of Children, Equality, Disability, Integration and Youth (DCEDIY) in fulfilment of the requirements of the tender for the provision of a qualitative research study to examine the workplace experiences of people dealing with pregnancy loss. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Early pregnancy / Early pregnancy loss, Ectopic pregnancy, Fatal fetal anomaly, Miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Pregnancy loss, Stillbirth 2024

Bridging the gap between pregnancy loss research and policy and practice: insights from a qualitative survey with knowledge users

Bridging the gap between pregnancy loss research and policy and practice requires ending the silence, stigma and inequality around pregnancy loss, and using a range of tailored, accessible approaches to engage a large, diverse range of knowledge users More details Read publication

Journal Article

Journal Article COVID-19 2024

SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis

A detailed review of the evidence around rates of SARS-CoV-2 positivity in babies born to mothers with COVID-19 infection showed that these rates were low, and were more likely in women with severe disease, and confirmed that vertical transmission was possible, although rare. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly, Fetal anomaly, Termination of pregnancy, Termination of pregnancy for fetal anomalies 2023

The outcome of trisomy 18 pregnancies following the legalisation of termination of pregnancy

Our study of Trisomy 18 in pregnancy found that earlier referral to fetal medicine services enabled decision-making around whether to terminate or continue pregnancy. The findings support universal access to first trimester prenatal aneuploidy screening and both care options. More details Read publication

Journal Article

Journal Article Perinatal pathology 2023

Cytology techniques can provide insight into human placental structure including syncytiotrophoblast nuclear spatial organisation

The normal appearance of the human placenta, as seen using modern cytology techniques, is described for the first time, providing novel views of placental structures including the complex linear patterns of nuclear organisation in syncytiotrophoblast. More details Read publication

Report

Report Stillbirth 2023

Invited commentary: Exploring the complexity of stillbirth prevention: Insights from the RELEVANT Study on risk factors and implications for policy and practice

More details Read publication

Journal Article

Journal Article 2023

Factors influencing medical students’ decision to pursue a career in obstetrics and gynaecology

Clerkship experience influenced medical students’ perception of Obstetrics & Gynaecology; was more likely to be positive if they experienced direct consultant engagement and hands-on experience. Lifestyle factors, litigation and media were deterrents to considering the specialty. More details Read publication

Journal Article

Journal Article 2023

Umbilical cord milking versus delayed cord clamping in infants 28 to 32 weeks: A randomized trial

Our randomised controlled trial of umbilical cord milking versus delayed cord clamping among preterm infants born between 28 and 32 weeks' gestation found no difference in the rates of severe intraventricular hemorrhage or death. More details Read publication

Journal Article

Journal Article Pregnancy after loss 2023

Midwives’, obstetricians’, and nurses’ perspectives of humanised care during pregnancy and childbirth for women classified as high risk in high income countries: A mixed methods systematic review

Our mixed methods review of the presence of humanisation for women with high risk pregnancy/childbirth in high income countries identified complementary findings on: (i) the importance of developing a harmonised relationship with women; (ii) increased time counselling women on their choices; (iii) fear of professional reputational damage if caring outside of protocols. More details Read publication

Policy brief

Policy brief Early pregnancy / Early pregnancy loss, Ectopic pregnancy, Experience, First-trimester miscarriage, Impact, Miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Recurrent miscarriage, Second-trimester miscarriage, Stillbirth 2023

Why don't we talk about pregnancy loss? PLRG Policy Brief

PLRG Policy Brief, October 2023 More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Neonatal death, Perinatal mortality, Stillbirth 2023

A protocol for a systematic review of standardised tools used in perinatal death review programmes [version 2; peer review: 2 approved]

A protocol for a systematic review of standardised tools or frameworks used to audit perinatal deaths in middle- to high-income countries. More details Read publication

Journal Article

Journal Article Staff support 2023

The current Irish medicolegal landscape: An unsustainable trajectory

Action is required to change the course of the currently unsustainable trajectory of the Irish medicolegal landscape. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Infertility / IVF / Medically Assisted Reproduction, Recurrent miscarriage 2023

Recurrent miscarriage and infertility: A national service evaluation

Our evaluation of care provision for women/couples with RM and infertility across public and private sectors in Ireland found that, while care is largely in line with clinical practice guidelines, there is variation in counselling, imaging and surgical treatments offered. More details Read publication

Journal Article

Journal Article Stillbirth 2023

Designing a behaviour change intervention to address the behavioural risk factors for stillbirth: A study protocol [version 1; peer review: awaiting peer review]

Addressing preventable stillbirths is crucial. This study aims to design a behaviour change intervention using established behavioural science models and frameworks (COM-B and the Behaviour Change Wheel). Evidence-based & adaptable, it targets behavioural risk factors for stillbirth. More details Read publication

Policy brief

Policy brief Bereavement care, COVID-19, Early pregnancy / Early pregnancy loss, Experience, First-trimester miscarriage, Impact, Miscarriage, Recurrent miscarriage 2023

Impact of the COVID-19 pandemic on recurrent miscarriage services: More compassionate, person-centred policies and approaches within maternity services needed. PLRG Policy Brief 13

PLRG Policy Brief, July 2023 More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Fetal anomaly, Termination of pregnancy, Termination of pregnancy for fetal anomalies 2023

Fetal anomaly diagnosis and termination of pregnancy in Ireland; a service evaluation following implementation of abortion services in 2019

Our service evaluation of fetal medicine clinics in two tertiary maternity hospitals between 2019-2021 emphasises the impact of legislative barriers to abortion care–and the need for policies and services that support women's access to termination of pregnancy–for major fetal anomalies. More details Read publication

Journal Article

Journal Article Stillbirth 2023

Reply to: “The partner-an underutilized facilitator to support healthy gestational weight gain”

We agree with the comments in the response by Sparks et al. that it is important to include partners in the design of interventions to address weight management behaviours during pregnancy. Other relevant people in women’s contexts should also be considered. More details Read publication

Journal Article

Journal Article Perinatal mortality 2023

Barriers to attendance at a tertiary hospital’s perinatal mortality meeting

Barriers to attendance at perinatal mortality multi-disciplinary team meetings include: Workload and staffing levels, meeting logistics, and lack of communication and education regarding these meetings. More details Read publication

Journal Article

Journal Article COVID-19, Experience, Impact, Miscarriage, Recurrent miscarriage 2023

‘An extra level of kind of torment’: Views and experiences of recurrent miscarriage care during the initial phases of COVID-19 in Ireland—A qualitative interview study

Our analysis provides rich insights into the significant impacts that the COVID-19 pandemic has had on the way recurrent miscarriage care is provided & experienced, with important implications for early pregnancy, miscarriage & recurrent miscarriage care. Deprioritisation of miscarriage services is of particular concern. More details Read publication

Graphic Narrative

Graphic Narrative Bereavement care, Experience, Impact, Neonatal death, Perinatal mortality, Stillbirth 2023

Why my baby died

The Pregnancy Loss Research Group curated the production of a graphic narrative in collaboration with Amy Lauren, an illustrator based in Dublin, to show bereaved parents’ views and experiences of hospital processes to find out why their baby died. More details Read publication

Journal Article

Journal Article Clinical guideline(s), Multiple pregnancy 2023

Clinical practice guidelines for the antenatal management of dichorionic diamniotic twin pregnancies: a systematic review

Inconsistent guidelines for managing DCDA twin pregnancies create obstacles in antenatal care. Conflicting recommendations and gaps in guidance complicate decision-making. Clear, comprehensive guidelines are essential for optimal management. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2023

Challenging gestational trophoblastic disease cases and mimics: An exemplar for the management of rare tumours

Monitoring and treatment of gestational trophoblastic disease is challenging and provides an exemplar for the management of rare tumours. Mandatory registration with a specialist unit would ensure equity of access for all patients to the myriad of supports and services required. More details Read publication

Journal Article

Journal Article Stillbirth 2023

A systematic review of behaviour change techniques used in the context of stillbirth prevention

Preventing stillbirth requires effective behaviour change interventions. Our study found limited effects of these interventions and a focus on information provision. Further research is needed to address social influence and environmental barriers. More details Read publication

Journal Article

Journal Article Experience, Recurrent miscarriage 2023

Factors that shape recurrent miscarriage care experiences: findings from a national survey

While overall experience of recurrent miscarriage care was poor, we identified areas that could potentially improve people’s care experiences such as information provision, supportive care, communication, and care coordination across settings. More details Read publication

Policy brief

Policy brief Audit / Service evaluation, Perinatal mortality, Stillbirth 2023

Irish inquiry reports relating to perinatal deaths and pregnancy loss services: What can we learn? PLRG Policy Brief 12

PLRG Policy Brief, March 2023 More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Fatal fetal anomaly, Perinatal palliative care, Termination of pregnancy 2023

Critical discourse analysis on the influence of media commentary on fatal fetal anomaly in Ireland

There are significant misrepresentations in the information being delivered to the public on fatal fetal anomalies. Healthcare professionals need to analyse information available to the public and engage in media literacy and to develop these skills in their patients. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Infertility / IVF / Medically Assisted Reproduction, Recurrent miscarriage 2023

An examination of care received by women with recurrent miscarriage and infertility against guideline-based key performance indicators

We used guideline-based KPIs to examine care for women with recurrent miscarriage and infertility. Most KPIs were met; areas for improvement were counselling on risk factors & treatments, and access to genetic counselling, ultrasound and cytogenetics. More details Read publication

Policy brief

Policy brief Impact, Perinatal mortality, Stillbirth 2023

The impact of perinatal death on healthcare staff: A rationale for change in education, training and introduction of support systems. PLRG Policy Brief 11

PLRG Policy Brief, February 2023 More details Read publication

Journal Article

Journal Article Bereavement care, Experience, Impact, Neonatal death, Perinatal mortality, Stillbirth 2023

Bereaved parents involvement in maternity hospital perinatal death review processes: ‘Nobody even thought to ask us anything’

A respectful, flexible system that allows bereaved parents involvement in their baby's perinatal death review, and is tailored to their needs, is essential. A collaborative process can highlight clinical areas in need of change, enhance lessons learned, improve bereavement services and may prevent future deaths. More details Read publication

Guideline

Guideline Bereavement care, Clinical guideline(s), Perinatal pathology, Pregnancy loss, Stillbirth 2023

National Clinical Practice Guideline: Stillbirth - Prevention, Investigation, Management and Care

Guideline produced for The National Women and Infants Health Programme and The Institute of Obstetricians and Gynaecologists, 2023. More details Read publication

Guideline

Guideline Clinical guideline(s), Recurrent miscarriage 2023

National Clinical Practice Guideline: Recurrent Miscarriage

Guideline produced for The National Women and Infants Health Programme and The Institute of Obstetricians and Gynaecologists, 2023. More details Read publication

Guideline

Guideline Clinical guideline(s), Termination of pregnancy 2023

National Clinical Practice Guideline: Investigation and Management of Complications of Termination of Pregnancy

Guideline produced for The National Women and Infants Health Programme and The Institute of Obstetricians and Gynaecologists, 2023. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Recurrent miscarriage 2023

A national evaluation of recurrent miscarriage care services

While some good practice was identified, there was variation, e.g. in referral criteria, clinic locations, genetic counselling, recording of subsequent pregnancy outcomes. A national guideline for recurrent miscarriage is required, and services must be adequately resourced. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly, Perinatal palliative care, Termination of pregnancy for fetal anomalies 2023

Fatal fetal anomaly: Exploring experiences of women and their partners

Parents with a diagnosis of fatal fetal anomaly need consistent, well communicated, and comprehensive care, which encourages an individualised perinatal palliative care approach to meet parental needs. More details Read publication

Journal Article

Journal Article 2022

A qualitative review of challenges in recruitment and retention in obstetrics and gynecology in Ireland: The consultants’ solution based perspective

Consultants in obstetrics and gynecology have provided solutions to the career challenges they encounter, and how they affect the recruitment and retention of doctors-in-training. Evaluation of proposed changes to recruitment and training practices is needed. More details Read publication

Journal Article

Journal Article Molar pregnancy / Gestational Trophoblastic Disease 2022

Advances in the diagnosis and early management of gestational trophoblastic disease

Early identification of women with Gestational Trophoblastic Disease is paramount as this disorder is highly curable. More details Read publication

Thesis

Thesis Stillbirth 2022

Rethinking stillbirth through behaviour change

Rethinking stillbirth through behaviour change | PhD Thesis: Dr Tamara Escañuela Sánchez. More details Read publication

Policy brief

Policy brief Bereavement care, Neonatal death, Perinatal mortality, Stillbirth 2022

Bereaved parents and maternity hospital perinatal death reviews: a respectful and collaborative process is needed. PLRG Policy Brief 10

PLRG Policy Brief, December 2022 More details Read publication

Journal Article

Journal Article Stillbirth 2022

Exploring first-time mothers' experiences and knowledge about behavioural risk factors for stillbirth

Results suggest that there is a silence around stillbirth, including in antenatal care, which hinders information provision. Receiving information about stillbirth was perceived as positive to help prevention. More details Read publication

Journal Article

Journal Article Bereavement care, Impact, Stillbirth 2022

Addressing obstetricians’ awareness of compassion, communication, and self-care when caring for families experiencing stillbirth: Evaluation of a novel educational workshop using applied drama techniques

A novel educational workshop using applied drama techniques–developed collaboratively with diverse stakeholders, including people with lived experience–is an acceptable and appropriate way of training obstetricians in how to care for bereaved parents/to engage in self-care. More details Read publication

Journal Article

Journal Article Recurrent miscarriage 2022

Estimating the costs associated with the implementation of a best practice model of care for recurrent miscarriage clinics in Ireland: a cost analysis [version 1; peer review: awaiting peer review]

This study advocates for a new model of care for recurrent miscarriage clinics in Ireland and provides a set of cost estimates at the patient and healthcare system level. More details Read publication

Book chapter

Book chapter Miscarriage, Perinatal palliative care, Pregnancy loss, Spirituality, Stillbirth, Termination of pregnancy, Termination of pregnancy for fetal anomalies 2022

Perinatal death: Complex and nuanced life, love and loss

Parents are faced with complex ethical decisions following a diagnosis of FFA. For some, the most compassionate approach will include termination. A palliative care approach & comprehensive bereavement care is proposed for all babies diagnosed with a life-limiting condition. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Experience, Stillbirth 2022

Facilitators and barriers to seeking and engaging with antenatal care in high-income countries: A meta-synthesis of qualitative research

The reasons why women seek or delay attending antenatal care are multifactorial. Barriers include sociodemographic factors, difficulties navigating the health system, administrative delays, lack of flexibility and tailored care, constant change of carer and communication issues. More details Read publication

Journal Article

Journal Article Recurrent miscarriage 2022

Reproductive outcomes following recurrent first trimester miscarriage: A retrospective cohort study

This retrospective cohort study of 748 women with recurrent miscarriage showed that maternal characteristics such as age, smoking and parental karyotype are associated with subsequent reproductive outcomes. 77% of women conceived and the livebirth rate was 63%. More details Read publication

Policy brief

Policy brief 2022

The RELEVANT study: Rethinking stillbirth through behaviour change. PLRG Policy Brief 9

PLRG Policy Brief, October 2022 More details Read publication

Policy brief

Policy brief Termination of pregnancy, Termination of pregnancy for fetal anomalies 2022

Termination of pregnancy: Training and clear guidance can have a meaningful impact on services. PLRG Policy Brief 8

PLRG Policy Brief, October 2022 More details Read publication

Policy brief

Policy brief Fatal fetal anomaly, Termination of pregnancy for fetal anomalies 2022

Experiences of pregnancy with fatal fetal anomaly. PLRG Policy Brief 7

PLRG Policy Brief, October 2022 More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Bereavement care, Clinical guideline(s), Experience, Impact, Miscarriage, Recurrent miscarriage 2022

How we define recurrent miscarriage matters: A qualitative exploration of the views of people with professional or lived experience

A nuanced approach to defining recurrent miscarriage is warranted, one which is evidence-informed, recognises individual people’s needs, and considers healthcare resources. More details Read publication

Journal Article

Journal Article Fetal growth restriction 2022

Dynamic growth changes in fetal growth restriction using serial ultrasonographic biometry and umbilical artery doppler: The multicenter PORTO study

Fetuses with initial growth restriction that later outgrow this diagnosis are more likely to have healthy mothers and normal Doppler studies, and once a fetus has outgrown the 10th centile, consideration could be given to decreasing antenatal surveillance. More details Read publication

Journal Article

Journal Article Experience, COVID-19, Neonatal death, Stillbirth 2022

Multicountry study protocol of COCOON: COntinuing Care in COVID-19 Outbreak global survey of new, expectant, and bereaved parent experiences

This international study aims to understand the psychosocial impact of COVID-19 and the experiences of parents who have accessed maternity, neonatal and bereavement care services across 15 countries. More details Read publication

Journal Article

Journal Article Stillbirth 2022

Facilitators and barriers influencing weight management behaviours during pregnancy: a meta-synthesis of qualitative research

Interventions developed to promote and maintain weight management behaviours during pregnancy should consider all levels of influence over women’s behaviours, including women’s level of awareness and beliefs, experiences in antenatal care, education provision and social influence. More details Read publication

Policy brief

Policy brief Audit / Service evaluation, Recurrent miscarriage 2022

Recurrent miscarriage in Ireland: A national service evaluation. PLRG Policy Brief 4

PLRG Policy Brief, September 2022 More details Read publication

Policy brief

Policy brief Recurrent miscarriage 2022

Men and recurrent miscarriage: Urgent inclusion needed. PLRG Policy Brief 6

PLRG Policy Brief, September 2022 More details Read publication

Policy brief

Policy brief Recurrent miscarriage 2022

How we define recurrent miscarriage matters. PLRG Policy Brief 3

PLRG Policy Brief, September 2022 More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Termination of pregnancy 2022

Healthcare professionals and students’ knowledge on termination of pregnancy legislation and clinical practice: a systematic review

There is a widespread lack of knowledge of Termination of Pregnancy (TOP) legislation and clinical practice from healthcare students and staff, internationally. TOP training and education are still needed to ensure adequate care and high-quality TOP services. More details Read publication

Policy brief

Policy brief Recurrent miscarriage 2022

Exploratory analysis of the costs associated with receiving recurrent miscarriage care in Ireland. PLRG Policy Brief 5

PLRG Policy Brief, September 2022 More details Read publication

Journal Article

Journal Article COVID-19 2022

Recruitment of pregnant women to randomised trials of COVID 19 treatments, and pharmaceutical treatments received outside such trials: A research article

Even though pregnant women with COVID-19 were excluded from randomised trials in our review of observational studies, they still received unproven or ineffective treatments. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Neonatal death, Perinatal mortality, Stillbirth 2022

Perinatal mortality audits and reporting of perinatal deaths: Systematic review of outcomes and barriers

Incomplete data, lack of standardised methods &classifications, inadequate training - identified as main barriers for perinatal mortality audit. To reduce perinatal mortalities, audit cycles must be completed, implementing recommendations with continuous re-evaluation of changes. More details Read publication

Report

Report Bereavement care, Pregnancy loss 2022

National Standards For Bereavement Care Following Pregnancy Loss And Perinatal Death. Version 2

The purpose of these Standards is to enhance bereavement care services for parents who experience a pregnancy loss or perinatal death. They cover all types of pregnancy loss situations, including diagnosis of fetal anomaly that will be life-limiting or may be fatal. More details Read publication

Journal Article

Journal Article Experience, Recurrent miscarriage 2022

The experiences of men following recurrent miscarriage in an Irish tertiary hospital: A qualitative analysis

Recurrent miscarriage is a deeply emotional experience for men who describe frustration with lack of support and feeling unimportant when their partners experienced recurrent miscarriage. Dedicated support and improved information is required. More details Read publication

Journal Article

Journal Article COVID-19, Miscarriage, Neonatal death, Perinatal pathology, Stillbirth 2022

Placental tissue destruction and insufficiency from COVID-19 causes stillbirth and neonatal death From hypoxic-ischemic injury: A study of 68 cases with SARS-CoV-2 Placentitis from 12 countries

A study of 68 cases of COVID-19 related placental infection (SARS-CoV-2 Placentitis) from 12 countries shows that placental tissue injury from COVID-19 causes stillbirth and neonatal death through hypoxic-ischemic injury. More details Read publication

Journal Article

Journal Article Ethics, First-trimester miscarriage, Recurrent miscarriage 2022

Outsourcing transcription: Extending ethical considerations in qualitative research

Researchers and ethics committees should consider ethical responsibilities to ‘do no harm’ when it comes to transcriptionist wellbeing. Actions we can take as part of a research team approach include having: initial briefing, distress protocol, ongoing de-briefing. More details Read publication

Journal Article

Journal Article Clinical guideline(s), PPI, Recurrent miscarriage 2022

Developing guideline-based key performance indicators for recurrent miscarriage care: lessons from a multi-stage consensus process with a diverse stakeholder group

It is important and feasible to develop guideline-based care key performance indicators (KPIs) with a diverse stakeholder group. We developed 110 KPIs for recurrent miscarriage care using a consensus process. Our experiences may help others undertaking similar projects. More details Read publication

Journal Article

Journal Article COVID-19, Miscarriage, Neonatal death, Perinatal pathology, Stillbirth 2022

Fetal deaths in Ireland due to SARS-CoV-2 Placentitis caused by SARS-CoV-2 Alpha

COVID-19 due to SARS-CoV-2 Alpha was associated with seven fetal deaths in the Republic of Ireland in early 2021. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Experience, Molar pregnancy / Gestational Trophoblastic Disease 2022

Experience of women on the Irish National Gestational Trophoblastic Disease Registry

There is a knowledge gap in molar pregnancy amongst healthcare professionals which should be factored into future medical and nursing curricula. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly 2022

Dating ultrasounds are fundamental to modern obstetric care

Dating ultrasounds confirm viability, pregnancy number and due date. These factors are the basis of antenatal care. This study reinforces the need for routine scanning of all pregnancies in the first trimester. More details Read publication

Journal Article

Journal Article Stillbirth 2022

A protocol for a systematic review of behaviour change techniques used in the context of stillbirth prevention [version 2; peer review: 2 approved, 1 approved with reservations]

Given the modifiable nature of some risk factors for stillbirth, there is increasing interest in designing interventions to reduce these risks. We aim to identify and review these interventions to see what works or not to guide the development of future interventions. More details Read publication

Journal Article

Journal Article Stillbirth 2022

Facilitators and barriers to substance-free pregnancies in high-income countries: A meta-synthesis of qualitative research

Perceived benefits, knowledge, experiences in health care settings, and social factors all play important roles in women’s substance use behaviours. Increased clinical and community awareness is necessary to inform future prevention efforts. More details Read publication

Journal Article

Journal Article COVID-19 2022

SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis

A detailed review of the evidence around rates of SARS-CoV-2 positivity in babies born to mothers with COVID-19 infection showed that these rates were low, and were more likely in women with severe disease, and confirmed that vertical transmission was possible, although rare. More details Read publication

Book chapter

Book chapter Pregnancy loss, Stillbirth 2022

Pregnancy loss: A silent loss and challenging birth

Pregnancy loss has been a ‘silent’ and lonely experience in our Irish history. The increased recognition in civil, religious & societal approaches to pregnancy loss has provided improved awareness alongside improved overall care. More details Read publication

Journal Article

Journal Article Impact, Pregnancy after loss, Stillbirth 2022

Pregnancy after stillbirth: maternal and neonatal outcomes and health service utilization

Pregnancy after stillbirth was associated with increased surveillance and intervention - women in this study had higher rates of caesarean delivery, induction of labour, and preterm delivery than the general multiparous population. More details Read publication

Journal Article

Journal Article COVID-19, Stillbirth 2022

COVID-19 and pregnancy: A comparison of case reports, case series and registry studies

Case reports and retrospective series published early on in the COVID-19 pandemic had useful information, but overestimated maternal, fetal and neonatal complications related to COVID-19 infection when compared with later prospective registries. More details Read publication

Book chapter

Book chapter Bereavement care, Fatal fetal anomaly, Perinatal palliative care, Termination of pregnancy for fetal anomalies 2022

Birth when life is short

Birth When Life is Short – a short summary of the positive trajectory of the development of bereavement care in pregnancy loss in Ireland. More details Read publication

Thesis

Thesis Audit / Service evaluation, Experience, Neonatal death, Perinatal mortality, Stillbirth 2021

Study of methods, systems, recommendations and bereaved parents’ involvements in perinatal death reviews, inquiries and audits

Study of methods, systems, recommendations and bereaved parents’ involvements in perinatal death reviews, inquiries and audits | PhD Thesis: Dr Änne Helps. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Neonatal death, Perinatal mortality, Stillbirth 2021

National perinatal mortality audits and resultant initiatives in four countries

Challenges are common to high-income countries’ perinatal mortality audits, highlighting the need for shared learning of successful initiatives. More details Read publication

Journal Article

Journal Article Clinical guideline(s), Multiple pregnancy 2021

A protocol for a systematic review of clinical practice guidelines for the antenatal management of dichorionic diamniotic twin pregnancy [version 1; peer review: 1 approved]

Our protocol for a systematic review of clinical practice guidelines for the antenatal management of dichorionic diamniotic twin pregnancies, within high-income countries. More details Read publication

Journal Article

Journal Article Pregnancy loss, Recurrent miscarriage, Second-trimester miscarriage, Stillbirth 2021

Implementation of new cytogenetic testing regimens in pregnancy loss at a tertiary maternity hospital in Cork, Ireland

Following the introduction of new cytogenetic testing regimens at CUMH, we observed positive changes such as decreased submissions with incomplete clinical information. Improvements in sample collection and education regarding appropriate cytogenetic testing are needed. More details Read publication

Journal Article

Journal Article Bereavement care, Neonatal death, Perinatal mortality, Stillbirth 2021

Governance of maternity services: Effects on the management of perinatal deaths and bereavement services

To be effective and initiate positive changes in clinical services, documents such as incident reviews, national strategies and national reports including inquiries, need to include realistic recommendations with clear timelines and responsibilities for implementation. More details Read publication

Journal Article

Journal Article Infertility / IVF / Medically Assisted Reproduction, Recurrent miscarriage 2021

Infertility and subsequent recurrent miscarriage: Current state of the literature and future considerations for practice and research

Narrative review demonstrating women/couples with RM and infertility appear indirectly in studies evaluating investigations and treatments. High-quality studies are lacking. Furthermore, they are largely excluded from international clinical guidance and qualitative research. More details Read publication

Journal Article

Journal Article Experience, Pregnancy after loss, Stillbirth 2021

Trying to conceive: An interpretive phenomenological analysis of couples’ experiences of pregnancy after stillbirth

The experiences of trying to conceive after stillbirth impacted the couple relationships. Couples who were able to discuss their feelings with one another appeared more cohesive than those who experienced communication challenges in the aftermath of loss. More details Read publication

Journal Article

Journal Article 2021

Reference values for C-reactive protein and procalcitonin at term pregnancy and in the early postnatal period

Variability of C-reactive protein limits its clinical utility in the assessment of sepsis but procalcitonin may serve as a valuable biomarker to help rule out infection in pregnancy and postpartum. More details Read publication

Journal Article

Journal Article Termination of pregnancy 2021

Termination of pregnancy services: a year in review in a tertiary maternity hospital

Audit of 1st year of TOP in a large maternity hospital shows variation in time between mife and misoprostol administration and inconsistent management of pregnancy tissue. Clear protocols and staff education vital to ensure high-quality service and welfare of staff and women. More details Read publication

Book chapter

Book chapter Bereavement care, Perinatal palliative care 2021

Perinatal palliative care

Perinatal Palliative Care provides for optimal holistic care of a baby and family following a life-limiting diagnosis. Models of planning & care are provided to provide optimum comfort for the baby, mother & family. More details Read publication

Report

Report Bereavement care, Ectopic pregnancy, Fatal fetal anomaly, Miscarriage, Molar pregnancy / Gestational Trophoblastic Disease, Pregnancy loss, Stillbirth, Termination of pregnancy 2021

On the Implementation of the National Standards for Bereavement Care Following Pregnancy Loss and Perinatal Death

Report on the programmes of work undertaken to implement the National Standards for Bereavement Care Following Pregnancy Loss and Perinatal Death, 2016 More details Read publication

Journal Article

Journal Article Bereavement care, Staff training 2021

Development and evaluation of TEARDROP - a perinatal bereavement care training programme for healthcare professionals

Adequate perinatal bereavement care training for maternity staff is crucial. Our evaluation of the participant-centred TEARDROP workshop shows it was very well received by staff and can impact on the quality of perinatal bereavement care provided in Ireland. More details Read publication

Journal Article

Journal Article 2021

Authors’ reply to ‘Is there a role for C-reactive protein during and after labour?’

Establishment of reference values for pregnant women is dependent on the use of strict exclusion criteria. Variability in analytical methods can affect the commutability of reference values between laboratories. More details Read publication

Journal Article

Journal Article Termination of pregnancy 2021

Termination of pregnancy: Staff knowledge and training

Study shows low levels of Termination of Pregnancy (TOP) knowledge in maternity staff. Training is required to ensure the provision of a safe and effective TOP service. Findings indicate that updated and clearer clinical guidance on TOP services is also needed. More details Read publication

Journal Article

Journal Article Bereavement care, Neonatal death, Stillbirth 2021

Maternity healthcare chaplains and perinatal post-mortem support and understanding in the United Kingdom and Ireland: An exploratory study

Study with maternity healthcare chaplains identifies that perinatal post-mortem does not have any religious prohibition and that most maternity healthcare chaplains have been asked about perinatal post-mortem by bereaved parents. More details Read publication

Journal Article

Journal Article COVID-19 2021

Early pregnancy in the Emergency Department and the effect of COVID-19

COVID-19 changed the way in which women sought guidance and accessed services in early pregnancy. During the first wave in 2020, there was a 38% decrease in women attending the emergency department, and 16% increase in women contacting the department for advice. More details Read publication

Policy brief

Policy brief Clinical guideline(s), Recurrent miscarriage 2021

Clinical practice guidelines for recurrent miscarriage in high-income countries: a systematic review. PLRG Policy Brief 2

PLRG Policy Brief, June 2021 More details Read publication

Journal Article

Journal Article 2021

Influence of cost on contraceptive choices amongst university students

Students often rely on unreliable or user-dependent methods of contraception. Our study has demonstrated that cost influences contraceptive choice with nearly half of the women surveyed stating they would change contraception if cost was removed. More details Read publication

Journal Article

Journal Article Clinical guideline(s), Recurrent miscarriage 2021

Clinical practice guidelines for recurrent miscarriage in high-income countries: a systematic review

Greater efforts are required to improve the quality of evidence underpinning clinical guidelines for recurrent miscarriage, the rigour of their development and the inclusion of multi-disciplinary perspectives, including those with lived experience. More details Read publication

Journal Article

Journal Article Miscarriage 2021

Assessing the concordance and accuracy between hospital discharge data, electronic health records, and register books for diagnosis of inpatient admissions of miscarriage: A retrospective linked data study

A very good level of agreement for diagnosis of hospitalisations of miscarriage was found among three hospital sources from January to June 2017 in Ireland. However, discrepancies were found when classifying the different types of miscarriage between the three data sources. More details Read publication

Guideline

Guideline Clinical guideline(s), COVID-19 2021

COVID-19 Infection: Guidance for Maternity Services

Guideline produced for The Institute of Obstetricians and Gynaecologists, 2021. More details Read publication

Journal Article

Journal Article Multiple pregnancy 2021

A comparative study of two immunoassays of maternal placental growth factor

A secondary subgroup analysis of placental growth factor levels in women with dichorionic twin pregnancy demonstrated poor concordance between two immunoassays. This highlights the importance of developing validated clinical cut-offs for automated immunoassay. More details Read publication

Policy brief

Policy brief 2021

The definition of stillbirth in Ireland: A rationale for change. PLRG Policy Brief 1

PLRG Policy Brief, April 2021 More details Read publication

Journal Article

Journal Article 2021

Risk perception on the labour ward: A mixed methods study

Risk, and the terminology around risk, is a challenge for staff in maternity hospitals, and better workplace strategies are needed to train and support staff. More details Read publication

Journal Article

Journal Article Bereavement care, Experience, Fatal fetal anomaly 2021

Experiences of volunteers supporting parents following a fatal fetal anomaly diagnosis

Volunteers feel comfortable in their peer support role to bereaved parents. However, there is a need for education and collaborative working between health care professionals and volunteers to assist them in supporting bereaved parents. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Stillbirth 2021

Stillbirth and risk factors: an evaluation of Irish and UK websites

We reviewed 92 websites aimed at pregnant women in Ireland and the UK, and found that they were a poor source for information related to stillbirth. More details Read publication

Journal Article

Journal Article Experience, Fatal fetal anomaly, Staff support, Termination of pregnancy 2021

Fetal medicine specialist experiences of providing a new service of termination of pregnancy for fatal fetal anomaly: a qualitative study

The implementation of termination services for fatal fetal anomaly is complex, challenging and requires institutional support. More details Read publication

Journal Article

Journal Article COVID-19 2021

Haemostatic and thrombo-embolic complications in pregnant women with COVID-19: a systematic review and critical analysis

Coagulopathy and thromboembolism are both increased in pregnancies affected by COVID-19 infection. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, First-trimester miscarriage, Miscarriage, Second-trimester miscarriage 2021

Reproductive health knowledge about miscarriage: A cross-sectional study of university students

This cross-sectional study of 746 university students demonstrates a lack of knowledge about miscarriage. Heavy bleeding, cramping and pain were identified as common features for miscarriage; however, knowledge of type of management, and diagnostic tests available was poor. More details Read publication

Journal Article

Journal Article Staff support 2021

Medicine, media and the law: The effect on training in obstetrics and gynaecology

The influence of media and the threat of litigation has a negative effect on the speciality of Obstetrics and Gynaecology, with an impact on recruitment and retention of trainees and a lack of support during specialist training. More details Read publication

Journal Article

Journal Article 2021

Forever connected: The lifelong biological consequences of fetomaternal and maternofetal microchimerism

During pregnancy there is bi-directional trafficking of fetal cells and DNA between mother and fetus, leading to persistence of cellular material, which has implications for future development, health and disease. More details Read publication

Journal Article

Journal Article COVID-19 2021

SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19

We present a case of third trimester pregnancy with SARS-CoV-2 infection and reduced fetal movements. Placental histology showed SARS-CoV-2 placentitis that may be a marker of potential vertical transmission, possibly causing fetal compromise through placental injury. More details Read publication

Journal Article

Journal Article Stillbirth 2020

A review of stillbirth definitions: A rationale for change

Study shows that with improving survival rates for periviable infants, the stillbirth definition in Ireland should be reviewed to include to ?22 weeks’ gestation and ?400?g in line with improved medical developments. More details Read publication

Journal Article

Journal Article Multiple pregnancy 2021

A prospective study of placental growth factor in twin pregnancy and development of a dichorionic twin pregnancy specific reference range

Placental growth factor (PlGF) levels in dichorionic twin pregnancy differ significantly between women that will later develop pre-eclampsia and those that will not. This study provides specific reference ranges for PlGF in twin pregnancy. More details Read publication

Thesis

Thesis Awareness / Knowledge, Bereavement care, Experience, Fatal fetal anomaly, Perinatal palliative care, Staff support, Staff training, Termination of pregnancy 2020

Experiences of pregnancy with major fetal anomalies

Experiences of pregnancy with major fetal anomalies | PhD Thesis: Dr Stacey Power Walsh. More details Read publication

Journal Article

Journal Article Experience 2020

An exploration of women's experience of taking part in a randomized controlled trial of a diagnostic test during pregnancy: A qualitative study

Women are generally interested and positively inclined to participate in research during pregnancy. The potential of risk is an important consideration. Information and support by both researchers and clinicians are paramount in aiding women's understanding of a research trial. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2020

Small for gestational age infants and the association with placental and umbilical cord morphometry: a digital imaging study

This study identified which morphometric measurements in combination are associated with SGA infants using digital imaging of the placenta. The morphometric measurements at delivery most strongly associated with SGA infants were placental weight and placental surface area. More details Read publication

Guideline

Guideline Clinical guideline(s), Fatal fetal anomaly, Termination of pregnancy for fetal anomalies 2020

Interim Clinical Guidance: Pathway for Management of Fatal Fetal Anomalies and/or Life-Limiting Conditions Diagnosed During Pregnancy - Termination of Pregnancy

Guideline produced for The Institute of Obstetricians and Gynaecologists, 2020. More details Read publication

Journal Article

Journal Article Bereavement care, Impact, Neonatal death, Perinatal mortality, Stillbirth 2020

Impact of bereavement care and pregnancy loss services on families: Findings and recommendations from Irish inquiry reports

Personalised perinatal bereavement care helps families to cope with their loss. Immediate bereavement support must be offered to families by expert maternity staff. Families and relevant clinical staff should be involved in perinatal inquiries. More details Read publication

Book

Book Pregnancy after loss 2020

Different baby, different story: Pregnancy and parenting after loss

Pregnancy after prenatal or infant loss can be a lonely and frightening time, but through stories of both pain and healing, the authors show how to navigate the exciting but choppy waters of a subsequent pregnancy. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, First-trimester miscarriage 2020

The general populations’ understanding of first trimester miscarriage: a cross sectional survey

Less than 3 in 10 people who took part in our nationally representative survey were aware of the incidence of miscarriage. Family, friends and the internet were the main knowledge sources: less than 1 in 6 people engaged with healthcare providers for miscarriage information. More details Read publication

Journal Article

Journal Article Clinical guideline(s), Recurrent miscarriage 2020

A protocol for a systematic review of clinical practice guidelines for recurrent miscarriage [version 3; peer review: 3 approved, 1 approved with reservations]

Our identification and review of published clinical guidelines for recurrent miscarriage in high-income countries will be a valuable first step in informing efforts to improve recurrent miscarriage care. More details Read publication

Journal Article

Journal Article COVID-19 2020

Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis

Risk of neonatal infection with COVID-19 by delivery route, infant feeding and mother-baby interaction. Neonatal COVID-19 infection is uncommon, rarely symptomatic, and the rate of infection is no greater when the baby is born vaginally, breastfed or remains with the mother. More details Read publication

Journal Article

Journal Article 2020

Maternity care providers’ involvement in research

Half of maternity care providers in our study reported never conducting research. Participants agreed that research is important to maintain care quality. Medical staff were more likely to report feeling competent to undertake research compared to midwives. More details Read publication

Journal Article

Journal Article Audit / Service evaluation, Neonatal death, Perinatal mortality, Stillbirth 2020

Perinatal mortality audits and reviews: Past, present and the way forward

To achieve a reduction in the number of stillbirths and neonatal deaths, it is crucial to ensure that the perinatal mortality audit and review cycle is completed with implementation and re-evaluation of recommended changes in maternity services. More details Read publication

Journal Article

Journal Article Neonatal death, Pregnancy loss, Stillbirth 2020

Education priorities for voluntary organisations supporting parents experiencing perinatal loss: a Delphi survey

A standardised approach is necessary to develop an education day that is responsive to the learning needs of volunteers supporting bereaved parents. More details Read publication

Journal Article

Journal Article Bereavement care, Pregnancy after loss, Stillbirth 2020

The RESPECT Study for consensus on global bereavement care after stillbirth

Consensus on a set of eight evidence-based core principles for bereavement care after stillbirth was established. Highest quality bereavement care should be enabled through training of healthcare staff to reduce stigma and establish respectful care. More details Read publication

Journal Article

Journal Article Impact, Infertility / IVF / Medically Assisted Reproduction, Miscarriage 2020

Stress and the impact on the outcome of medically assisted reproduction

We assessed the impact of perceived psychological stress on conception and miscarriage rates after medically assisted reproduction (MAR) through a survey. There were no differences in conception rates. Women with a self-reported stressful job had higher rates of miscarriage. More details Read publication

Journal Article

Journal Article Staff support 2020

Interventions to improve wellbeing among obstetricians and midwives at Cork University Maternity Hospital

Doctors-in-training and midwives in our study experienced high levels of burnout and compassion fatigue. End-of-shift meetings for midwives and team bonding sessions for doctors may positively impact on wellbeing, but are not feasible for implementation in their current format. More details Read publication

Journal Article

Journal Article Multiple pregnancy 2020

The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort

A retrospective cohort study of maternal & perinatal outcomes in multiple pregnancy found that age >40, nulliparity, donor oocyte & obstetric cholestasis increased risk of hypertensive disorders. This in turn increased risk of iatrogenic late prematurity & neonatal hypoglycemia. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly, Perinatal mortality 2020

The incidence of fatal fetal anomalies associated with perinatal mortality in Ireland

Only 42% of perinatal deaths could be classified as a fatal fetal anomaly in accordance with the Health (Regulation of Termination of Pregnancy) Bill 2018 highlighting the complexity of these cases/multiorgan system anomalies. More details Read publication

Journal Article

Journal Article Neonatal death, Perinatal mortality, Pregnancy loss, Stillbirth 2020

Irish inquiry reports relating to perinatal deaths and pregnancy loss services

A collaborative and standardised inquiry process ensures that all relevant issues are identified, recommendations are implemented and essential lessons are learned. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2020

Antenatal detection of abnormal placental cord insertion across different trimesters: A prospective cohort study

Our prospective cohort study compared antenatal ultrasound detection of abnormal placental cord insertion across trimesters vs delivered placental classification. Sensitivity & specificity were highest in 2nd trimester, with optimal agreement with postnatal classification. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly, Perinatal palliative care 2019

A retrospective review of the Perinatal Palliative Care (PPC) Programme at Cork University Maternity Hospital (CUMH)

Audit of implementation of the National Standards for Bereavement Care following Pregnancy Loss and Perinatal Death at a tertiary maternity hospital finds overall high level of implementation, with areas for improvement noted, such as documentation and staff education programmes. More details Read publication

Thesis

Thesis Impact, Neonatal death, Staff support, Staff training, Stillbirth 2019

The impact of intrapartum fetal death and other serious adverse perinatal events on healthcare professionals and the maternity services

The impact of intrapartum fetal death and other serious adverse perinatal events on healthcare professionals and the maternity services | PhD Thesis: Dr Karen McNamara. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2019

Role of 2-dimensional ultrasound imaging in placental and umbilical cord morphometry: Literature and pictorial review

This literature review examines the use of 2D ultrasound as a tool to measure and assess placental and umbilical cord morphometry as a screening tool for high risk pregnancies. More details Read publication

Journal Article

Journal Article Stillbirth 2019

Modifiable risk factors for stillbirth: a literature review

Smoking, alcohol, illicit drugs and medical drugs, high BMI, attendance at antenatal care and sleeping position are the main modifiable risk factors with a behavioural component that have been associated with a higher risk of stillbirth. More details Read publication

Journal Article

Journal Article Multiple pregnancy 2019

A double dilemma: treatment of stage IV fetal twin-twin transfusion syndrome in the setting of maternal recurrent venous thromoembolism: a case report

Through expert assessment of clinical complications, we demonstrate how complex high-risk and challenging medical scenarios can be successfully managed, with assistance from the local, national and international expertise in time-critical situations. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Fatal fetal anomaly, Termination of pregnancy, Termination of pregnancy for fetal anomalies 2019

Critical discourse analysis of the joint committee meetings on the eighth amendment of the constitution of Ireland

The framing of the discourse throughout the meetings of the Joint Committee on the Eighth Amendment of the Constitution likely influenced members’ knowledge, perception, and understanding of key issues, consequently impacting the development of the legislation introduced in 2019. More details Read publication

Journal Article

Journal Article Neonatal death, Perinatal mortality, Stillbirth 2019

The perceived effect of serious adverse perinatal events on clinical practice. Can it be objectively measured?

We identified some statistically significant changes in labour ward clinical activity in the 28 days following five out of six serious adverse perinatal events; the change in activity could not be attributed directly to the preceding adverse event. More details Read publication

Journal Article

Journal Article Miscarriage 2019

Risk factors for miscarriage among women attending an early pregnancy assessment unit (EPAU): a prospective cohort study

Our prospective cohort study explored risk factors among 293 women who attended an Early Pregnancy Assessment Unit in Ireland in 2012. Advanced maternal age, history of recurrent miscarriage, and lack of emotional wellbeing were risk factors for having a subsequent miscarriage. More details Read publication

Thesis

Thesis Awareness / Knowledge, Experience, Impact, Miscarriage 2019

An exploration of miscarriage in the Republic of Ireland: incidence, management, risk factors, interventions, and populations’ knowledge

An exploration of miscarriage in the Republic of Ireland: incidence, management, risk factors, interventions, and populations’ knowledge | PhD Thesis: Dr Indra San Lázaro Campillo. More details Read publication

Journal Article

Journal Article Recurrent miscarriage 2019

A review of reproductive outcomes of women with two consecutive miscarriages and no living child

A causative factor was identified in 29% of women with two consecutive miscarriages in our study. 82% had a subsequent pregnancy, with 73% achieving a live birth. We suggest that supportive care is the single most effective therapy for women with two consecutive miscarriages. More details Read publication

Journal Article

Journal Article Second-trimester miscarriage 2019

Subsequent pregnancy outcomes following second trimester miscarriage—A prospective cohort study

Women with second-trimester miscarriage in our study had a notable rate of recurrence (6.3%). Second-trimester miscarriage is a risk factor for adverse pregnancy outcomes. It merits close observation during pregnancy, particularly women with a history of periviable loss. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2019

Rounded intraplacental hematoma - A high risk placental lesion as illustrated by a prospective study of 26 consecutive cases

A rounded intraplacental hematoma (RIH) is a recently described anomaly of the placenta. This is the first study to identify and collect RIHs using standardised pathological criteria and shows an association between RIHs and stillbirth. More details Read publication

Journal Article

Journal Article Bereavement care, Staff support, Staff training, Stillbirth 2019

Applied drama techniques in obstetrics: development of a novel educational workshop to improve obstetrician awareness of compassion, communication and self-care around the time of stillbirth

Trainee participation in a novel educational workshop, using applied drama techniques, resulted in a subjective improvement in key skills that obstetricians should have when caring for and communicating with parents around the time of stillbirth. More details Read publication

Journal Article

Journal Article Miscarriage 2019

Miscarriage hospitalisations: a national population-based study of incidence and outcomes, 2005–2016

In a nationwide population-based study of 50,538 hospitalisations with a diagnosis of early miscarriage in all acute maternity hospitals in Ireland during 2005–2016, we found that early miscarriage hospitalisations became 19% less common but the risk of blood transfusion doubled. More details Read publication

Journal Article

Journal Article Impact, Spirituality, Pregnancy loss 2019

Pregnancy loss: A disturbing silence and theological wilderness

Pregnancy loss is a deeply challenging spiritual and theological reality for bereaved parents. Faith communities are challenged to engage at a deeper level with this often silent wilderness experience with greater liturgical and pastoral provision and robust reflection. More details Read publication

Journal Article

Journal Article Bereavement care, Experience, Fatal fetal anomaly 2019

Anencephaly; the maternal experience of continuing with the pregnancy. Incompatible with life but not with love

Anencephaly, a fatal fetal anomaly in pregnancy, is devastating for parents and termination is often considered best management. Continuing the pregnancy before saying goodbye may be a healing and positive alternative to early termination for some women. More details Read publication

Journal Article

Journal Article Bereavement care, Pregnancy loss 2019

The electronic record and the value of an alert symbol

The introduction of a specific pregnancy loss alert symbol on electronic records would benefit clinical practice greatly. Further education and training in navigating this record is needed so that important information can be easily sought out and to improve care. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Fatal fetal anomaly, Termination of pregnancy, Termination of pregnancy for fetal anomalies 2019

An assessment of UCC students’ knowledge of fatal fetal anomaly and termination of pregnancy for fetal abnormality

Our study highlights a gap in university student knowledge around fatal fetal anomaly (FFA) and termination of pregnancy for fetal abnormality (TOPFA). More readily available, and accurate, public health and college education campaigns are needed. More details Read publication

Journal Article

Journal Article PPI, Pregnancy loss, Stillbirth 2019

Parents and clinicians: partners in perinatal bereavement research – experiences from the International Stillbirth Alliance Conference 2017

In this commentary, we highlight the value of: partnership between bereaved patients and clinicians, creativity as a unifying expression of grief and to facilitate learning, collaboration with global stakeholders, and meaningful patient/public engagement in research. More details Read publication

Journal Article

Journal Article Stillbirth 2019

Beyond the headlines: Fetal movement awareness is an important stillbirth prevention strategy

Shared decision-making and a sensible approach to risk assessment, with prudent use of obstetric interventions, should save lives without causing harm. More details Read publication

Guideline

Guideline Clinical guideline(s), Fatal fetal anomaly, Perinatal palliative care 2019

Pathway for Management of Fatal Fetal Anomalies and/or Life-Limiting Conditions Diagnosed During Pregnancy - Perinatal Palliative Care

Guideline produced for The National Women and Infants Health Programme and The Institute of Obstetricians and Gynaecologists, 2019. More details Read publication

Journal Article

Journal Article Experience, Pregnancy loss 2018

Patients’ perception of privacy and confidentiality in the emergency department of a busy obstetric unit

The layout of emergency departments (EDs) in maternity units should provide privacy and confidentiality for women accessing services. Our ED was renovated to improve privacy. Women surveyed before and after the renovation reported increased satisfaction with privacy. More details Read publication

Guideline

Guideline Clinical guideline(s), Termination of pregnancy 2018

Interim Clinical Guidance: Termination of Pregnancy under 12 weeks

Guideline produced for The Institute of Obstetricians and Gynaecologists, 2018. More details Read publication

Journal Article

Journal Article Ectopic pregnancy 2018

Ectopic pregnancy hospitalisations: A national population-based study of rates, management and outcomes

This population-based study of over 12,000 hospitalisations found that the incidence rate of hospitalisations for ectopic pregnancy increased during 2005-2016; the overall incidence was 15.1/1000 deliveries. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Miscarriage 2018

University students' awareness of causes and risk factors of miscarriage: a cross-sectional study

This cross-sectional study illustrates that common misunderstandings still prevail regarding the etiology of miscarriage, suggesting a deficiency in formal information and access to information related to reproductive health. More details Read publication

Thesis

Thesis Experience, Pregnancy after loss, Stillbirth 2018

Experiences of couples in pregnancy after stillbirth: an interpretative phenomenological analysis

Experiences of couples in pregnancy after stillbirth: an interpretative phenomenological analysis | PhD Thesis: Dr Margaret Murphy More details Read publication

Journal Article

Journal Article 2018

Placental growth factor: A review of literature and future applications

Placental growth factor (PlGF) is highly expressed during pregnancy and correlates well with placental function. Quantification of PlGF and its specific receptors may have utility as a diagnostic marker of placental disease or as an indicator of adverse pregnancy outcomes. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Fatal fetal anomaly, Termination of pregnancy 2018

An assessment of the general public's knowledge of fatal fetal anomalies

There is a lack of accurate knowledge on fatal fetal anomaly, its classification, diagnosis, survival, and supports available following a diagnosis of fatal fetal anomaly among the general public. This highlights the need for improved health information about fatal fetal anomaly. More details Read publication

Journal Article

Journal Article Experience 2018

The pregnancy experience: a mixed methods analysis of women's understanding of the antenatal journey

Women have varied experiences of antenatal care, with positive and negative aspects of care reported. Topics of poor knowledge are highlighted, particularly in women who have not had a baby before, and regarding the postnatal period. More details Read publication

Journal Article

Journal Article Experience, Impact, Neonatal death, Staff support, Stillbirth 2018

Intrapartum fetal death and doctors: a qualitative exploration

Obstetricians are profoundly and negatively affected by a personal involvement with an intrapartum death. Effective emotional support interventions for all obstetricians are needed. More details Read publication

Journal Article

Journal Article Ectopic pregnancy, Experience 2018

Irish women’s experience of Ectopic pregnancy

In this qualitative study, 7 women who experienced ectopic pregnancy were interviewed to gain insight into their experience. Key themes include treatment options, scans, bereavement counselling, outpatient care, reservations about future fertility and conception. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly 2018

A five year review of fatal fetal anomalies in a large Irish tertiary maternity hospital

This study reviewed 179 Irish women who received a diagnosis of fatal fetal anomaly (FFA) in 2012-16. Most common FFA diagnoses were cranial anomalies and aneuploidy. 49 women had an abortion for FFA in other countries. Women diagnosed with FFA require specialised care. More details Read publication

Journal Article

Journal Article Impact, Stillbirth 2018

The impact of stillbirth on bereaved parents: A qualitative study

Stillbirth has a lasting and profound impact on bereaved parents. Parents identified maintaining hope, importance of the personhood of the baby, protective care and relationships (personal and professional) in their experience of stillbirth. More details Read publication

Journal Article

Journal Article Neonatal death, Stillbirth 2018

Intrapartum fetal deaths and unexpected neonatal deaths in the Republic of Ireland: 2011 - 2014; a descriptive study

The corrected intrapartum fetal death rate for 2012 to 2014 was 0.16 per 1000 births. We were unable to identify if any of these deaths could have been prevented. A more formal confidential inquiry based system is necessary to fully appraise these cases. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Stillbirth 2018

The public awareness of stillbirth: an Irish population study

Irish population study shows low public awareness of stillbirth incidence, risk factors and causes. More details Read publication

Journal Article

Journal Article Pregnancy after loss, Stillbirth 2018

Care in subsequent pregnancies following stillbirth: an international survey of parents

More support for providing quality care in pregnancies after stillbirth is needed. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2017

Abnormal placental cord insertion and adverse pregnancy outcomes: a systematic review and meta-analysis

Our systematic review of the association of adverse pregnancy outcomes with abnormal placental cord insertion shows an increased risk of emergency Caesarean section, but this is based on a small number of studies & further research is required. More details Read publication

Journal Article

Journal Article Infertility / IVF / Medically Assisted Reproduction 2017

Oocyte donation pregnancies - Non-disclosure of oocyte recipient status to obstetric care providers and perinatal outcomes

This study examined disclosure rates of oocyte donation among pregnant women to their healthcare provider, and subsequent rates of perinatal complications. One third of women did not disclose their oocyte recipient status. 28% had hypertension in pregnancy. More details Read publication

Journal Article

Journal Article Miscarriage, Second-trimester miscarriage 2017

Psychological and support interventions to reduce levels of stress, anxiety or depression on women’s subsequent pregnancy with a history of miscarriage: an empty systematic review

Our ‘empty’ systematic review highlights the need for randomised controlled studies to assess the effect of interventions to reduce stress in pregnant women with a history of miscarriage. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly, Pregnancy loss 2017

Maternity ultrasound in the Republic of Ireland 2016; A review

This study highlights the lack of development in Irish maternity ultrasound services over the last decade. Substantial investment by health care policy makers is urgently needed. More details Read publication

Journal Article

Journal Article Impact, Pregnancy after loss, Stillbirth 2017

Parents’ concerns about future pregnancy after stillbirth: a qualitative study

Stillbirth has far-reaching and contrasting effects on parents. Mothers in our study wished to plan a future pregnancy while fathers were reluctant to consider any pregnancies. Additional appointments at the maternity hospital were considered crucial to provide reassurance. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2017

Abnormal placental cord insertion and adverse pregnancy outcomes: Results from a prospective cohort study

Digital imaging provided objective measurements of placental cord insertions, with abnormal insertions significantly associated with an increased risk of SGA and low birth weight. More details Read publication

Journal Article

Journal Article Experience, Spirituality, Stillbirth 2017

The spiritual and theological challenges of stillbirth for bereaved parents

Stillbirth has a considerable spiritual impact on bereaved parents. Spiritually, parents described searching for meaning, maintaining hope and questioning core beliefs. The faith of most parents was challenged and most not receiving adequate spiritual care in hospital. More details Read publication

Journal Article

Journal Article Experience, Spirituality, Stillbirth 2017

Stillbirth and suffering in Ireland: A theological reflection from healthcare chaplaincy

Stillbirth is an immensely challenging spiritual reality for parents and for healthcare chaplains. Using Green’s theological spiral and thick descriptors, theological engagement, pastoral tenderness and empathic presence are key attributes for spiritual care following stillbirth. More details Read publication

Journal Article

Journal Article Stillbirth 2017

Changing trends in unexplained stillbirth

Approximately a third of stillbirths are classified as unexplained. Our study illustrates that clinical-pathological correlation and discussion at multi-disciplinary team meetings improves classification. Improvements in classification will result in better patient care. More details Read publication

Journal Article

Journal Article Stillbirth 2017

A comparison of stillbirth cause of death using five international classification systems

We observed varying levels of concordance between a selection of international stillbirth classification systems. The use of varying classification systems limits the potential for improvement in understanding stillbirth and its causes. More details Read publication

Journal Article

Journal Article Experience, Miscarriage, Recurrent miscarriage 2017

Experience of miscarriage: an interpretative phenomenological analysis

This study of men and women’s experience with miscarriage involved interviewing 16 participants. Six major themes around experience of miscarriage were identified. Key findings include a need for increased awareness of miscarriage and to prioritise investigating miscarriage. More details Read publication

Journal Article

Journal Article Recurrent miscarriage 2017

Prevalence of anti nuclear antibodies in primary and secondary recurrent miscarriage

In our cohort, antinuclear antibody positivity was not significantly more prevalent in patients with recurrent miscarriage than in the control population. More details Read publication

Journal Article

Journal Article Multiple pregnancy, Neonatal death, Stillbirth 2017

Death of one twin during the perinatal period: An interpretative phenomenological analysis

Parents with a diagnosis of fetal anomaly in twin pregnancies were not prepared for the complications they experienced in pregnancy. Clear and appropriate information in relation to perinatal palliative care should be provided to parents. More details Read publication

Journal Article

Journal Article Impact, Neonatal death, Staff support, Stillbirth 2017

Healthcare professionals' response to intrapartum death: a cross-sectional study

82% of healthcare professionals received no training in dealing with intrapartum death. 94% had no education on self-care strategies. Despite it being desired by most (80%), debriefing was offered to just 11% of healthcare professionals who were involved in an intrapartum death. More details Read publication

Journal Article

Journal Article Bereavement care, Stillbirth 2017

Communication skills in Obstetrics: what can we learn from bereaved parents?

Communication in obstetrics matters. Study identifies that language used, sensitivity and diversionary techniques impact negatively when bad news is communicated in the obstetric setting. More details Read publication

Journal Article

Journal Article Impact, Spirituality, Stillbirth, Staff support 2016

The place of faith for consultant obstetricians following stillbirth: A qualitative exploratory study

Obstetricians experience inner conflict between their faith and professional practice when dealing with stillbirth. Study highlights an experienced incongruence between personal faith and professional practice when obstetricians are faced with the death of a baby. More details Read publication

Journal Article

Journal Article Second-trimester miscarriage 2016

The postnatal morbidity associated with second-trimester miscarriage

We assessed complications in women with second trimester pregnancy loss. Their management is complicated by high rates of morbidity requiring medical intervention. Awareness of these risks should inform clinical practice. More details Read publication

Report

Report Bereavement care, Pregnancy loss 2016

National Standards For Bereavement Care Following Pregnancy Loss And Perinatal Death

The purpose of these Standards is to enhance bereavement care services for parents who experience a pregnancy loss or perinatal death. They cover all types of pregnancy loss situations, including diagnosis of fetal anomaly that will be life-limiting or may be fatal. More details Read publication

Journal Article

Journal Article Bereavement care, Stillbirth 2016

Caring for parents at the time of stillbirth: How can we do better?

Parents of stillborn babies need recognition of the importance of their baby’s death and the care they receive must reflect this by providing a professional bereavement service through kind, empathic and sensitive interactions at every stage, throughout their whole experience. More details Read publication

Journal Article

Journal Article Awareness / Knowledge, Neonatal death, Stillbirth 2016

Reaction on Twitter to a cluster of perinatal deaths: A mixed method study

Twitter activity provides a useful insight into attitudes towards health-related events. The role of the media in influencing opinion is well-documented and this study highlights the challenges that clinicians face in light of an obstetric media scandal. More details Read publication

Journal Article

Journal Article Experience 2016

Women's experience of maternal morbidity: a qualitative analysis

Healthcare providers should ensure that women who experience a pregnancy-related complication are fully debriefed and have sufficient information on the complication, including ongoing care and expectations, prior to discharge. More details Read publication

Journal Article

Journal Article Stillbirth 2016

Perinatal outcomes of reduced fetal movements: a cohort study

A prospective cohort study of women presenting with reduced fetal movements (RFM) were followed to compare pregnancy outcomes with a control group. Women with RFM were more likely to be nulliparous, admitted and/or induced. Clinical implications of RFM requires more attention. More details Read publication

Thesis

Thesis Awareness / Knowledge, Bereavement care, Experience, Neonatal death, Perinatal mortality, Stillbirth 2016

Causes and consequences of pregnancy loss and perinatal death

Causes and consequences of pregnancy loss and perinatal death | PhD Thesis: Dr Sarah Meaney. More details Read publication

Journal Article

Journal Article Bereavement care, Spirituality, Staff support, Staff training, Stillbirth 2016

The provision of spiritual and pastoral care following stillbirth in Ireland: a mixed methods study

Stillbirth is a significant challenge for maternity healthcare chaplains in their personal belief and faith as they provide care. Further specialist training and support is required for chaplains in stillbirth care. More details Read publication

Guideline

Guideline Clinical guideline(s) 2016

Clinical Practice Guideline: The Management of Hypertension in Pregnancy

Guideline produced for the Institute of Obstetricians and Gynaecologists and the Health Service Executive, 2016. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2016

The role of perinatal pathology in the investigation of stillbirth

An unexplained stillbirth may simply be an uninvestigated one. With specialist pathology services, and an increase in postmortem investigations, there has been a significant decrease in the number of stillbirths whose cause of death is unexplained. More details Read publication

Journal Article

Journal Article 2016

Perinatal determinants of D-dimer levels in a cross-sectional study of low risk pregnant women

There are some significant differences in D-dimer levels when certain perinatal determinants are examined. This work supports previously published recommended D-dimer levels for the diagnosis of VTE in pregnancy. More details Read publication

Journal Article

Journal Article Impact, Stillbirth 2016

Stillbirths: economic and psychosocial consequences

Stillbirth reduction remains a global health priority. The economic costs of stillbirth are high for families, communities and society and are largely borne by families. More details Read publication

Journal Article

Journal Article Second-trimester miscarriage, Termination of pregnancy 2016

Neonatal and maternal outcomes following midtrimester preterm premature rupture of the membranes: a retrospective cohort study

This study provides useful and contemporary data on midtrimester preterm premature rupture of membranes. Whilst fetal and neonatal mortality is high, long-term survival is not impossible. The increased risk of maternal morbidity necessitates close surveillance. More details Read publication

Journal Article

Journal Article Pregnancy loss 2016

Development of a mobile health application for those who have experienced pregnancy loss

We created a website and mobile app to share evidence-based information on pregnancy loss. The app also allows users to record their experience of pregnancy loss. Data collected from app users has the potential to inform evidence based practice in the future. More details Read publication

Thesis

Thesis Impact, Spirituality, Stillbirth, Staff support 2016

The spiritual and professional impact of stillbirth

The spiritual and professional impact of stillbirth | PhD Thesis: Dr Daniel Nuzum. More details Read publication

Journal Article

Journal Article Impact, Miscarriage, Pregnancy after loss, Termination of pregnancy 2015

Previous pregnancy loss has an adverse impact on distress and behaviour in subsequent pregnancy

Women with previous miscarriages or terminations have higher levels of anxiety, depression, stress, and altered behaviours in a subsequent pregnancy, confirming psychological implications of early pregnancy loss. More details Read publication

Journal Article

Journal Article Experience, Neonatal death, Stillbirth 2015

Parental decision making around perinatal autopsy: a qualitative investigation

Parents’ decision-making regarding autopsy is profoundly affected by their emotional response to stillbirth. Clinicians and other health professionals may play a key role, especially if they can address parental concerns regarding the invasiveness of the autopsy procedure. More details Read publication

Journal Article

Journal Article Spirituality, Staff support, Stillbirth 2015

The spiritual and theological issues raised by stillbirth for healthcare chaplains

Maternity healthcare chaplains are impacted by stillbirth as they provide spiritual care. Study shows that suffering, doubt and presence feature for chaplains in their pastoral care of families in stillbirth. More details Read publication

Journal Article

Journal Article Clinical guideline(s), Fetal growth restriction, Stillbirth 2015

Guidelines on fetal growth restriction: a comparison of recent national publications

Pregnancies affected by suboptimal fetal growth pose a daily challenge for obstetricians, however international guidelines are inconsistent and show variation, so consensus is urgently needed to inform best clinical practice. More details Read publication

Report

Report Stillbirth 2015

Invited commentary: The impact of stillbirth

Invited commentary by Professor O’Donoghue on the impact of stillbirth, published in the National Perinatal Epidemiology Centre’s Perinatal Mortality in Ireland Annual Report 2013. More details Read publication

Journal Article

Journal Article Multiple pregnancy 2014

Obstetric and perinatal outcomes of twin pregnancies conceived following IVF/ICSI treatment compared with spontaneously conceived twin pregnancies

There was no significant difference in obstetric or perinatal outcomes in a large series of dichorionic twins when spontaneous mode of conception was compared with assisted conception. More details Read publication

Journal Article

Journal Article 2014

Gestation-specific D-dimer reference ranges: a cross-sectional study

We found that there is a continuous increase in D-dimer concentrations across all gestations. This research is potentially beneficial to future diagnosis of venous thromboembolism in pregnancy using the new recommended 95th centile potential cut-offs. More details Read publication

Journal Article

Journal Article Multiple pregnancy 2014

Conjoined twins: Experience in an Irish tertiary centre

This case series describes a cluster of four sets of conjoined twins managed in one tertiary centre, with one set of survivors successfully separated after birth. More details Read publication

Journal Article

Journal Article Experience, Impact, Staff support, Staff training, Stillbirth 2014

The impact of stillbirth on consultant obstetrician gynaecologists: a qualitative study

Stillbirth is amongst the most challenging professional and personal experiences for consultant obstetricians. Study shows that stillbirth has personal impact and professional burden for clinicians. Recommendations are for improved training/ education and professional support. More details Read publication

Guideline

Guideline Clinical guideline(s), Stillbirth 2014

Clinical Practice Guideline: Fetal Growth Restriction - Recognition, Diagnosis & Management

Guideline produced for the Institute of Obstetricians and Gynaecologists and the Health Service Executive, 2014. More details Read publication

Journal Article

Journal Article 2014

Establishing trimester-specific maternal thyroid function reference intervals

This prospective study established trimester-specific thyroid function test reference intervals for pregnant women without thyroid disorders for use in clinical practice. More details Read publication

Journal Article

Journal Article Fetal growth restriction, Stillbirth 2014

Definition and management of fetal growth restriction: a survey of contemporary attitudes

A national survey of obstetricians showed inconsistencies around the clinical management of pregnancies complicated by fetal growth restriction, highlighting the need for standardisation of terminology and management in national guidance. More details Read publication

Journal Article

Journal Article Neonatal death, Stillbirth 2014

Fetal growth restriction and the risk of perinatal mortality–case studies from the multicentre PORTO study

Fetal growth restriction is a big contributor to perinatal mortality in normally-formed fetuses; antenatal detection of poor fetal growth and maternal risk factors can facilitate increased surveillance and timely delivery in many cases. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly 2013

The natural history of pregnancies with a diagnosis of Trisomy 18 or Trisomy 13; a retrospective case series

This large series of pregnancies with trisomy 13 and trisomy 18, in a setting where termination of pregnancy was unavailable, describes the natural history of these trisomies with useful information for pregnant women and healthcare professionals. More details Read publication

Journal Article

Journal Article Miscarriage, Pregnancy after loss, Termination of pregnancy 2013

Pregnancy loss managed by cervical dilatation and curettage increases the risk of spontaneous preterm birth

Pregnancy loss, either miscarriage or termination, managed by cervical dilatation and curettage increases the risk of spontaneous preterm birth in a subsequent pregnancy. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly 2013

Antenatal and intrapartum care of pregnancy complicated by lethal fetal anomaly

The antepartum and intrapartum care of pregnancies complicated by lethal fetal anomaly is unique and requires an individualised management plan to meet the significant obstetric, medical, bereavement care and psychosocial needs involved. More details Read publication

Journal Article

Journal Article Pregnancy loss 2013

Prevalence of subclinical and undiagnosed overt hypothyroidism in a pregnancy loss clinic

Subclinical and overt hypothyroidism may be a factor in unexplained pregnancy loss. More details Read publication

Journal Article

Journal Article 2012

Maternal serum cholesterol levels are elevated from the 1st trimester of pregnancy: A cross-sectional study

Use of pregnancy-specific reference ranges for cholesterol allows the early detection of maternal hypercholesterolaemia and may identify those at risk of cardiovascular disease. More details Read publication

Journal Article

Journal Article Perinatal pathology, Stillbirth 2012

Investigation of the role of computed tomography as an adjunct to autopsy in the evaluation of stillbirth

CT scanning has a role in the investigation of stillbirth and may be an option instead of post-mortem examination or as an adjunct, particularly for infants with congenital anomalies. More details Read publication

Book chapter

Book chapter Stillbirth 2012

Reduced fetal movements

Reduced fetal movements in pregnancy is common, causes concern and anxiety for pregnant women and healthcare professionals, and can be associated with poor pregnancy outcomes; therefore clinicians need guidance in standardised assessment of these pregnancies. More details Read publication

Journal Article

Journal Article 2012

Reference standard for serum bile acids in pregnancy

Serum bile acids do not change significantly during gestation in uncomplicated pregnancies and a single reference range can be used throughout pregnancy. More details Read publication

Journal Article

Journal Article Recurrent miscarriage 2011

Secondary recurrent miscarriage is associated with previous male birth

Previous reports suggest there may be a link between recurrent miscarriage and previous delivery of a viable male infant. This retrospective review did not demonstrate a significant association, but warrants further review with larger numbers of women. More details Read publication

Journal Article

Journal Article Fatal fetal anomaly, Termination of pregnancy for fetal anomalies 2010

The natural history of anencephaly

The natural history of anencephaly is described in a cohort of continuing pregnancies. More details Read publication

Journal Article

Journal Article Stillbirth 2009

Review: Reduced fetal movements

Reduced fetal movements in pregnancy is common, creates anxiety for both women and clinicians, and while it can be a sign of problems in the pregnancy or have no cause, it has an association with stillbirth. More details Read publication

Pregnancy Loss Research Group

Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, University College Cork, Fifth Floor, Cork University Maternity Hospital, Wilton, Cork, T12 YE02, Ireland,

Top