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Lorena Morales García

Research Interests

Role of Maternal Gut-Microbiota in the neurovascular development of the hypothalamus

Her project objectives are:

To evaluate the development, structure, and function of neurovascular interactions after gut microbiome disruption in prenatal life using germ-free (GF; lack of all microorganisms) mice and one translationally relevant disruptor: antibiotics administration (ABX).

To analyze the radial glial (RG) neural progenitor lineages of the alar hypothalamus and its RG-derived cell populations in GF and ABX mouse models.

To evaluate the microbiome-derived metabolites and the molecular mechanisms involved in microbiota- hypothalamic neurovascular communication.

Her project work aims to tackle the Global societal challenge of Non-communicative diseases (NCDs) or neurodevelopmental disorders.

INSPIRE

APC Microbiome Ireland, Biosciences Building, University College Cork, Ireland,

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