Participating Investigators and Research Areas

Principal Investigators
Professor John F. Atkins
School of Biochemistry and Cell Biology
Research Area: Regulation of growth regulatory genes by ribosomal frame shifting in translation
Dr. Pavel Baranov
School of Biochemistry and Cell Biology
Research Area: Identification of abnormalities in post-transcriptional regulation of gene expression in cancer cells
Dr. Orla P. Barry
Department of Pharmacology and Therapeutics
Research Area: Protein kinases and the regulation of apoptotic responses in oesophageal, renal and prostate carcinogenesis
Professor Noel Caplice
Department of Medicine
Research Area: Characterizing and targeting vascular stem cells in angiogenesis
Professor Thomas G. Cotter
School of Biochemistry and Cell Biology
Research Area: The role of Nox driven hydrogen peroxide generation in promoting tumour cell survival
Dr. John (Eoin) F. Fleming
School of Biochemistry and Cell Biology and School of Pharmacy
Research Area: Histidine decarboxylase function in H. Pylori infection and gastric cancer
Dr. Aileen Houston
Department of Medicine
Research Area: Fas signalling and carcinogenesis
Professor Louise Kenny
Department of Obstetrics and Gynaecology
Research Area: Trophoblast model of cell invasion for analysis of signalling
Professor Mary McCaffrey
School of Biochemistry and Cell Biology
Research Area: Role of Rab25 GTPase and myosin Vb in the aggressiveness of cancer
Dr. Justin V. McCarthy
School of Biochemistry and Cell Biology
Research Area: Presenlin-mediated regulation of survival signalling
Professor Tommie McCarthy
School of Biochemistry and Cell Biology
Research Area: Investigation of RYR in Ca2+ signalling and Ca2+homeostasis in B-lymphocytes
Dr. Sharon McKenna
Cork Cancer Research Centre
Research Area: Role of Bcr-Abl modulated genes in drug resistance and survival
Dr. Tom Moore
School of Biochemistry and Cell Biology
Research Area: Anti-inflammatory and pro-angiogenic functions of the pregnancy-specific glycoproteins
Professor Rosemary O'Connor
School of Biochemistry and Cell Biology
Research Area: Insulin-like Growth Factor system in cancer and normal cells: signalling pathways and their regulation and new target genes (Pnc1, Hrg-1, Mystique/PDLIM2)
Professor Catriona O'Driscoll
School of Pharmacy
Research Area: Novel methods of drug delivery in cancer
Dr. Cora O'Neill
School of Biochemistry and Cell Biology
Research Area: PTEN phosphatase - common function in cancer and neurodegeneration
Professor Dmitri B. Papkovsky
School of Biochemistry and Cell Biology
Research Area: Cell metabolism and mitochondrial function in cancer development and treatment
Professor H. Paul Redmond
Department of Surgery
Research Area: Signalling in post-operative tumour growth
Dr. Mark Tangney
Cork Cancer Research Centre
Research Area: Gene therapy and tumour imaging
Dr. Paul Young
School of Biochemistry and Cell Biology
Research Area: The role of the actinin family of actin-binding proteins in cell adhesion and motility