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Obstetrics and Gynaecology

Name: Prof. Louise Kenny
Position: Professor of Obstetrics and Consultant Obstetrician and Gynaecologist
T: 353 (0)21 420 5023
F: 353 (0)21 420 5025
E: l.kenny@ucc.ie

Prof. Louise Kenny

Biography

Louise Kenny (MB ChB (hons), PhD, MRCOG) is Professor of Obstetrics at University College Cork and a Consultant Obstetrician and Gynaecologist at Cork University Maternity Hospital.
Louise graduated in Medicine with honours from the University of Liverpool, UK, in 1993. After completing her internship and SHO training in the Mersey region, she moved to Nottingham in 1997 to undertake a research project in the School of Biomedical Sciences. In 1999 she was awarded one of the first MRC/RCOG Clinical Training Fellowships and subsequently completed a PhD investigating abnormal vascular responses in pre-eclampsia. In recognition of this body of work she was awarded the William Blair Bell Lectureship by the Royal College of Obstetricians and Gynaecologists in 2003. In 2001, she was invited to move to the Maternal and Fetal Health Research Centre, University of Manchester as a clinical lecturer. She undertook a programme of post-doctoral work at the same time as completing her clinical training in obstetrics and gynaecology and developing her interest in maternal medicine. Her post-doctoral work has mainly investigated the use of metabolomic technology in the development of a screening test for pre-eclampsia. This work attracted the Society for Gynaecological Investigation President’s Award and Plenary Presentation at the annual meeting in Los Angeles, 2005.
In 2006, Louise moved to Ireland to take up key role in the development of the new Anu Research Centre at Cork University Maternity Hospital and continued to develop her research programme in uteroplacental insufficiency, adverse pregnancy outcome and pregnancy loss. Since her appointment, Louise has raised over €4million in external awarded peer reviewed grants and has developed a research group consisting of 20 researchers from a wide variety of clinical and scientific disciplines. For further information see the group’s web pages [This will be a link to our group’s web page]
In 2007, Louise was appointed as a Health Research Board Ireland Clinician Scientist. This 4 year award (of €1.6 million) is underpinning the Screening for Pregnancy Endpoints (SCOPE) Study- a prospective longitudinal case cohort of pregnancy outcome which will also contribute to the world’s largest global pregnancy biobank (see www.scopestudy.net)
In July 2009, Louise was awarded a prestigious Principal Investigator Programme grant from Science Foundation Ireland to develop predictive metabolomic markers of poor pregnancy outcome (see link to web page). In addition she currently holds grants from The Wellcome Trust, The Children’s Medical and Research Foundation, Molecular Medicine Ireland and the Health Research Board of Ireland.
Louise’s work has resulted in >60 peer reviewed original papers, reviews and book chapters. She is the Editor of the 19th Edition of ‘Obstetrics by Ten Teachers’- the world’s leading undergraduate textbook in obstetrics. In addition, Louise is a reviewer for a wide range of international journals including the American Journal of Obstetrics and Gynecology, the British Journal of Obstetrics and Gynaecology, the British Medical Journal, Clinical Chemistry, the European Journal of Obstetrics and Gynaecology, the Journal of Perinatal Medicine and Reproductive Sciences and research funding bodies such as the Medical Research Council (UK), the Wellcome Trust, Action Research, the British Heart Foundation, Wellbeing and Sparks, the Children’s Medical Research Charity.

Selected Recent Publications


McCarthy FP, Khashan AS, Quigley E, Shanahan F, Oʼ Regan P, Cronin C, Kenny L. Undiagnosed Maternal Celiac Disease in Pregnancy and an Increased Risk of Fetal Growth Restriction. J Clin Gastroenterol. 2009 Jun 24. [Epub ahead of print]

Walsh SK, English FA, Johns EJ, Kenny LC. Plasma-mediated vascular dysfunction in the reduced uterine perfusion pressure model of preeclampsia: a microvascular characterization. Hypertension. 2009 Aug;54(2):345-51.

Khashan AS, McNamee R, Abel KM, Mortensen PB, Kenny LC, Pedersen MG, Webb RT, Baker PN. Rates of preterm birth following antenatal maternal exposure to severe life events: a population-based cohort study. Hum Reprod. 2009 Feb;24(2):429-37.

Khashan AS, McNamee R, Abel KM, Pedersen MG, Webb RT, Kenny LC, Mortensen PB, Baker PN. Reduced infant birthweight consequent upon maternal exposure to severe life events. Psychosom Med. 2008 Jul;70(6):688-94.

Kenny LC, Broadhurst D, Brown M, Dunn WB, Redman CW, Kell DB, Baker PN. Detection and identification of novel metabolomic biomarkers in preeclampsia. Reprod Sci. 2008 Jul;15(6):591-7.

Dunn WB, Broadhurst D, Brown M, Baker PN, Redman CW, Kenny LC, Kell DB. Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Aug 15;871(2):288-98.

Khashan AS, Abel KM, McNamee R, Pedersen MG, Webb RT, Baker PN, Kenny LC, Mortensen PB. Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events. Arch Gen Psychiatry. 2008 Feb;65(2):146-52.

Selected Book Chapters and Reviews


Ismail SK, Kenny L. Review on hyperemesis gravidarum. Best Pract Res Clin Gastroenterol. 2007;21(5):755-69.

Horgan RP, Kenny LC. Management of teenage pregnancy. The Obstetrician & Gynaecologist 2007;9:153–158.

Smith RS, Kenny LC. Current thoughts on the pathogenesis of pre-eclampsia. The Obstetrician & Gynaecologist 2006;8:7-13

LM Byrd, LC Kenny, PN Baker. Chapter 26, Hypertension, preeclampsia and IUGR in Women’s Vascular Health, Eds Greer, Ginsberg and Forbes, Hodder Arnold, London 2006

LC Kenny. Contraception and Termination in Obstetrics and Gynaecology, An Evidence based Text for the MRCOG, Eds Baker and Lusley, Hodder Arnold, London 2004

Gillham JC, Kenny LC, Baker PN. An overview of endothelium-derived hyperpolarising factor (EDHF) in normal and compromised pregnancies. Eur J Obstet Gynecol Reprod Biol. 2003 Jul 1;109(1):2-7.

LC Kenny, PN Baker. Trophoblast Invasion in Preeclampsia, Etiology and Management, Eds Baker and Kingdom, Parthenon Publishing, New York, 2003

LC Kenny, PN Baker. The Etiology of Preeclampsia in Hypertension in Pregnancy, Eds Belfort, Thornton and Slade, Marcel Dekker Inc, New York, 2002

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