Aoife Corcoran
Biography
BSc Genetics, University College Cork
PhD Supervisor: Prof. Tom Cotter
The NADPH oxidase (Nox) family of enzymes generate reactive oxygen species (ROS) which have been shown to be involved in the regulation of various intracellular signalling pathways. Due to their different locations, both within cells and within tissues, this group of proteins affect many cellular functions including growth, motility and cell survival. My research is centered on the role of Nox-driven cell survival signalling in acute myeloid leukemia (AML).