Thiele Lab

Prof Ines Thiele is the principal investigator of the Molecular Systems Physiology group and Director of the Digital Metabolic Twin Centre at the University of Ireland, Galway.  Prof Ines Thiele is also a principal investigator at APC Microbiome Ireland and a Co-Principal Investigator on Theme 2, Diet and Microbes. 

Her research aims to improve the understanding of how diet influences human health. Therefore, she uses a computational modelling approach, termed constraint-based modelling, which has gained increasing importance in systems biology.

Her group builds comprehensive models of human cells and human-associated microbes; then employs them together with experimental data to investigate how nutrition and genetic predisposition can affect one's health. In particular, she is interested in applying her computational modelling approach for better understanding of inherited and neurodegenerative diseases. Ines Thiele has been pioneering models and methods allowing large-scale computational modelling of the human gut microbiome and its metabolic effect on human metabolism.

In 2013, Ines Thiele received the ATTRACT fellowship from the Fonds National de la Recherche (Luxembourg). In 2015, she was elected as EMBO Young Investigator. In 2017, she was awarded the prestigious ERC starting grant. In 2018, she was an awardee of the NUI Galway Foundation Research Leadership Programme. She is also a reviewer for multiple journals and funding agencies.