2013
Grants for Department
Thu, 14 Feb 2013
Dr. Dervla O'Malley and Professor Ken O'Halloran (Department of Physiology) were recently awarded a grant from Muscular Dystrophy Ireland for a collaborative project: Does crosstalk between corticotropin-releasing factor and interleukin-6 underlie skeletal and smooth muscle inflammation and dysfunction in the mdx mouse model of Duchenne Muscular Dystrophy?
Professor Edward Johns has received two major funding awards to support projects in the Renal Research Laboratory in the Department of Physiology. The first was and SFI Research Frontiers Programme grant which is to investigate the contribution of the angiotensin 1-7/ACE2 system in the regulation of renal haemodynamic and excretory function in models of hypertension. Knowledge of this system is sparse but the proposed research could open up avenues for translation into novel therapeutic development. The second award form the Wellcome Trust will investigate the contribution of brain angiotensin type 2 receptors (AT2R) in the reflex control of renal sympathetic nerve activity. There is evidence that activation of these receptors result in the generation of nitric oxide which may be a key mediator of AT2R activation and determine neuronal activity within the autonomic control centres of the brain
Dr F Markos is part of the MultiFun consortium which has been approved for funding. The research is focused on the development of functionalized nanoparticles for early stage detection and treatment of breast and pancreatic cancer, where cancer stem cells are the key target.