Available UCC Technologies
Labocol - Cholosterol lowering probiotic yoghurt (Collaboration with Teagasc)
Teagasc and UCC researchers have developed an invention which allows a novel Lactic acid bacterial (LAB) strain, Lactobacillus mucosae, to be used in a nutritional approach to lowering cholesterol, e.g. in a probiotic yoghurt. Teagasc and UCC seek a commercial partner in the functional food space to further develop this technology with a view to commercialisation and further validation of the supporting health claims.
SUPER ‘NISIN’ BACTERIOCINS - Derivatives With Enhanced Antimicrobial Activity
Derivatives of Nisin are far superior to the current commercial Nisin A in antimicrobial activity. They are effective not only against a broader number of gram positive bacteria but some gram negative bacteria also. The derivatives have the added benefit of being effective at non-acidic pH, thereby allowing this ingredient to be applied in a greater range of food products.
Autophagy technology - Preventing cancer cell survival
A combination drug treatment comprising a chemotherapeutic drug and an autophagy inducing drug results in not only inhibition in the progression of cancer but also prevents the recurrence of cancer which may occur following withdrawal from a typical anti-cancer regime. A combination of 5-FU and LiCl treatment, for example, eliminates recovering cancer cells. The treatment overcomes drug resistance and results in chemoresistant cancer cells being killed by means of Type II cell death. The acceleration of autophagy beyond a survival process, into autophagic cell death is a new therapeutic approach to treating cancer.
ANSER -An Algorithm For Neonatal Seizure Recognition
Clinicians caring for neonates affected by seizures are poorly supported by specialist neurophysiology, especially out-of-hours, and there is an urgent unmet need for an intelligent cot-side seizure support tool. The ANSeR project team has developed a patented method for the real-time identification of seizures in an EEG signal that will automatically monitor the brain function of these babies and alert the clinician if there is a problem.
Smartpack - Antimicrobial Packaging Materials
PVC and LDPE Films with incorporated metal antimicrobial nanoparticles increase the shelf life of muscle foods compared to control films by retarding the microbiological growth of spoilage bacteria. During storage, the lipid oxidation values measured as TBARS values are also significantly lower than in control samples.
Mirstent - Cardiac repair therapy following heart attack
After suffering a heart attack (i.e. STEMI type), a single dose IGF-1 therapy is effective in decreasing the size of the dead heart tissue by at least 60%. Considering extensive use of stents in coronary angioplasty, eluting IGF1 from a stent is an ideal way to not only promote heart tis sue survival and repair, but also to prevent early stent restenosis (blockage) or delayed thrombosis ( blood clots), being the common side-effects associated with stenting. IGF1 delivered on a stent will thus add substantially to the current structural benefits of stent implantation in the STEMI setting. Moreover tissue repair will reduce the requirement for defibrillator implantation in a large number of patients whose heart function continues to deteriorate over the first two months following an attack. This stent will therefore provide a major cost saving for healthcare providers as well as health benefit in patients suffering heart attacks
RADFETS - Low cost, minature size radiation detectors
RADFET is a MOS transistor optimised for radiation sensitivity. RADFET chip is a cube with a side of 0.5mm. Ionising radiation induces charge in the RADFET , which changes one of the basic transistor’s parameters – threshold voltage. Threshold voltage can easily be measured by passing a specified current through the RADFET and measuring a DC voltage at the device output. That DC voltage is indicative of the absorbed radiation dose.
sLEDS - Surface emitting UV-blue light source
This is a surface emitting UV - blue light source f or applications that require a high illumination density . It is d esigned for easy integration with additional filters, etc
PwrSoC - Micro-Fabricated Inductors for Power-supply-in-package
Mobility, form - factor and battery life are key in consumer electronic design today. Battery life requirements have motivated a move from inefficient linear regulators to more efficient switching regulators. However, the disadvantage of the switching regulator is that it is generally a multiple component solution, requiring external, discrete components placed alongside an active semiconductor device. This disadvantage can be reduced if these passive components can be miniaturised and integrated into the package, or on - chip, so as to achieve a single chip switching converter or “Power supply on Chip” (PwrSoC). The most important and challenging device to integrate is the inductor, since it is often physically large, and not usually compatible with semiconductor device package technology. This technical challenge has been addressed by the new Tyndall integrated micro - inductor technology.
Low loss magentic power - Ultra-low loss thin film magnetics for future power supplies
A fundamental roadblock in advancing the magnetic passive device technology for high frequencies is the availability of suitable magnetic material. Presently, ferrites are used as magnetic core material in these applications. Ferrite material has low loss performance at frequencies of 130 kHz and 100 mT of peak applied field, with a loss density of 300 kW/m3, additionally, low flux density of ferrites ha s restricted the magnetic components to larger footprint/volume. Tyndall National Institute have developed novel soft magnetic alloy compositions and rapid quenching processing technology for low - loss nano-crystalline films to address t he challenge to develop high flux density, low loss and lower footprint magnetic components working up to frequencies of 5 - 10 MHz.