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January 2015

January 2015

January 2015:  Confocal Laser Scanning Microscope  Image projection of serial Z series sections.

Submitted by Dr Holly Greene, recent graduate from Department of Anatomy and Neuroscience.

TLX (orphan nuclear receptor tailless homologue) maintains adult neural stem cells in an undifferentiated, proliferative state. TLX (red) can silence glia-specific expression of the astrocyte marker GFAP (green) in neural stem cells, suggesting that transcriptional repression may be crucial in maintaining the undifferentiated state of these cells. Nuclei are stained blue with DAPI. Notice cell preparing to divide.

Click here for movie of Z series through the specimen

JANUARY 2015 VIDEO

Department of Anatomy and Neuroscience

Anatamaíocht agus Néareolaíocht

Room 2.33, 2nd Floor, Western Gateway Building, University College, Cork, Ireland

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