BioIT Platform

Bacterial genome sequences provide definitive information for investigating biological properties and understanding the role of the microbiota in health and disease. The BioIT platform provides expertise in genomics, transcriptomics and metagenomics, and the interpretation of associated data sets.

Tools/equipment/techniques:

Various ‘omics’ analyses & associated bioinformatics

Global gene expression (transcriptomics, microarrays)

Standardized microarray procedures (2x11k & 4x44k)

Multispecies arrays

Bifidobacterium species

Helicobacter pylori

Lactobacillus salivarius

Lactococcus lactis

Human

Array-based techniques

Expression analysis

Genomic content (CGH)

Genome sequencing/analysis

Assembly, annotation (ERGO platform) and comparative analysis

Identifying relevant biological processes (e.g. metabolic pathways)

Statistics, clustering & visualization

Platform leaders: Douwe van Sinderen, Aldert Zomer

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