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Postgraduate Seminars
Postgraduate Seminars

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2020 Postgraduate Seminars
Molecular genetics of major depressive disorder in a large Irish pedigree
PhD Candidate: Roisin Bogue
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
A novel biomolecular nanomachine as a non-toxic, non-viral system for efficient delivery of functionally active genome editing components (CRISPR-cas9 and nucleotides)
PhD Candidate: Emer Cantillon
Supervisor: Dr Eoin Fleming, School of Biochemistry and Cell Biology
Exploring difficult regions in the human genome: non-coding RNAs arising from the PSG multi-copy coding gene locus
PhD Candidate: Maria De los Angeles Becerra Rodriguez
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
Development of a sensor-based rapid microbial testing platform for the Irish meat industry
PhD Candidate: Sophia Elisseva
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology & Dr Joseph Kerry, School of Food and Nutritional Sciences
Identification of non-AUG-initiated proteoforms in mammals
PhD Candidate: Alla Fedorova
Supervisor: Professor Pavel Baranov, School of Biochemistry and Cell Biology
Regulation of IGF-1R intracellular trafficking and its contribution to organelle activity
PhD Candidate: Grant Godsmark
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Identification of biomarkers for the diagnosis, management and follow-up of women with gestational trophoblastic disease
PhD Candidate: Caroline Joyce
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology & Professor Keelin O'Donoghue, Department of Obstetrics and Gynaecology
Investigating the host-microbe dialogue in aging
PhD Candidate: Christina Killian
Supervisor: Dr Susan Joyce, School of Biochemistry and Cell Biology & Dr David Clarke, School of Microbiology
The IGF-1 signalling pathway in mitochondrial protection
PhD Candidate: Joss Murray
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Regulation and function of Ube2j1
PhD Candidate: Algoofi Noor
Supervisor: Dr Eoin Fleming, School of Biochemistry and Cell Biology
Defining gut mediated metabolism for health and disease
PhD Candidate: Karina Quilter
Supervisor: Dr Susan Joyce, School of Biochemistry and Cell Biology & Dr Silvia Melgar, Alimentary Pharmabotic Centre
Development of online approaches for kinaesthetic learning in science
PhD Candidate: Anna Scanlan
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology & Dr Declan Kennedy, School of Education, UCC
Design of new photonic imaging systems for biomedical applications
PhD Candidate: Rajannya Sen
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology & Professor Stefan Andersson-Engels, Tyndall National Institute
The roles of early gut colonizers, E. coli and Bacteroides, in bile acid metabolism and gut homeostasis in the infant gut
PhD Candidate: Katie Wall
Supervisor: Dr Susan Joyce, School of Biochemistry and Cell Biology & Dr David Clarke, School of Microbiology
A family of multi-functional phosphorescent bioprobes based on the PtTFPP scaffolding moiety
PhD Candidate: Chiara Zanetti
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology & Professor Anita Maguire, School of Chemistry
2019 Postgraduate Seminars
Molecular genetics of major depressive disorder in a large Irish pedigree
PhD Candidate: Roisin Bogue
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
Sensor-based rapid microbial testing technology for the Irish meat industry
PhD Candidate: Sophia Elisseva
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Translational landscape of Kluyveromyces marxianus revealed with ribosome profiling
PhD Candidate: Darren Fenton
Supervisor: Professor Pavel Baranov, School of Biochemistry and Cell Biology & Dr John Morrissey, School of Microbiology
IGF-1 mediated regulation of IGF-1 Receptor internalization and its contribution to mitochondrial activity
PhD Candidate: Grant Godsmark
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Receptor interplay in longevity and aging: investigating the host-microbe dialogue
PhD Candidate: Christina Killian
Supervisor: Dr Susan Joyce, School of Biochemistry and Cell Biology & Dr David Clarke, School of Microbiology
Utilising ribosome profiling data to discover novel regions of translation in human
PhD Candidate: Stephen Kiniry
Supervisor: Professor Pavel Baranov, School of Biochemistry and Cell Biology
IGF-1 promotion of mitochondrial protection in cancer
PhD Candidate: Joss Murray
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Regulation and function of Ube2j1
PhD Candidate: Algoofi Noor
Supervisor: Dr Eoin Fleming, School of Biochemistry and Cell Biology
Investigation of platelet function in Multiple Myeloma and the role of α-Actinin-1 in platelet function and disease
PhD Candidate: Leanne O'Sullivan
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Investigation of the TNF superfamily of ligands as potential therapeutic targets in Inflammatory Bowel Disease (IBS)
PhD Candidate: Subhasree Rajaram
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology
Identification of adhesion-related mechanisms and proteins facilitating IGF-1R function and activity in cancer
PhD Candidate: Leonie Reiger
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
IGF-1 mediates mitochondrial protection through regulation of mitochondrial turnover
PhD Candidate: Sarah Riis
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Investigating the association between long non-coding RNAs and ductal carcinoma in situ (DCIS)
PhD Candidate: Julia Samson
Supervisor: Dr Kellie Dean, School of Biochemistry and Cell Biology
Development of online approaches for kinaesthetic learning in science
PhD Candidate: Anna Scanlan
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology & Dr Declan Kennedy, School of Education, UCC
Design of new photonic imaging systems for biomedical applications
PhD Candidate: Rajannya Sen
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
2018 Postgraduate Seminars
Structural basis of translational recoding
PhD Candidate: Pramod Bhatt
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
Translational landscape of Kluyveromyces marxianus revealed with ribosome profiling
PhD Candidate: Darren Fenton
Supervisor: Professor Pavel Baranov, School of Biochemistry and Cell Biology & Dr John Morrissey, School of Microbiology
Investigation of mechanisms by which PINK1 protects against Parkinson’s disease: development of biomarkers and treatment targets
PhD Candidate: Rachel Furlong
Supervisor: Professor Cora O’Neill, School of Biochemistry and Cell Biology & Professor Aideen Sullivan, Department of Anatomy and Neuroscience
Receptor interplay in longevity and aging: investigating the host-microbe dialogue
PhD Candidate: Christina Killian
Supervisor: Dr Susan Joyce, School of Biochemistry and Cell Biology & Dr David Clarke, School of Microbiology
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PhD Candidate: Stephen Kiniry
Supervisor: Professor Pavel Baranov, School of Biochemistry and Cell Biology
Investigation of platelet function in Multiple Myeloma and the role of α-Actinin-1 in platelet function and disease
PhD Candidate: Leanne O'Sullivan
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Investigation of the TNF superfamily of ligands as potential therapeutic targets in Inflammatory Bowel Disease (IBS)
PhD Candidate: Subhasree Rajaram
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology
The role of C-terminal phosphotyrosine Y-1250/Y-1251 for IGF-1 Receptor internalization and degradation
PhD Candidate: Leonie Reiger
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
The effects of Insulin-like Growth Factor-1 signalling on mitochondrial homeostasis in cancer
PhD Candidate: Sarah Riis
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Investigating the association between long non-coding RNAs and ductal carcinoma in situ (DCIS)
PhD Candidate: Julia Samson
Supervisor: Dr Kellie Dean, School of Biochemistry and Cell Biology
2017 Postgraduate Seminars
Investigation of the underlying mechanism of stop codon UGA redefinition
PhD Candidate: Janinah Baclaocos
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology & Dr John Mackrill, Department of Physiology
Structural basis of translational recoding
PhD Candidate: Pramod Bhatt
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
Investigation of mechanisms by which PINK1 protects against Parkinson’s disease: to develop better biomarkers and treatment targets for the disease
PhD Candidate: Rachel Furlong
Supervisor: Dr Cora O’Neill, School of Biochemistry and Cell Biology
The host response towards Bifidobacteria breve
PhD Candidate: Ana Hickey
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology & Professor Douwe Van Sinderen, School of Microbiology
Self-assembling protein-based nanoparticle biosensors for microscopy imaging
PhD Candidate: Neil O’Donnell
Supervisor: Dr Ruslan Dmitriev & Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Investigation of the role of the brain ↔ gut axis in the pathophysiology of Parkinson’s disease
PhD Candidate: Sarah O’Donovan
Supervisor: Dr Cora O’Neill, School of Biochemistry and Cell Biology
The investigation of putative recoding events in Streptomyces
PhD Candidate: Sinead O’Loughlin
Supervisor: Professor John Atkins & Professor Pasha Baranov, School of Biochemistry and Cell Biology
Investigation of the TNF superfamily of ligands as potential therapeutic targets in Inflammatory Bowel Disease (IBS)
PhD Candidate: Subhasree Rajaram
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology
The function of phosphorylated Y1250/Y1251 for IGF-1 Receptor activity, signalling and turnover
PhD Candidate: Leonie Reiger
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
The effects of Insulin-like Growth Factor-1 signalling on mitochondrial function and maintenance in cancer cells
PhD Candidate: Sarah Riis
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Investigating the association between long non-coding RNAs and ductal carcinoma in situ (DCIS)
PhD Candidate: Julia Samson
Supervisor: Dr Kellie Dean, School of Biochemistry and Cell Biology
Systemic dissemination of commensal bacteria from gut to other non-intestinal tissues
PhD Candidate: Sreeram Udayan
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology & Professor Paul O’Toole, School of Microbiology
2016 Postgraduate Seminars
An investigation of the role of Rab11A and Rab11B in EGFR endosomal trafficking
PhD Candidate: Patrycja Artemiuk
Supervisor: Professor Mary McCaffrey, School of Biochemistry and Cell Biology
Investigation of the underlying mechanisms of stop codon UGA read-through
PhD Candidate: Janinah Baclaocos
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology & Dr John Mackrill, Department of Physiology
Obtaining ribosomal complexes for structural insights into the mechanism of translational frameshifting
PhD Candidate: Pramod Bhatt
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
Investigation of mechanisms by which PINK1 protects against Parkinson’s disease: to develop better biomarkers and treatment targets for the disease
PhD Candidate: Rachel Furlong
Supervisor: Dr Cora O’Neill, School of Biochemistry and Cell Biology
Translation termination in diverse ciliates depends on stop codon proximity to 3’ polyA tails
PhD Candidate: Stephen Heaphy
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
The Host Response towards Bifidobacteria breve UCC2003
PhD Candidate: Ana Hickey
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology & Professor Douwe Van Sinderen, School of Microbiology
G-quadruplex mediated translation regulation and ribosome pause detection
PhD Candidate: Romika Kumari
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
Subcellular localisation of the FLT3-ITD oncogene and NOX4 is critical in the production of pro-survival reactive oxygen species in acute myeloid leukaemia
PhD Candidate: Jennifer Moloney
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Self-assembling protein-based nanoparticle biosensors for microscopy imaging
PhD Candidate: Neil O’Donnell
Supervisor: Dr Ruslan Dmitriev & Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Investigation of the role of the brain-gut axis in the pathophysiology of Parkinson’s disease
MSc Candidate: Sarah O’Donovan
Supervisor: Dr Cora O’Neill, School of Biochemistry and Cell Biology
The investigation of putative recoding events in Streptomyces
PhD Candidate: Sinead O’Loughlin
Supervisor: Professor John Atkins & Dr Pasha Baranov, School of Biochemistry and Cell Biology
Progesterone analog-mediated Redox response enhances cell survival in stressed 661W photoreceptor cells
PhD Candidate: Ana Ruiz Lopez
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Identification of the molecular pathways that mediate cytokine-induced immunopathology of the gut epithelium
PhD Candidate: Nisha Saini
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology
Mechanisms of immune tolerance in mice
PhD Candidate: Sreeram Udayan
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology & Professor Paul O’Toole, School of Microbiology
2015 Postgraduate Seminars
An investigation of the role of Rab11A and Rab11B in EGFR endosomal trafficking
PhD Candidate: Patrycja Artemiuk
Supervisor: Professor Mary McCaffrey, School of Biochemistry and Cell Biology
Isolation and characterization of Selenoprotein P: A multiple Selenocysteine-containing protein in Crassostrea gigas
PhD Candidate: Janinah Baclaocos
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology & Dr John Mackrill, Department of Physiology
Obtaining ribosomal complexes for structural insights into the mechanism of translational frameshifting
PhD Candidate: Pramod Bhatt
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
IGF1 inducible mitochondrial nucleotide carrier PNC1, regulates invasiveness in breast cancer
PhD Candidate: Michael Coleman
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Widespread abrogation of triplet translation continuity and stop codon mediated termination in Euplotes ciliates
PhD Candidate: Stephen Heaphy
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
Host response towards Bifidobacteria breve UCC2003 and the effect of sortase-dependent pili on this interaction
PhD Candidate: Ana Hickey
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology & Professor Douwe Van Sinderen, School of Microbiology
Use of PLIM imaging to investigate the effect of oxygen on the expression of SPCA2
PhD Candidate: James Jenkins
Supervisor: Dr Ruslan Dmitriev & Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Luminescent optical oxygen sensors with food packaging applications
PhD Candidate: Caroline Kelly
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
G-quadruplex mediated translation regulation
PhD Candidate: Romika Kumari
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
Mislocalized activation of FLT3-ITD induces the production of reactive oxygen species in MV4-11 cells
PhD Candidate: Jennifer Moloney
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Computational analysis of ribosome profiling data in order to examine short term translation response
PhD Candidate: Patrick O’Connor
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
Nanoparticle biosensors for imaging
PhD Candidate: Neil O’Donnell
Supervisor: Dr Ruslan Dmitriev & Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Recoding in Streptomyces
PhD Candidate: Sinead O’Loughlin
Supervisor: Professor John Atkins & Dr Pasha Baranov, School of Biochemistry and Cell Biology
Neurotrophic factor profile in mouse retina following stress and treatment with Norgestrel
PhD Candidate: Ana Ruiz Lopez
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Identification of the molecular pathways that mediate cytokine-induced immunopathology of the gut epithelium
PhD Candidate: Nisha Saini
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology
Understanding the role of TLR2 in inflammation using TLR2 knockout mice as a model system
PhD Candidate: Sreeram Udayan
Supervisor: Dr Ken Nally, School of Biochemistry and Cell Biology & Professor Paul O’Toole, School of Microbiology
Elucidating the mechanism of action behind the neuroprotective compound ‘Norgestrel’ in the treatment of stressed photoreceptor cells
PhD Candidate: Alice Wyse Jackson
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
2014 Postgraduate Seminars
Investigation of the role of PDLIM2 in breast cancer metastasis and tumor microenvironment regulation
PhD Candidate: Milán Bustamante Garrido (PhD Scholars Programme in Cancer Biology)
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Characterisation of presenilins in innate immune receptor signalling
PhD Candidate: Caroline Coleman
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
IGF1 inducible mitochondrial nucleotide carrier PNC1, regulates invasiveness in breast cancer
PhD Candidate: Michael Coleman
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Altered regulation of adipogenesis in disease process
PhD Candidate: Stephanie Davies (PhD Molecular and Cell Biology)
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
Presenilin ubiquitination and CUE domain function
PhD Candidate: Stephen Duggan
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Ribosomal frameshifting is a standard feature of translation in Euplotes ciliates
PhD Candidate: Stephen Heaphy
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
New systems for oxygen imaging in tissues
PhD Candidate: James Jenkins
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Novel optical oxygen sensors for smart food packaging systems
PhD Candidate: Caroline Kelly
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Role of RNA G-quadruplexes role in translation
PhD Candidate: Romika Kumari
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
Cellular regulation of the ubiquitin conjugating enzyme Ubc6
PhD Candidate: Selina Lam (PhD Scholars Programme in Cancer Biology)
Supervisor: Dr Eoin Fleming, School of Biochemistry and Cell Biology
LNX1 and LNX2 in the nervous system: a study of molecular interactions and regulation of expression
PhD Candidate: Joan Lenihan
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Investigation of the role of Trib2 in T-cell development and T-ALL
PhD Candidate: Kai-Ling Liang
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
IGF-1R signalling is essential for mitochondrial maintenance and function
PhD Candidate: Amy Lyons (PhD Molecular and Cell Biology)
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Alpha-Actinin: characterisation and synthetic biology applications
PhD Candidate: Anita Murphy
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Characterisation of the role of ST2/IL-33 in colon cancer
PhD Candidate: Charlotte O'Donnell
Supervisor: Dr Aileen Houston, Department of Medicine
Oxygen and glucose deprivation induces both global and gene-specific alterations in mRNA translation within 20 minutes
PhD Candidate: Patrick O’Connor
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
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PhD Candidate: Sandra O'Shea
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Investigating the effect of 5'UTR on translational efficiency and mTOR inhibition
PhD Candidate: Anjali Pai (PhD Scholars Programme in Cancer Biology)
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
The effect of Isoellipticines on leukaemia
PhD Candidate: Eileen Russell (PhD Molecular and Cell Biology)
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Development of tumour therapy and imaging strategies utilising bacteria
PhD Candidate: Mike Stanton (PhD Scholars Programme in Cancer Biology)
Supervisor: Dr Mark Tangney, Cork Cancer Research Centre
Investigating the potential role of GRAB as a Guanine Exchange Factor (GEF) for Rab8 and Rab3 and the functional outcome of these interactions
PhD Candidate: Jennifer Timoney (PhD Scholars Programme in Cancer Biology)
Supervisor: Professor Mary McCaffrey, School of Biochemistry and Cell Biology
Using ribosomal profiling to study translation regulation
PhD Candidate: Ioanna Tzani (PhD Scholars Programme in Cancer Biology)
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
Neuroprotection of retinal photoreceptors
PhD Candidate: Alice Wyse Jackson
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
2013 Postgraduate Seminars
Investigation of the role of PDLIM2 in colorectal cancer metastasis and tumor microenvironment regulation
PhD Candidate: Milán Bustamante Garrido (PhD Scholars Programme in Cancer Biology)
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Gene 60 Bypassing: The Nascent Peptide Effect
PhD Candidate: Arthur Coakley
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
A study of the role of presenilins in the innate immune response
PhD Candidate: Caroline Coleman
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
IGF1 inducible mitochondrial nucleotide carrier PNC1, regulates invasiveness in breast cancer
PhD Candidate: Michael Coleman
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Altered regulation of adipogenesis in disease processes
PhD Candidate: Stephanie Davies (PhD Molecular and Cell Biology)
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
Presenilin Ubiquitination and gamma-secretase activity
PhD Candidate: Stephen Duggan
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Proteomics approaches to environmental stress in Mytilus edulis due to emerging classes of anthropogenic pollutants
PhD Candidate: Tahirah Ja'Afar
Supervisor: Professor David Sheehan, School of Biochemistry and Cell Biology
Measurement of cell respiration and oxygenation with novel phosphorescent probes
PhD Candidate: Alina Kondrashina
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Steady state expression of the human ubiquitin conjugating enzyme Ubc6 (UBE2J2) is regulated by JNK and P38 MAP kinase signalling pathways
PhD Candidate: Selina Lam (PhD Scholars Programme in Cancer Biology)
Supervisor: Dr Eoin Fleming, School of Biochemistry and Cell Biology
LNX1 and LNX2 function in the central nervous system: A Study of Molecular Interactions
PhD Candidate: Joan Lenihan
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Title?
PhD Candidate: Kai-Ling Liang
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
IGF-1R Signalling Is Essential for Mitochondrial Maintenance and Function
PhD Candidate: Amy Lyons (PhD Molecular and Cell Biology)
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Nano-Meccano: Using Protein-Based Elements as Building Blocks to Generate Synthetic Nanostructures
PhD Candidate: Anita Murphy
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
The Potential Role of ST2 and its Ligand IL-33 In colon carfinogenesis
PhD Candidate: Charlotte O'Donnell
Supervisor: Dr Aileen Houston, Department of Medicine
Phosphorylation of Critical Tyrosine residue Y1250 in the C terminal Domain of IGF-1R is dependent on IGF-1
PhD Candidate: Sandra O'Shea
Supervisor: Professor Rosemary O'Connor, School of Biochemistry and Cell Biology
Investigation of the mechanism of TOP genes regulation at the level of translation
PhD Candidate: Anjali Pai (PhD Scholars Programme in Cancer Biology)
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
Isoellipticines: Novel Molecules for the Treatment of Leukaemia
PhD Candidate: Eileen Russell (PhD Molecular and Cell Biology)
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Nox4-generated H2O2 translocates to the nucleus to cause DNA oxidation and DNA double strand breaks in FLT3-ITD AML
PhD Candidate: Joanna Stanicka
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Development of tumour therapy and imaging strategies utilising bacteria
PhD Candidate: Mike Stanton (PhD Scholars Programme in Cancer Biology)
Supervisor: Dr Mark Tangney, Cork Cancer Research Centre
Investigating a novel interaction and the functional relationship between Rab25 and TGF Beta Receptor I in the context of cell motility and invasion
PhD Candidate: Jennifer Timoney (PhD Scholars Programme in Cancer Biology)
Supervisor: Professor Mary McCaffrey, School of Biochemistry and Cell Biology
Ribosome profiling in Merkel Cell Polyomavirus induced Merkel Cell Carcinoma
PhD Candidate: Ioanna Tzani (PhD Scholars Programme in Cancer Biology)
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
Role of mitochondrial activity and hypoxia in mitochondrial calcium turnover in colon cancer cells
PhD Candidate: Alicia Waters
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
2012 Postgraduate Seminars
Investigation of the p75 neurotrophin receptor and the role of its post-translational modifications in tumour cell motility and invasiveness
PhD Candidate: Janina Berghoff (PhD Scholars in Cancer Biology Programme)
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Presenilin and Regulated Intramembrane Proteolysis of Interleukin-1 receptor, type 1 and Tumor Necrosis Factor (TNF) receptor-1
PhD Candidate: Jyoti Chhibber
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Identifying the nature of reading frame transitions observed in prokaryotic genomes
PhD Candidate: Arthur Coakley
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
The effect of oxidative stress on the iron regulatory HFE protein and the ubiqutin-conjugating enzyme Ubc6e
PhD Candidate: Louise Foley
Supervisor: Dr Eoin (John) Fleming, School of Biochemistry and Cell Biology
Proteomics approaches to environmental stress in Mytilus edulis due to emerging classes of anthropogenic pollutants
PhD Candidate: Tahirah Ja’Afar
Supervisor: Professor David Sheehan, School of Biochemistry and Cell Biology
Monitoring of cell oxygenation with new phosphorescent based probes and techniques
PhD Candidate: Alina Kondrashina
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
Observation of dually decoded regions of the human genome using ribosome profiling data
PhD Candidate: Audrey Michel
Supervisor: Dr Pasha Baranov and Professor John Atkins, School of Biochemistry and Cell Biology
Functional consequence of FIP3 interactions with the dynein motor complex
MSc Candidate: Sylvia O’Sullivan
Supervisor: Professor Mary McCaffrey, School of Biochemistry and Cell Biology
Elucidation of the role of Evi5 in the Rab11/Rab25 mediated endosomal trafficking and cell migration events
MSc Candidate: Lydia Riordan
Supervisor: Professor Mary McCaffrey, School of Biochemistry and Cell Biology
Assessment of contribution of key metabolites to cell bioenergetics, responses to stimulation and hypoxia
PhD Candidate: Alicia Waters
Supervisor: Professor Dmitri Papkovsky, School of Biochemistry and Cell Biology
A nascent peptide stimulates the regulatory frameshifting on antizyme mRNA
PhD Candidate: Martina Yordanova
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology
2011 Postgraduate Seminars
A novel role of Presenilin2 in determining IL1β and LPS mediated responsiveness and gene regulation
PhD Candidate: Vishal Agrawal
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
The regulation of NF-κB by Promyelocytic Leukaemia (PML) protein
PhD Candidate: Abrar Ahmed
Supervisor: Dr Ruaidhri Carmody, School of Biochemistry and Cell Biology
The SREBP Pathway in Cancer
PhD Candidate: Kathy Barriscale
Supervisor: Professor Tommie McCarthy, School of Biochemistry and Cell Biology
Investigation of p75 neurotrophin receptor and the role of its post-translational modifications in tumour cell motility and invasiveness
PhD Candidate: Janina Berghoff
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Development of an integrated microfluidic system for genetic analysis
PhD Candidate: Desmond Brennan
Supervisor: Dr Paul Galvin, ASSERT for Health Research Group, UCC
Targeting regulatory T cells in cancer
PhD Candidate: William Byrne
Supervisor: Professor Gerry O’Sullivan, Cork Cancer Research Centre
Presenilin and regulated intramembrane proteolysis of Interleukin-1 receptor, type 1
PhD Candidate: Jyoti Chhibber
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Investigation of the molecular determinants of NF-κB p50 ubiquitination
PhD Candidate: Patricia Collins
Supervisor: Dr Ruaidhri Carmody, School of Biochemistry and Cell Biology
FLT3-driven redox signalling in acute myeloid leukemia
PhD Candidate: Aoife Corcoran
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Investigating the function of heme-binding protein HRG-1 in pH equilibrium and invasive cancer cells
PhD Candidate: Fionola Fogarty
Supervisor: Professor Rosemary O’Connor, School of Biochemistry and Cell Biology
Investigation of the role of the α-actinin family of actin-binding proteins in cell adhesion and motility
PhD Candidate: Kate Foley
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
The effect of oxidative stress on the iron regulatory HFE protein
PhD Candidate: Lousie Foley
Supervisor: Dr Eoin (John) Fleming, School of Biochemistry and Cell Biology
Regulation of TRIB2 gene expression in normal and AML Cells
PhD Candidate: Maura Hannon
Supervisor: Dr Karen Keeshan, School of Biochemistry and Cell Biology
Investigating IRS/RACK1 complexes in IGF-IR pathway in cancer cells
PhD Candidate: Catherine Harrington
Supervisor: Professor Rosemary O’Connor, School of Biochemistry and Cell Biology
A SLICK technique for the study of neuronal activity-dependent competition
PhD Candidate: Victoria Heimer-McGinn
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Redox effects on sub-proteomes targeted by oxidative stress
PhD Candidate: Wentao Hu
Supervisor: Professor David Sheehan, School of Biochemistry and Cell Biology
Development of public databases and large-scale analysis of RNA editing in humans
PhD Candidate: Anmol Kiran
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
The interactions of Nox4 and Bcr-Abl in the survival of leukaemia cells
PhD Candidate: William Landry
Supervisor: Professor Tom Cotter, School of Biochemistry and Cell Biology
Mechanism of Trib2 mediated degradation of C/EBP-α in Acute Myelogenous Leukaemia
PhD Candidate: Fiona Lohan
Supervisor: Dr Karen Keeshan, School of Biochemistry and Cell Biology
Development of a computational technique to detect reading frame transitions using ribo-seq data
MSc Candidate: Audrey Michel
Supervisor: Dr Pasha Baranov and Professor John Atkins, School of Biochemistry and Cell Biology
Regulation of LPS tolerance in macrophages
PhD Candidate: Christine O’Carroll
Supervisor: Dr Ruaidhri Carmody, School of Biochemistry and Cell Biology
Investigating the role of PTEN-induced Kinase 1 in cancer development and pathogenesis
PhD Candidate: Ciara O’Flanagan
Supervisor: Dr Cora O’Neill, School of Biochemistry and Cell Biology
Pregnancy-Specific Glycoproteins: search for a receptor mediating pro-angiogenic and immunomodulatory properties
PhD Candidate: Ronan O’Riordan
Supervisor: Dr Tom Moore, School of Biochemistry and Cell Biology
Proteomic approach of oxidative stress in Daphnia magna
PhD Candidate: Louis Charles Rainville
Supervisor: Professor David Sheehan, School of Biochemistry and Cell Biology
Analysis of expression and function of LNX1 and LNX2 in the central nervous system
PhD Candidate: Orthis Saha
Supervisor: Dr Paul Young, School of Biochemistry and Cell Biology
Analysis of evolutionary conserved recoded genes in bacteria
PhD Candidate: Virag Sharma
Supervisor: Dr Pasha Baranov, School of Biochemistry and Cell Biology
NF-κB p105 and IκBγ are nucleocytoplasmic shuttling proteins
PhD Candidate: Jamie Urquhart
Supervisor: Dr Ruaidhri Carmody, School of Biochemistry and Cell Biology
TRAF6-mediated ubiquitination of the γ-secretase protease complexes and its substrates
PhD Candidate: Run Yan
Supervisor: Dr Justin McCarthy, School of Biochemistry and Cell Biology
Nascent peptide can stimulate translational frameshifting
PhD Candidate: Martina Yordanova
Supervisor: Professor John Atkins, School of Biochemistry and Cell Biology