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TRAP Funding
Translational Research Access Programme
IMPORTANT NOTICE TO POTENTIAL TRAP APPLICANTS 2019
TRAP applicants should appraise themselves of the application timeframes and associated approval timeframes for those projects that require CREC approval https://www.ucc.ie/en/crec/.
APPLICATIONS PROCESS IS NOW CLOSED.
TRAP 2019 will be the ninth-year that funding has been made available through the School of Medicine. TRAP provides start-up funding for researchers in UCC and its affiliated clinical institutions. TRAP provides access to state-of the-art research facilities & equipment, with the explicit intention of promoting collaborative translational research within the UCC healthcare community.
The purpose of TRAP is to develop meaningful partnerships with UCC colleagues in clinical, pre-clinical and other disciplines relevant to their research areas. It is intended to provide an opportunity for pairs of researchers (one clinician and one non-clinician investigator) to mutually develop new areas of research and to foster them to a point where a more substantial grant application can be made.
Please note that funding will not be awarded to successful applicants until a copy of the ethical approval letter for the project has been submitted to the Medical School.
What can be achieved with the School of Medicine TRAP seed funding?
What can be achieved with the School of Medicine TRAP seed funding? by Drs Suzanne Timmons and Des Murphy.
Publications
Prostaglandin E2 & the EP receptors in malignancy:possible therapeutic targets?
- R. O’Brien, M.M. Buckley, K.D. O’Halloran, D. O’Malley. A GLP-1 mimetic alleviates Irritable Bowel Syndrome-like symptoms in the Wistar Kyoto rat. EB 2016, April 2016, San Diego, US. (poster presentation).
- R. O’Brien and D.O’Malley. Irish Epithelial Physiology Group. Neurocrine effects of GI hormones. October 2015, Kilkenny, Ireland. Invited speakers.
- R. O’Brien, M.M. Buckley, D. O’Malley. GLP-1 evokes calcium responses in submucosal neurons, via activation of the JAK/STAT and PI 3-kinase pathways in Sprague Dawley colonic tissue. RAMI, Dublin, June 2015. (poster presentation – POSTER PRIZE)
- R. O’Brien, M.M. Buckley and D O’Malley. IBS plasma sensitises colonic submucosal neurons to GLP-1-evoked activation. ESNM, Istanbul, June 2015. (poster presentation)
- Kelliher A, O’Sullivan L, Buckley M and O’Malley D. Crosstalk between GLP-1 and IL-6 in isolated rat myenteric and submucosal neurons. RAMI UCC, June 2013. Poster.
- DO’Malley. Invited speaker (Rising Stars) to ‘On the constancy of the internal environment – a celebration of Claude Bernard’ hosted by UCC, June 2013. Glucagon-like peptide 1: A potential role in functional bowel disorders.
TRAP recipients 2019
TRAP recipient | TRAP recipient | TRAP receipient | Title |
---|---|---|---|
Dr Barry Boland | Prof William Molloy | Investigating the relationship between labile zinc (ZN2+) and zinc amino acid complexes in Alzheimer's disease | |
Dr Eric Kelleher | Prof John Cryan | Clinical Characteristics, inflammatory markers and microbiota in patients with Functional Neurological disorders receiving a physiotherapy intervention | |
Dr Aine Merwick | Dr Christian Waeber | Suppressive lymphocyte profiles in patients post stroke/TIA (SLIPS) | |
Dr Grainne Murphy | Dr Michael T Henry | Dr John MacSharry | Alternations in the lung microbiome in idiopathic pulmonary fibrosis (IPF) pre and post treatment with perfenidone |
Dr Elizabeth Brint | Dr Marcus Kennedy | To determine the biological consequences of IL-36 signalling in lung cancer |
TRAP Awardees 2018
Trap Awardees 2018 |
||
Dr Gerard Clarke
|
Professor Jonathan Hourihane
|
Examining changes to infant gut microbiota during oral tolerance induction for cow’s milk allergy. |
Dr Aileen Houston
|
Professor Michael O’Riordain
|
Death Receptor family members as targets for cancer therapy.
|
Dr Fiona McDonald
|
Professor Eugene Dempsey Professor Ken O’Halloran
|
A trilogy of stressors in the NICU: Towards a therapy for preterm adversity.
|
Professor Joe Eustace
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Dr Julie O’Neill Dr Mohammed Abdulla |
Gut Dysbiosis and CKD: Cause or Consequence?
|
Consultant George Finbarr Kaar
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Dr Yvonne Nolan
|
Diagnosis and monitoring of therapeutic response in glioma patients through sequencing of cerebrospinal fluid-derived circulating tumour DNA, micro RNA, and characterisation of plasma-derived extracellular vesicles. |
TRAP Awardees 2017
Trap Awardees 2017
|
||
Dr Collette Hand
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Dr Cynthia Heffron
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Characterisation of gene mutations in Irish melanoma patients. |
Professor Mary Cahill
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Dr Paul Young Dr Gerardine Meade-Murphy |
Hyperactive platelets in Myeloma: a druggable target in the prevention of myeloma-associated thrombosis. |
Dr Liam Fanning |
Dr Desmond Murphy |
Capturing The Allergens of Asthma. |
Professor Henry Paul Redmond
|
Dr André Toulouse
|
Characterisation of tissue and blood biomarkers of response and progression in a murine model of melanoma brain metastasis following treatment with a combination of Nivolumab and Ipilimumab. |
Dr Siobhain O’Mahony
|
Professor George Shorten
|
Patient response to lumbar epidural steroid injection for recent onset unilateral radicular low back pain: potential association with gut microbiota diversity and composition.
|
TRAP Awardees 2016
TRAP Awardees 2016 | ||
Dr Elizabeth Brint | Dr Louise Burke | To examine whether expression of IL-36 cytokines are potential biomarkers for progression of lung cancer |
Dr Conor Deasy | Dr Simon Woodworth | Can wearable technology be used to continuously measure the vital signs of patients presenting to an emergency department? A pilot study |
Dr Sheena McHugh | Dr Kieran O'Connor | Examining the implementation of a falls prevention programme in community hospitals and the factors influencing its success |
Dr Conleth Murphy | Dr Kellie Dean | Long, non--‐coding RNA BC200 in ductal carcinoma in situ (DCIS) of the breast: defining a novel biomarker to facilitate early diagnosis |
TRAP Awardees 2015
TRAP Awardees 2015 | ||
Dr John McSharry | Dr Desmond Murphy | Exploring the role of the Microbiome in Asthma |
Dr Justin McCarthy | Dr Michael Bennett | Defining the Expression of tumour-‐associated antigen EpCAM Signalling molecules in primary and metastatic human breast cancers: implications for the definition of novel prognostic subtypes and cancer therapy |
Dr Andre Toulouse | Dr Niamh Bermingham | Retinoic acid receptor expression in gliomas |
Dr Gerard Clarke | Dr Louise Kenny | Stress-induced Enhanced Gastrointestinal Permeability During Pregnancy: Impact on Maternal Immunology and Tryptophan Metabolism |
Dr Dervla O Malley | Dr Juliette Buckley | Does ghrelin sensitise colonic myenteric neurons to the stimulatory effects of Glucagon-like peptide-1? |
Dr Frederid Vernimmen | Dr M Morris & Dr JD Holmes | Radiation dose enhancement of endothelial cells by cell membrane located gold nanoparticles |
TRAP Awardees 2014
TRAP Awardees 2014 | ||
Dr Elizabeth Brint | Dr Michael Bennett | The IL -33/ST2 axis and its potential involvement in human turmorigenesis |
Dr Aileen Houston | Dr Paul Redmond | FasL and EP1 recepton.: Novel therapeutic strategies in metastatic colon cancer |
Dr Grace O Callaghan | Dr Niall Hyland & Dr Barry O' Reilly | Identification of novel biomarkers and pathophysiological features of bladder pain syndrome |
Dr Thomas Murphy | Dr Paul O Toole | The oesophagitis to adenocarcinoma sequence: The role of the microbiome |
Dr Gerard O' Keefe | Dr Louise Kenny | To determine the effects and mechanisms by which prenatal stress reduces placntal HSD1182 expression and to develop protective pharmacotherapy for the human placenta |
Dr Harriett Schellekens | Dr Derek Power | Neuoendocrine and Gut Microbiome Biomarkers in Pancreatic Cancer Cachexia |
TRAP Awardees 2013
TRAP Awardees 2013 | ||
Dr Barry Boland | Prof. William Molloy | Novel profiling of multiple amyloid precourssor protein (App) metabolites in cerebrospinal fluid – potential biomarkers for Alzheimer’s disease. |
Dr Gerard Clarke | Dr Aoife Ni Chororain | Too Stressed to Care: Attending to the Biological Burden of a Social Responsibility |
Dr Eugene Dempsey | Dr Paul Galvin | Facilitating Neonatal Intubation with Chip on Tip Technology |
Dr Eric J Downer | Dr Orna O Toole | Interferon-β as a cannabinoid target in Multiple Sclerosis therapy |
Dr Peter Filan | Dr Ciara Greene | Brain development in Trisomy 21 at birth: a neonatal magnetic resonance imaging and post-acquisition image processing development study. |
Dr Mark Corrigan | Dr Bridget Maher | MEMO - technological Mobility Enabling patient Mobility Outcomes |
Dr Andre Toulouse | Dr Brendan Fitzgerald | Investigation of Morphological and Functional Aspects of Syncytiotrophoblast Nuclear Organization Patterns in the Human Placenta |
TRAP Awardees 2012
TRAP Awardees 2012 | ||
Dr Liam Fanning | Dr Deirdre Murray | Exploring the neonatal virome: A potential window into diseases of unknown or uncharacterised aetiology. |
Dr Collette Hand | Dr Aishling Ryan | A Phenotypic & Genotypic Study of Periodic Paralysis in an Irish Population |
Dr Janas Harrington | Dr Joe Eustace | Quantification of Dietary Macro/Micronutrient Content using Digital Imaging |
Professor Tommie McCarthy | Dr Ted Dinan | Genome Analysis of a Family with a Strong Familial Depression |
Dr Tom Moore | Dr James Clover | Use of Human Pregnancy-specific Glycoprotein 1 (PSG1) to promote Wound Healing. |
Dr Dervla O'Malley | Dr Eamonn Quigley | Studies to investigate crosstalk between Interleukin-6 and Glucagon-Like Peptide-1 and their influence of the pathophysiology of Irritable Bowel Syndrome |
Dr Colm O'Tuathaigh | Dr Ted Dinan | Translational genetic study of microRNAs (miRNA’s) in schizophrenia |
Dr Mark Tangney | Dr Deirdre O'Hanlon | Identification of bacterial species naturally present in patient tumours |
Dr Suzanne Timmons | Dr Cora O'Neill | Peripheral Akt activity in Parkinsons Disease – a potential biomarker of disease status and response to neuroprotective treatments |
Dr Aideen Sullivan | Dr Sean O'Sullivan | Potential biomarkers for Parkinsons disease: comparison of levels of neurotrophic factors in cerebrospinal fluid and serum of Parkinsons disease patients with those in healthy controls |