TRAP Funding

Translational Research Access Programme

IMPORTANT NOTICE TO POTENTIAL TRAP APPLICANTS 2019

TRAP applicants should appraise themselves of the application timeframes and associated approval timeframes for those projects that require CREC approval https://www.ucc.ie/en/crec/.

APPLICATIONS PROCESS IS NOW CLOSED.

TRAP 2019 will be the ninth-year that funding has been made available through the School of Medicine. TRAP provides start-up funding for researchers in UCC and its affiliated clinical institutions. TRAP provides access to state-­of the-­art research facilities & equipment, with the explicit intention of promoting collaborative translational research within the UCC healthcare community.

The purpose of TRAP is to develop meaningful partnerships with UCC colleagues in clinical, pre-­clinical and other disciplines relevant to their research areas. It is intended to provide an opportunity for pairs of researchers (one clinician and one non-­clinician investigator) to mutually develop new areas of research and to foster them to a point where a more substantial grant application can be made.

Please note that funding will not be awarded to successful applicants until a copy of the ethical approval letter for the project has been submitted to the Medical School.

 

 

What can be achieved with the School of Medicine TRAP seed funding?

  What can be achieved with the School of Medicine TRAP seed funding? by Drs Suzanne Timmons and Des Murphy.

 

 

Publications

Prostaglandin E2 & the EP receptors in malignancy:possible therapeutic targets?

Abstracts: Dr Dervla O' Malley:
  1. R. O’Brien, M.M. Buckley, K.D. O’Halloran, D. O’Malley.  A GLP-1 mimetic alleviates Irritable Bowel Syndrome-like symptoms in the Wistar Kyoto rat. EB 2016, April 2016, San Diego, US. (poster presentation).
  2. R. O’Brien and D.O’Malley. Irish Epithelial Physiology Group. Neurocrine effects of GI hormones. October 2015, Kilkenny, Ireland. Invited speakers.
  3. R. O’Brien, M.M. Buckley, D. O’Malley. GLP-1 evokes calcium responses in submucosal neurons, via activation of the JAK/STAT and PI 3-kinase pathways in Sprague Dawley colonic tissue. RAMI, Dublin, June 2015. (poster presentation – POSTER PRIZE)
  4. R. O’Brien, M.M. Buckley and D O’Malley. IBS plasma sensitises colonic submucosal neurons to GLP-1-evoked activation. ESNM, Istanbul, June 2015. (poster presentation)
  5. Kelliher A, O’Sullivan L, Buckley M and O’Malley D. Crosstalk between GLP-1 and IL-6 in isolated rat myenteric and submucosal neurons. RAMI UCC, June 2013. Poster.
  6. DO’Malley. Invited speaker (Rising Stars) to ‘On the constancy of the internal environment – a celebration of Claude Bernard’ hosted by UCC, June 2013. Glucagon-like peptide 1: A potential role in functional bowel disorders.

 

TRAP recipients 2019

TRAP recipient TRAP recipientTRAP receipientTitle
Dr Barry Boland Prof William Molloy   Investigating the relationship between labile zinc (ZN2+) and zinc amino acid complexes in Alzheimer's disease
Dr Eric Kelleher Prof John Cryan   Clinical Characteristics, inflammatory markers and microbiota in patients with Functional Neurological disorders receiving a physiotherapy intervention
Dr Aine Merwick Dr Christian Waeber   Suppressive lymphocyte profiles in patients post stroke/TIA (SLIPS)
Dr Grainne Murphy Dr Michael T Henry Dr John MacSharry Alternations in the lung microbiome in idiopathic pulmonary fibrosis (IPF) pre and post treatment with perfenidone
Dr Elizabeth Brint Dr Marcus Kennedy   To determine the biological consequences of IL-36 signalling in lung cancer

TRAP Awardees 2018

Trap Awardees 2018

Dr Gerard Clarke

 

Professor Jonathan Hourihane

 

Examining changes to infant gut microbiota during oral tolerance induction for cow’s milk allergy.

Dr Aileen Houston

 

Professor Michael O’Riordain

 

Death Receptor family members as targets for cancer therapy.

 

Dr Fiona McDonald

 

 

Professor Eugene Dempsey

Professor Ken O’Halloran

 

A trilogy of stressors in the NICU: Towards a therapy for preterm adversity.

 

Professor Joe Eustace

 

Dr Julie O’Neill

Dr Mohammed Abdulla

Gut Dysbiosis and CKD: Cause or Consequence?

 

Consultant George Finbarr Kaar

 

 

 

Dr Yvonne Nolan

 

 

 

Diagnosis and monitoring of therapeutic response in glioma patients through sequencing of cerebrospinal fluid-derived circulating tumour DNA, micro RNA, and characterisation of plasma-derived extracellular vesicles.

TRAP Awardees 2017

Trap Awardees 2017

 

Dr Collette Hand

 

Dr Cynthia Heffron

 

Characterisation of gene mutations in Irish melanoma patients.

Professor Mary Cahill

 

Dr Paul Young

Dr Gerardine Meade-Murphy

Hyperactive platelets in Myeloma: a druggable target in the prevention of myeloma-associated thrombosis.

Dr Liam Fanning

Dr Desmond Murphy

Capturing The Allergens of Asthma.

Professor Henry Paul Redmond

 

 

 

Dr André Toulouse

 

 

 

Characterisation of tissue and blood biomarkers of response and progression in a murine model of melanoma brain metastasis following treatment with a combination of Nivolumab and Ipilimumab.

Dr Siobhain O’Mahony

 

 

 

Professor George Shorten

 

 

 

Patient response to lumbar epidural steroid injection for recent onset unilateral radicular low back pain: potential association with gut microbiota diversity and composition.

 

TRAP Awardees 2016

TRAP Awardees 2016
Dr Elizabeth Brint Dr Louise Burke To examine whether expression of IL-36 cytokines are potential biomarkers for progression of lung cancer
Dr Conor Deasy Dr Simon Woodworth Can wearable technology be used to continuously measure the vital signs of patients presenting to an emergency department? A pilot study
Dr Sheena McHugh Dr Kieran O'Connor Examining the implementation of a falls prevention programme in community hospitals and the factors influencing its success
Dr Conleth Murphy Dr Kellie Dean Long, non--‐coding RNA BC200 in ductal carcinoma in situ (DCIS) of the breast: defining a novel biomarker to facilitate early diagnosis

TRAP Awardees 2015

TRAP Awardees 2015
Dr John McSharry Dr Desmond Murphy Exploring the role of the Microbiome in Asthma
Dr Justin McCarthy Dr Michael Bennett Defining the Expression of tumour-­‐associated antigen EpCAM Signalling molecules in primary and metastatic human breast cancers: implications for the definition of novel prognostic subtypes and cancer therapy
Dr Andre Toulouse Dr Niamh Bermingham Retinoic acid receptor expression in gliomas
Dr Gerard Clarke Dr Louise Kenny Stress-induced Enhanced Gastrointestinal Permeability During Pregnancy: Impact on Maternal Immunology and Tryptophan Metabolism
Dr Dervla O Malley Dr Juliette Buckley Does ghrelin sensitise colonic myenteric neurons to the stimulatory effects of Glucagon-like peptide-1?
Dr Frederid Vernimmen Dr M Morris & Dr JD Holmes Radiation dose enhancement of endothelial cells by cell membrane located gold nanoparticles

TRAP Awardees 2014

TRAP Awardees 2014
Dr Elizabeth Brint Dr Michael Bennett The IL -33/ST2 axis and its potential involvement in human turmorigenesis
Dr Aileen Houston Dr Paul Redmond  FasL and EP1 recepton.: Novel therapeutic strategies in metastatic colon cancer
Dr Grace O Callaghan Dr Niall Hyland & Dr Barry O' Reilly Identification of novel biomarkers and pathophysiological features of bladder pain syndrome
Dr Thomas Murphy Dr Paul O Toole The oesophagitis to adenocarcinoma sequence: The role of the microbiome
Dr Gerard O' Keefe Dr Louise Kenny To determine the effects and mechanisms by which prenatal stress reduces placntal HSD1182 expression and to develop protective pharmacotherapy for the human placenta
Dr Harriett Schellekens Dr Derek Power Neuoendocrine and Gut Microbiome Biomarkers in Pancreatic Cancer Cachexia

TRAP Awardees 2013

TRAP Awardees 2013
Dr Barry Boland Prof. William Molloy Novel profiling of multiple amyloid precourssor protein (App) metabolites in cerebrospinal fluid – potential biomarkers for Alzheimer’s disease.
Dr Gerard Clarke Dr Aoife Ni Chororain Too Stressed to Care: Attending to the Biological Burden of a Social Responsibility
Dr Eugene Dempsey Dr Paul Galvin Facilitating Neonatal Intubation with Chip on Tip Technology
Dr Eric J Downer Dr Orna O Toole Interferon-β as a cannabinoid target in Multiple Sclerosis therapy
Dr Peter Filan Dr Ciara Greene Brain development in Trisomy 21 at birth: a neonatal magnetic resonance imaging and post-acquisition image processing development study.
Dr Mark Corrigan Dr Bridget Maher MEMO - technological Mobility Enabling patient Mobility Outcomes
Dr Andre Toulouse Dr Brendan Fitzgerald Investigation of Morphological and Functional Aspects of Syncytiotrophoblast Nuclear Organization Patterns in the Human Placenta

TRAP Awardees 2012

TRAP Awardees 2012
Dr Liam Fanning  Dr Deirdre Murray Exploring the neonatal virome: A potential window into diseases of unknown or uncharacterised aetiology.
Dr Collette Hand Dr Aishling Ryan A Phenotypic & Genotypic Study of Periodic Paralysis in an Irish Population
Dr Janas Harrington Dr Joe Eustace Quantification of Dietary Macro/Micronutrient Content using Digital Imaging
Professor Tommie McCarthy Dr Ted Dinan Genome Analysis of a Family with a Strong Familial Depression
Dr Tom Moore Dr James Clover Use of Human Pregnancy-specific Glycoprotein 1 (PSG1) to promote Wound Healing.
Dr Dervla O'Malley Dr Eamonn Quigley Studies to investigate crosstalk between Interleukin-6 and Glucagon-Like Peptide-1 and their influence of the pathophysiology of Irritable Bowel Syndrome
Dr Colm O'Tuathaigh Dr Ted Dinan Translational genetic study of microRNAs (miRNA’s) in schizophrenia
Dr Mark Tangney Dr Deirdre O'Hanlon Identification of bacterial species naturally present in patient tumours 
Dr Suzanne Timmons  Dr Cora O'Neill Peripheral Akt activity in  Parkinsons Disease – a potential biomarker of disease status and response to neuroprotective treatments 
Dr Aideen Sullivan Dr Sean O'Sullivan Potential biomarkers for Parkinsons disease: comparison of levels of neurotrophic factors in cerebrospinal fluid and serum of Parkinsons disease patients with those in healthy controls                           

School of Medicine

Scoil an Leighis

Room 2.59, T12 AK54

Top