2024 Publications

1. Exposure to gestational diabetes mellitus increases subclinical inflammation mediated in part by obesity 

Andrea Musumeci, Colm John McElwain, Samprikta Manna, Fergus McCarthy, Cathal McCarthy, Exposure to gestational diabetes mellitus increases subclinical inflammation mediated in part by obesity, Clinical and Experimental Immunology, 2024

2. Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus

Colm J McElwain, Samprikta Manna, Andrea Musumeci, Isaac Sylvester, Chloé Rouchon, Anne Marie O'Callaghan, Mustafa Abdalla Bakhit Ebad, Fergus P McCarthy, Cathal M McCarthy, Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus, The Journal of Clinical Endocrinology & Metabolism, 2024

3. sFlt-1 impairs neurite growth and neuronal differentiation in SH-SY5Y cells and human neurons

Aaro Barron, Lauren Barrett, Jetro J. Tuulari, Linnea Karlsson, Hasse Karlsson, Cathal M. McCarthy, Gerard W. O'Keeffe; " sFlt-1 impairs neurite growth and neuronal differentiation in SH-SY5Y cells and human neurons". Bioscience Reports 1 May 2024

4. In Vivo Ocular Pharmacokinetics and Toxicity of Siponimod in Albino Rabbits

Rasha A. Alshaikh, Rania A. Salah El Din, Rania Gamal Eldin Zaki, Christian Waeber, and Katie B. Ryan. "In Vivo Ocular Pharmacokinetics and Toxicity of Siponimod in Albino Rabbits", Molecular Pharmaceutics , 2024

5. The future of pharmacology education: a global outlook

Guilding C, Kelly-Laubscher R, White P. The future of pharmacology education: a global outlook. Expert Rev Clin Pharmacol. 2024 Jan-Jun;17(2):115-118. 

6. Human α-synuclein overexpression upregulates SKOR1 in a rat model of simulated nigrostriatal ageing.

Morales-Prieto N, Bevans R, O'Mahony A, Barron A, Giles Doran C, McCarthy E, Concannon RM, Goulding SR, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. Human α-synuclein overexpression upregulates SKOR1 in a rat model of simulated nigrostriatal ageing. Aging Cell. 2024 Jun;23(6):e14155

7.Optogenetic induction of chronic glucocorticoid exposure in early-life leads to blunted stress-response in larval zebrafish.

Nagpal J, Eachus H, Lityagina O, Ryu S. Optogenetic induction of chronic glucocorticoid exposure in early-life leads to blunted stress-response in larval zebrafish. Eur J Neurosci. 2024 Jun;59(11):3134-3146.

8. A novel animal model for understanding secondary traumatic stress and visceral pain in male rats.

Lannon AS, Brocka M, Collins JM, Fitzgerald P, O'Mahony SM, Cryan JF, Moloney RD. A novel animal model for understanding secondary traumatic stress and visceral pain in male rats. Eur J Neurosci. 2024 May 2. doi: 10.1111/ejn.16353

9. An altered gut microbiome in pre-eclampsia: cause or consequence.

Deady C, McCarthy FP, Barron A, McCarthy CM, O'Keeffe GW, O'Mahony SM. An altered gut microbiome in pre-eclampsia: cause or consequence. Front Cell Infect Microbiol. 2024 May

10.Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation.

Ayagama T, Charles PD, Bose SJ, Boland B, Priestman DA, Aston D, Berridge G, Fischer R, Cribbs AP, Song Q, Mirams GR, Amponsah K, Heather L, Galione A, Herring N, Kramer H, Capel RA, Platt FM, Schotten U, Verheule S, Burton RAB. Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation. iScience. 2024 Mar 28;27(6)

11. Dementia research in Ireland: What should we prioritise?

Rogan C, Rock B, Begley E, Boland B, Brazil K, Diaz-Orueta U, Donnelly S, Foley M, Foley T, Hannigan C, Hopper L, Keogh F, Lawlor B, Leroi I, O'Neill C, O'Philbin L, Pertl M, Trépel D, Kennelly S. Dementia research in Ireland: What should we prioritise? HRB Open Res. 2023 Nov 2;6:12.

12. Extended siponimod release via low-porosity PLGA fibres: a comprehensive three-month in vitro evaluation for neovascular ocular diseases

Alshaikh RA, Chullipalliyalil K, Waeber C, Ryan KB. Extended siponimod release via low-porosity PLGA fibres: a comprehensive three-month in vitro evaluation for neovascular ocular diseases. Biomater Sci. 2024 Aug 19