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EEG background activity, seizure burden and early childhood outcomes in neonatal encephalopathy in Uganda: a prospective feasibility cohort study

The Baby BRAiN study aimed to improve our understanding of newborn brain injury in Uganda and examined the impacts of events around the time of birth on both the baby’s brain and the child’s longer-term outcomes.

Authors

Mathieson SR, Nanyunja C, Sadoo S, Nakalembe S, Duckworth E, Muryasingura S, et al. 

Year
2024
Journal Name
The Lancet
Category
Journal Article
Link to Publication
https://doi.org/10.1016/j.eclinm.2024.102937

Abstract

Intrapartum-related neonatal encephalopathy (NE) is a leading cause of childhood mortality and morbidity. Continuous electroencephalography (EEG) is gold standard for neonatal brain monitoring; however, low-income country data is lacking. We examined EEG in a Ugandan cohort with NE to describe feasibility, background activity, seizure prevalence and burden, and associations with clinical presentation and outcome.

UCC Futures - Children

Todhchaíochtaí UCC - Páistí

  • Ursula Kilkelly, Professor, VP Global Engagement
  • Geraldine Boylan, Professor, Director INFANT Centre
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