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Book of Modules 2012/2013 |
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BMXXXX |
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Credit Weighting: 5
Teaching Period(s): Teaching Period 1.
No. of Students: Max 40.
Pre-requisite(s):
Co-requisite(s): None
Teaching Methods: 18 x 1hr(s) Lectures; 6 x 2hr(s) Practicals.
Module Co-ordinator: Dr Collette Hand, Department of Pathology.
Lecturer(s): Staff, Department of Pathology; Dr Collette Hand, Department of Pathology.
Module Objective: To provide an introduction to basic cellular pathology.
Module Content: Pathological processes including cell injury, cellular responses to injury, cellular adaptation, cell death, inflammation and repair. Neoplasia terminology and classification. Genetic and environmental causes of neoplasia. Mechanisms of disease underlying circulatory disorders.
Detailed overview of the functions and techniques of the histopathology lab. Procedures involved in the processing of patient samples to stained microscope slides. Use of specialised techniques and stains. Introduction to immunohistochemisty.
Practical classes will involve detailed study of staining techniques and quality of staining.
Learning Outcomes: On successful completion of this module, students should be able to:
· Recall pathological terminology.
· Outline cellular responses and adaptations to injury.
· Describe the pathological processes observed in inflammation, repair, neoplasia and circulatory disorders.
· Explain the systems used to classify neoplasms.
· Identify stages of sample preparation in the histopathology lab.
· Recognise commonly used histological stains and their uses.
· Assess the quality of stained slides.
· Identify procedures that affect the quality of stained slides.
Assessment: Total Marks 100: End of Year Written Examination 90 marks; Continuous Assessment 10 marks (MCQ Exam; 10 Marks).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral Examination if requried.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 1½ hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 1½ hr(s) paper(s) to be taken in Autumn. Marks in passed element(s) of Continuous Assessment are carried forward, Failed element(s) of Continuous Assessment must be repeated (MCQ Examination).
Credit Weighting: 5
Teaching Period(s): Teaching Period 1.
No. of Students: Max 30.
Pre-requisite(s): BM3001
Co-requisite(s):
Teaching Methods: 18 x 1hr(s) Lectures; 3 x 2hr(s) Practicals.
Module Co-ordinator: Dr Collette Hand, Department of Pathology.
Lecturer(s): Dr Collette Hand, Department of Pathology; Staff, Department of Pathology.
Module Objective: To understand clinicopathological features of common human diseases and the role of histopathology, cytology and molecular and immunohistochemical techniques in their investigation.
Module Content: Systemic pathology including diseases of the cardiovascular, respiratory, gastrointestinal, hepatobiliary, neurological, and renal systems and diseases of skin, breast, blood and bone marrow.
Special techniques including immunohistochemistry, electron microscopy and special stains. Molecular Pathology, quality control and validation. Cytology. Practical-based diagnostic cases encourage a practical understanding of cellular pathology practice.
Learning Outcomes: On successful completion of this module, students should be able to:
· Outline the common diseases of the cardiovascular, respiratory, gastrointestinal, hepatobiliary, neurological, and renal systems and diseases of skin, breast and genitourinary tract.
· Associate cellular changes observed with the disease process.
· Propose an appropriate testing protocol for investigation of samples
· Describe the molecular techniques employed in histopathology labs.
· Indicate the use of specialised techniques.
· Review the key concepts of quality control and assessment in a laboratory setting.
Assessment: Total Marks 100: End of Year Written Examination 90 marks; Continuous Assessment 10 marks (MCQ Exam; 10 Marks).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral examination, if required.
Penalties (for late submission of Course/Project Work etc.): None.
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 1½ hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 1½ hr(s) paper(s) to be taken in Autumn. Marks in passed element(s) of Continuous Assessment are carried forward, Failed element(s) of Continuous Assessment must be repeated (MCQ Examination).
Credit Weighting: 15
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Max 25.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: Other (16 weeks of Laboratory Work plus independent library research).
Module Co-ordinator: Dr Sinead Kerins, Department of Biochemistry.
Lecturer(s): Staff, Cork Institute of Technology.
Module Objective: To carry out an independent research project on a biomedical science topic.
Module Content: The project requires students to research an area of interest in Biomedical Science, plan and execute a programme of investigative work, write a concise scientific report and present the work in the form of a seminar to the class.
Learning Outcomes: On successful completion of this module, students should be able to:
· Demonstrate understanding of the basis and application of laboratory methods and techniques in Biomedical Science and demonstrating competence in performing these in Biomedical Science.
· Design, plan, execute, interpret the data from, and report on an independent research project.
· Source, review, critically assess and evaluate scientific literature relevant to an independent research project.
· Demonstrate the appropriate writing and oral communication skills for presentation of an independent research project.
Assessment: Total Marks 300: Continuous Assessment 300 marks (Research Thesis. Oral, if required).
Compulsory Elements: Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: No End of Year Written Examination.
Requirements for Supplemental Examination: No Supplemental Examination.
BM6001 Molecular and Cellular Biology and Related Technologies.
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Paul Young, Department of Biochemistry.
Lecturer(s): Staff, Department of Biochemistry, and guest lecturers.
Module Objective: To provide an overview of the cell at molecular and cellular level and to provide an understanding of current technologies in molecular and cellular biology.
Module Content: A detailed overview of molecular and cellular biology including biomolecules, metabolism, protein function, DNA and chromosomes, gene regulation, membrane structure and function, organelles, cell communication, cell survival and cell death, cell division, genomics, proteomics, DNA technology.
What is in the human genome ?
Chromatin remodeling and gene transcription - role in cancer and other diseases
Protein structure, expression and degradation - involvement in degenerative diseases
Diagnostic Molecular Genetics - technologies and their ethical implications
Diagnostic Molecular Genetics - regulatory and ethical implications
Applications of PCR in clinical diagnostics
Applications of in situ hybridization in a Diagnostic Laboratory
DNA Microarrays in tumor profiling
Applications of proteomics in biomedical science
Genomic analysis of multifactorial diseases
Pharmacogenomics, Pharmacogenetics and Personalised Medicine
Advances in single nucleotide polymorphism (SNP) analysis.
Learning Outcomes: On successful completion of this module, students should be able to:
· Outline recent advances in our understanding of gene expression and protein turnover.
· Review the molecular mechanisms of cell division, cell death and cell signaling.
· Compare the cellular and molecular mechanisms underlying selected disease states.
· Integrate the principles of molecular biology and their application in diagnostics.
· Discuss advances in proteomics and genomics and their impact on biomedical science.
· Analyze relevant primary literature and summarize material for presentation to peers.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Essay: 20 marks; Group work: 20 marks; In Class Test: 20 marks) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral if required)).
BM6002 Research Methods in Biomedical Sciences
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Martina Scallan, Department of Microbiology.
Lecturer(s): Staff, Department of Microbiology, and guest lecturers.
Module Objective: To provide a detailed appraisal of research methods in Biomedical Science.
Module Content: Research methodology; project and experimental design; statistical planning and analysis; evidence-based medicine; clinical audit; risk assessment; legal and ethical issues in biomedical research; scientific communication; scientific assessment and review.
Learning Outcomes: On successful completion of this module, students should be able to:
· Communicate legal and ethical issues in biomedical research.
· Overview the stages of a research project from proposal through to publication, and processes used to evaluate the research.
· Demonstrate written and oral scientific communication skills.
· Perform appropriate statistical analyses on biomedical data.
· Give an account of evidence-based medicine and clinical audit.
· Describe key apects of risk assessment in hospital laboratories.
· Develop and implement a research project.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (1 x written report of 3,000 words (Oral, if required)).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. Marks in passed element(s) of Continuous Assessment are carried forward, Failed element(s) of Continuous Assessment must be repeated (as specified by module coordinator. (Oral if required)).
BM6003 The Molecular Basis of Disease
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 20, Max 10.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case Studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Collette Hand, Department of Pathology.
Lecturer(s): Staff, Department of Pathology, and guest lecturers.
Module Objective: To provide a comprehensive understanding of the molecular basis of disease.
Module Content: A detailed overview of molecular pathophysical aspects of disease including biochemical, immunological and molecular physiological aspects.
Disease gene identification and use of the human genome
Immunology and Transplantation
Molecular Basis of Neoplasia
Selected Diseases and Mechanisms:
Cardiovascular Disease, Diabetes, Genomic Imprinting, Ion Channels and Disease, Muscle Diseases, Neurodegeneration, Thrombosis and Haemostasis.
Use of Molecular Knowledge for Diagnosis
Molecular Mechanisms of Microbial Pathogenesis
Learning Outcomes: On successful completion of this module, students should be able to:
· Identify diseases with a significant molecular basis.
· Describe molecular mechanisms responsible for common diseases.
· Demonstrate how inheritance of mutated genes leads to pathology either in childhood or in later life.
· Interpret how the life style of an individual or his/her environment can give rise to genetic or physiological change within the adult cell that results in diseases.
· Discuss how rational design of novel technologies can arise from knowledge of the molecular basis of disease.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Report: 60 marks) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. Marks in passed element(s) of Continuous Assessment are carried forward, Failed element(s) of Continuous Assessment must be repeated (Oral, if required).
BM6004 Laboratory Management in Biomedical Science
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments); Seminars.
Module Co-ordinator: Dr Paul Young, Department of Biochemistry (Dr. Brendan O'Connell (CIT)).
Lecturer(s): Staff, Cork Institute of Technology, and guest lecturers.
Module Objective: To provide a systematic understanding of the principles and methods used in laboratory management.
Module Content: Principles of management, quality assurance management, quality assesment, accreditation and current good laboratory practices, resource management, and health care research.
Management Theories:
Scientific management, bureaucracy, human relations perspective, quantitative management perspective, contingency management perspective, human resource management, personnel management versus human resource management.
Planning and Decision-Making:
Levels of planning, organisational goals, barriers to planning, management by objectives,
decision-making,models of decision making, decision-making process, group decision making, stategic management and planning, project management.
Motivation:
Motivational theories, motivation at work, motivation and work behaviour, needs and motives in
organisations, psychological contract.
Performance Management:
Managing individual performance, poor performance, performance appraisal versus performance management, rewarding performance, ethics of managing performance.
Teamwork and Communication Skills:
Individual differences,dynamics of groups and teams at work, managing teams, types of communication in organisations, presentation skills, barriers to effective communication, chairing meetings.
Managing People:
Recruitment, selection, training, development, managing of work-related stress, leading and leadership,
leadership versus management, continuous professional development, managing change.
Health Service Executive:
Overview of HSE,budget allocation, policy reform documents, challenges facing todays health care managers.
Employment Law:
Overview of Irish legal system, labour law institutions, appeals tribunal, labour court, equality, contracts and conditions, termination and protective legislation.
Role of Professional Body:
Current and future roles, voluntary registration, statuttory registration and the 2005 Act, self regulation, continuing professional development , profession ethics.
Medical Law
Learning Outcomes: On successful completion of this module, students should be able to:
· Recognise the contribution of human resource management activities to the overall functioning of organisations.
· Appreciate the similarities and differences between various management perspectives.
· Discuss the evolving Irish Health Service
· Establish how clinical goverance is a framework through which the health organisation is accountable for its practices.
· Outline the role of financial management in the clinical laboratory.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Group work: 30 marks; In Class Presentation: 30 marks) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral if required)).
BM6005 Research Project in Biomedical Science
Credit Weighting: 30
Teaching Period(s): Teaching Periods 1 and 2 and Teaching/Research Period 3.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 18 x 1month(s) Directed Study (Independent Supervised Project work).
Module Co-ordinator: Dr Paul Young, Department of Biochemistry.
Lecturer(s): Staff, Department of Biochemistry, and guest lecturers.
Module Objective: To carry out a research project on a biomedical problem.
Module Content: The project requires students to research an area of interest in Biomedical Science, plan and execute a programme of investigative work, write a scientific report and present the work in the form of a seminar to the class. The research work carried out is expected to be of a standard that is at least publishable in part in a journal in the biomedical science area.
Learning Outcomes: On successful completion of this module, students should be able to:
· Conduct independent research informed by a critique of empirical literature in the field of Biomedical sciences.
· Consider and take appropriate measures to ensure compliance with ethical and health and safety legal requirements.
· Initiate, design, undertake and critically appraise an advanced study.
· Critically assess the outcome and place in broader context the significance of research findings.
· Demonstrate the appropriate written and oral communication skills required of the professional practitioner.
Assessment: Total Marks 600: Continuous Assessment 600 marks (Research Project).
Compulsory Elements: Continuous Assessment.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: No End of Year Written Examination.
Requirements for Supplemental Examination: No Supplemental Examination.
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Paul Young, Department of Biochemistry ( Mr. Michael Healy, CIT).
Lecturer(s): Staff, Cork Institute of Technology, and guest lecturers.
Module Objective: To provide an in-depth understanding of scientific knowledge of Haematology.
Module Content: Stem cell biology, gene transfer systems and clinical applications, nutritional anaemias, haemoglobinopathies, inherited haemolytic anaemia, tropical diseases, leukaemogenesis, endothelial cell function and haemostasis, haemostatic disorders, thrombosis and thrombophilia.
Megaloblastic Anaemia
Hypochromic Anaemia
Haemolytic Anaemia
Genetic Disorders of Haemoglobin
Haematological aspects of Tropical Diseases
The aethiology and genetics of Haematologcal Malignancies.
The classification of Haematological Malignancies.
The clinical and laboratory diagnosis of Haematological Malignancies
The management of Haematological Malignancies
Benign White Cell Disorders
Haemostasis and the Laboratory Interface
Platelets and platelet disorders
The Inherited and Acquired Coagulation Disorders
Vascular Disorders
Thrombosis and Thrombophilia
Anticoagulation and other Therapeutics used in Thrombosis
Haematological Aspects of Tropical Disease
Learning Outcomes: On successful completion of this module, students should be able to:
· Integrate patient clinical findings and laboratory results to classify anaemias.
· Critically evaluate patient details and laboratory results with a view to understanding and classifying haematological malignancies.
· Have a clear understanding of Haemostasis and Thrombosis and the associated clinical disorders.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (3 x Essay 20 marks each) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral if required)).
BM6008 Advanced Transfusion Service
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Paul Young, Department of Biochemistry (Mr. Michael Healy , CIT).
Lecturer(s): Staff, Cork Institute of Technology, and guest lecturers.
Module Objective: To provide an in-depth understanding of the scientific knowledge of Transfusion Science.
Module Content: Blood group systems, antibody resolution, computers and transfusion medicine, ante-natal serology, platelet and neutrophil serology, tissue banking, blood processing, blood substitutes.
EU Blood Directive and Quality Assurance
Haemovigilance
Blood Group Systems
Pretransfusion Testing and Red cell antibody resolution
Aspect of Donor and Patient Blood Grouping
Auto Immune Haemolytic Anaemia
Clinical Aspects of Blood Transfusion
Donor recruitment and Blood Processing
Microbiological Testing of Blood
Clinical and Laboratory Aspects of Ante-Natal Serology
Tissue Transplantation
Platelet and Neutrophil Serology
Tissue Banking
Blood Substitutes and Genetic Engineering
Transfusion Information Systems
Learning Outcomes: On successful completion of this module, students should be able to:
· Have a clear understanding of the quality standards and directives that pertain to transfusion science.
· Have an in depth knowledge of the different blood group systems and be able to critically evaluate serological results to aid in identifying red cell antibodies and elucidate other serological anomalies and problems.
· Identify and understand the roles of the transfusion establishments in providing a transfusion service.
· Integrate clinical and laboratory aspects of transfusion science with a view to understanding safe transfusion practice.
· Analyse, interpet and communicate medical and scientific papers, case studies and literature reviews to ones peers.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (2 x Essay 20 marks each; Case Study: 20 marks) Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral if required)).
BM6009 Advanced Microbial Pathogenesis
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments); Seminars.
Module Co-ordinator: Dr John G. Morgan, Department of Microbiology.
Lecturer(s): Staff, Department of Microbiology, and guest lecturers.
Module Objective: To provide a detailed understanding of microbial disease and the underlying pathogenic mechanisms.
Module Content: Virulence, evasion of the host immune system, exotoxins, resistance to antimicrobials, viral pathogenesis.
Specific examples of pathogenesis.
Learning Outcomes: On successful completion of this module, students should be able to:
· Demonstrate an advanced expertise in microbial pathogenesis.
· Use case studies to illustrate principles of microbial pathogenesis.
· Understand the scientific method.
· Demonstrate a knowledge of the molecular biology methodologies required for the study of microbial pathogens.
· Undertake self-directed learning.
· Understand that scientific research requires creativity and imagination and questioning.
· Apply skills in interpretation and critical review of scientific papers.
· Use library databases to perform a literature search.
· Research and write a review essay on a specific topic in microbial pathogenesis.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Essay: 55 marks; In class Presentation 5 marks) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral if required)).
BM6010 Diagnostic and Public Health Microbiology
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments); Seminars.
Module Co-ordinator: Dr Paul Young, Department of Biochemistry (Dr. Lesley Cotter, CIT).
Lecturer(s): Staff, Cork Institute of Technology, and guest lecturers.
Module Objective: To provide an understanding of the main activities of public health, environmental and clinical diagnostic microbiology.
Module Content: Established public health laoratory Services, Validated food, environmental and clinical diagnostic systems. Near patient testing. Emerging infections. Epidemiology. Rapid alerting methods and control of outbreaks. Sexually transmitted diseases.
Surveillance methods and applications. A network approach: EARSS
Rapid diagnostic techniques and typing
International infection control measures. A case study SARS.
Emerging and re-emerging infectious disease. Impact of foreign travel.
Sexually transmitted disease. Emerging trends and treatment strategies.
Overview of zoonotic infections
Foot and mouth disease.
Accreditation of public health laboratories.
Antibiotics versus vaccines- current trends and future.
Tracking of foodborne outbreaks.
Bioterrorism.
Mycological infections.
Enteric viral infections.
Learning Outcomes: On successful completion of this module, students should be able to:
· Integrate (or envisage integration) modern techniques such as molecular biology based strategies into current microbiological practices.
· Have a systematic understanding of the impact, surveillance and control of microbiological public health threats.
· Discuss trends of infectious disease patterns locally and globally.
· Review and critique pertinent literature and present evaluation verbally and in written formats.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Essay: 20 marks; In Class Presentation: 40 marks) Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral if required)).
BM6011 Advanced Clinical and Physiological Biochemistry
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Paul Young, Department of Biochemistry (Dr. Brendan O'Connell CIT).
Lecturer(s): Staff, Cork Institute of Technology, and guest lecturers.
Module Objective: To provide a systematic understanding of clinical biochemistry.
Module Content: Fluid and electrolyte balance, heart and cardiovascular disease, liver function in health and disease, gastrointestinal function, renal function in health and disease, free radicals in cell and organ function, cancer, neonatal toxicology and therapeutic drug monitoring.
Fluid and Electrolyte Balance
Heart and Cardiovascular Disease
Clinical Aspects of Liver and Gastrointestinal Function
Laboratory Investigation of Liver Dysfunction
Laboratory Investigation of Gastrointestinal Tract Dysfunction
Clinical Aspects of Renal Dysfunction
Laboratrory Investigation of Renal Dysfunction
The Appropriate Use of Tumour Markers in Oncology
PSA in the Diagnosis of Prostate Cancer
Inborn Errors of Metabolism
Interaction of Clinical Biochemistry Laboratory and the Pediatric Ward
Free Radicals in Cell and Organ Function
The Role of the Laboratory in Therapeutic Drug Monitoring
The Role of the Clinical Biochemistry Laboratory in Providing a Service in Toxicology
Learning Outcomes: On successful completion of this module, students should be able to:
· Integrate patient history, clinical examination details, and laboratory results to determine the fluid and electrolyte status of a patient.
· Correlate laboratory findings with the pathological processes occuring in the different diseases of the organ systems.
· Integrate metabolic pathways of toxic compounds to the laboratory investigation of disease.
· Have a systematic understanding of the biochemical abnormalities associated with tumours.
· Communicate results of literature reviews to peers and engage in critical dialogue.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Case Study: 20 marks; 2 x Essay 20 marks each) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral, if required)).
BM6012 Endocrinology and Metabolic Disease
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments); Seminars.
Module Co-ordinator: Dr Paul Young, Department of Biochemistry (Dr. Brendan O'Connell CIT).
Lecturer(s): Staff, Cork Institute of Technology, and guest lecturers.
Module Objective: To provide a systematic understanding of endocrine and metabolic disorders.
Module Content: Thyroid gland, adrenal gland, reproductive system, carbohydrate metabolism, calcium phosphate and magnesium metabolism, amino acid metabolism.
Overview of Hormone Stimulation and Regulation:
hormones, hypothalmic-pituitary-endocrine axis, control and regulation of hormone action, mechanisms of action.
Thyroid Gland:
thyroid hormones, thyroid function tests, hypothyroidism, hyperthyroidism, recent advances, case studies.
Adrenal Corex:
cortisol, adrenal androgens, aldosterone, congenital adrenal hyperplasia, hypofunction of the adrenal cortex, hyperfunction of the adrenal cortex, recent advances, case studies.
Adrenal Medulla:
overview, metabolism of catecholamines, phaeochromocytomas, recent advances, case studies
Diabetes Mellitus
classification, diagnostic criteria, glycosylated haemoglobin, obesity, recent advances, case studies.
Lipoprotein Metabolism:
overview of lipoprotein metabolism, clinical disordres of lipoprotein metabolism, recent advances, case studies.
Calcium, Phosphate and Magnesium Metabolism:
serum calcium, calcium and phosphate homeostasis, disordres of calcium phosphate and magesium metabolism, recent advances, case studies.
Amino Acid Metabolism:
overview of amino acid metabolism, disorders of amino acid metabolism, laboratory investigation, recent advances, case studies.
Investigation of Infertility:
overview of gonadal function, endocrine investigations in the subfertile woman, endocrine investigations in the subfertile man, recent advances, case studies.
Endocrine Disruption:
endocrine disrupter, overview of mechanisms of estrogen action, development of computer based predictive models, structure activity relationships for estrogen receptor.
Learning Outcomes: On successful completion of this module, students should be able to:
· Demonstrate a systematic understanding of the biochemical basis associated with endocrine and metabolic function.
· Correlate laboratory findings with the pathological processes occuring in the different diseases of the endocrine system.
· Correlate laboratory findings with the defects occuring in the different metabolic processes.
· Communicate results to peers and engage in critical dialogue.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (Case Study: 20 marks; Essay: 20 marks; In Class Presentation: 20 marks) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment.(Oral, if required)).
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Prof Thomas McCarthy, Department of Biochemistry.
Lecturer(s): Staff, Department of Biochemistry, and guest lecturers.
Module Objective: To provide a comprehensive understanding of Immunology.
Module Content: Immunoglobulins and T-cells, MHC and Antigen presentation, Lymphocyte repertoires and T- and B-cell signalling, viral and bacterial immunity, tolerance and autoimmunity.
Cells and organs of the immune system.
Antigen specificity, clonal selection and immunological memory in adaptive immunity.
Antimicrobial peptides in innate immunity.
Toll-like receptor signal transduction pathways in pathogen recognition.
Antibody structure and classification of immunoglobulins.
Rolls of the MHC complexes in antigen presentation and histocompatibility.
Organization and rearrangements of T-cell receptor genes.
Role of regulatory T-cell in tolerance and the suppression of immune responses.
Molecular mimicry and the breakdown of tolerance in autoimmunity.
Characteristics of immunodeficiency in HIV patients.
Applications of antibodies in the clinical laboratory.
Learning Outcomes: On successful completion of this module, students should be able to:
· Review the humoral and cell-mediated divisions of the immune system.
· Describe origins, differentiation and maturation of immune cells.
· Distinguish between adaptive and innate immunity and discuss the molecular and genetic mechanisms involved in adaptive immunity.
· Compare immune responses mechanisms in viral and bacterial infections.
· Delineate the mechanisms underlying detrimental immune responses in asthma, allergic reactions and autoimmunity.
· Outline the abnormalities of the immune system that cause immunodeficiency.
· Integrate the principles of immunology with the application of antibodies in clinical diagnostic tests.
· Analyze relevant primary literature and summarize material for presentation to peers.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (2 x In Class Tests 30 marks each (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment. (Oral, if required)).
BM6014 Advanced Cellular Pathology
Credit Weighting: 10
Teaching Period(s): Teaching Periods 1 and 2.
No. of Students: Min 10, Max 20.
Pre-requisite(s): None
Co-requisite(s): None
Teaching Methods: 36hr(s) Lectures; 14hr(s) Directed Study (Case studies, data analysis and relevant assignments).
Module Co-ordinator: Dr Collette Hand, Department of Pathology.
Lecturer(s): Staff, Department of Pathology, and guest lecturers.
Module Objective: To provide a detailed understanding of tissue and cellular pathology and pathogenesis of disease with molecular correlations.
Module Content: Clinicopathological features of disease including cardiovascular, respiratory, gastrointestinal, hepatic, renal, skin, male and female genital tracts and breast diseases.
Systemic pathology and investigative techniques.
Gastointestinal System.
Oesophagus and Stomach Small Intestine and Non-Neoplastic Diseases of Large Intestine. Polyps and Tumours of the Colon. Gastointestinal Gross Pathology. Liver and Gallbladder Pathology.
Kidney Pathology and special techniques used in investigation of kidney disease.
Breast Pathology.
Female Genitourinary Tract Pathology and Cytology.
Male Genitourinary Tract Pathology.
Neuropathology and Special Techniques in Neuropathology.
Lymph Node and Bone Marrow Pathology.
Cardivascular Pathology.
Immunohistochemistry.
Tecniques and uses in Diagnostic Practice.
Respiratory Pathology, Cytology and Fluids.
Skin Pathology.
Including gross pathology.
Learning Outcomes: On successful completion of this module, students should be able to:
· Identify common tissue types from microscopic slides.
· Distinguish normal and abnormal tissue samples.
· Describe disease processes in common diseases.
· Associate cellular changes observed with disease process.
· Interpret cellular changes visible on microscopic slides in the context of patient history, clinical information and laboratory results to determine the presence or absence of disease.
· Assess the disease severity and/or progression if appropriate.
· Differentiate between similar disease affecting the system/organ based on lab results.
· Propose an appropriate testing protocol for further investigation of samples if required.
Assessment: Total Marks 200: End of Year Written Examination 140 marks; Continuous Assessment 60 marks (2 x In Class Test 30 marks each) (Oral, if required).
Compulsory Elements: End of Year Written Examination; Continuous Assessment. Oral, if required.
Penalties (for late submission of Course/Project Work etc.): Work which is submitted late shall be assigned a mark of zero (or a Fail Judgement in the case of Pass/Fail modules).
Pass Standard and any Special Requirements for Passing Module: 40%.
End of Year Written Examination Profile: 1 x 3 hr(s) paper(s).
Requirements for Supplemental Examination: 1 x 3 hr(s) paper(s) to be taken in Autumn. The mark for Continuous Assessment is carried forward (Except when continuous assessment was failed overall. In this case the Supplemental Exam will incorporate assessment of both End of Year Written Examination and Continuous Assessment.(Oral, if required)).
