Research Outputs
EEG background activity, seizure burden and early childhood outcomes in neonatal encephalopathy in Uganda: a prospective feasibility cohort study
The Baby BRAiN study aimed to improve our understanding of newborn brain injury in Uganda and examined the impacts of events around the time of birth on both the baby’s brain and the child’s longer-term outcomes.
- Authors
Mathieson SR, Nanyunja C, Sadoo S, Nakalembe S, Duckworth E, Muryasingura S, et al.
- Year
- 2024
- Journal Name
- The Lancet
- Category
- Journal Article
- Link to Publication
- https://doi.org/10.1016/j.eclinm.2024.102937
Abstract
Intrapartum-related neonatal encephalopathy (NE) is a leading cause of childhood mortality and morbidity. Continuous electroencephalography (EEG) is gold standard for neonatal brain monitoring; however, low-income country data is lacking. We examined EEG in a Ugandan cohort with NE to describe feasibility, background activity, seizure prevalence and burden, and associations with clinical presentation and outcome.