Peer-reviewed Original Research Journal Articles

2015

Roba, K.T., O’Connor, T.P., Belachew, T. and O’Brien, N.M. (2015) Seasonal variation in nutritional status and anaemia among lactating mothers in two agro-ecological zones of Rural Ethiopia: Longitudinal study design.  Journal of Nutrition (in preparation).  

Roba, K.T., O’Connor, T.P., Belachew, T. and O’Brien, N.M. (2015) Stunting and anemia among children 6-23 months of age in two agro-ecological zones of Rural Ethiopia.  Nutrition Research (submitted)  

Valcarcel, J., Reilly, K., Gaffney, M. and O’Brien, N.M. (2015). Levels of potential bioactive compounds including carotenoids, vitamin C and phenolic compounds, and expression of their cognate biosynthetic genes vary significantly in different varieties of potato (Solanum tuberosum L.) grown under uniform cultural conditions. Journal of the Science of Food and Agriculture (submitted) 

O’Keeffe, R., Kenny,O., Brunton,N.P.,  Hossain,M.P.,  Rai,D.K.,  Jones,P.W., O’Brien,N.M., Maguire, A.R. and Collins, S.G. (2015). Synthesis of novel 24-aminochol-8-enes derived from lanosterol: Cytotoxic and apoptotic potential in U937 Cells.  Bioorganic & Medicinal Chemistry (submitted) 

Sae-leaw, T., Benjakul, S. and O’Brien, N.M. (2015) Effect of pre-treatments and drying methods on properties and fishy odour of gelatin from seabass (Latescalcarifer) skin. Drying Technology (submitted)  

Sae-leaw, T., Benjakul, S. and O’Brien, N.M. (2015)Effect of pre-treatments and defatting processes of seabass (Lates calcarifer) skin on properties and fishy odour of gelatin. Process Biochemistry (submitted) 

Nury, T., Zarrouk, A., Samadi, M., Durand, P., Doria, M.., Riedinger, M., Limagne, E., Mackrill, J., Vejus, A., Delmas, D., Prost, M., Moreau, T., Hammami, M., Delage-Mourroux, R., O’Brien, N.M. Lizard, G. (2015).  Evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) on 7-ketocholesterol-, 7β-hydroxycholesterol-, and 24(S)-hydroxycholesterol-treated 158N murine oligodendrocytes: attenuation of oxysterol-induced oxiapoptophagy and enhancement of α-tocopherol protective effects. Steroids (submitted)

Valcarcel, J., Reilly, K., Gaffney, M. and O’Brien, N.M. (2015). Total carotenoids and ascorbic acid content in sixty varieties of potato (Solanum tuberosum L.) grown in Ireland. Potato Research (in press).

2014

McCarthy, A.L., O’Callaghan, Y.C., Connolly, A., Piggott, C.O., FitzGerald, R.J. and O’Brien, N.M. (2014). A study of the ability of bioactive extracts from brewers' spent grain to enhance the antioxidant and immunomodulatory potential of food formulations following in vitro digestion. International Journal of Food Science and Nutrition (in press) 

McCarthy, M., O’Halloran, J., O’Brien, N.N. and van Pelt, F.N.A.M. (2014).  Does the marine biotoxin okadaic acid cause DNA fragmentation in the blue mussel and the pacific oyster? Marine Environmental Research (in press) doi: 10.1016/j.marenvres.2014.09.009

O’Callaghan, Y.C., Smyth, T.J., Brunton, N. and O’Brien, N.M. (2014) Anti-inflammatory effects of extracts prepared from wild Irish mushrooms in RAW264.7 mouse macrophage cells. Journal of Medicinal Foods (in press)doi: 10.1089/jmf.2014.0012

O’Sullivan, A.M., O’Callaghan, Y.C., O’Grady, N.M., Waldron, D., Smyth, T., O’Brien, N.M. and Kerry, JP. (2014). An examination of the potential of seaweed extracts as functional ingredients in milk. International Journal of Dairy Technology 67, 182-193.

McCarthy, A.L., O’Callaghan, Y.C., Connolly, A., Piggott, C.O., FitzGerald, R.J. and O’Brien, N.M. (2014).  Phenolic-enriched fractions from brewers’ spent grain possess cellular antioxidant and immunomodulatory effects in cell culture model systems Journal of the Science of Food and Agriculture 94, 1373-1379.

Valcarcel, J., Reilly, K., Gaffney, M. and O’Brien, N.M. (2014). Effect of genotype and environment on the glycoalkaloid content of rare, heritage and commercial potato varieties.  Journal of Food Science 79, 1039-1048

Kehoe, J.J., Liskova, K., Mok, K.H., O’Brien, N.M., Kelly, A.L. and Brodkorb, A. (2014).  Formation of cytotoxic α-Lactalbumin / sodium oleate complexes: concentration andtemperature effects. International Dairy Journal 38, 65-73

 

2013

McCarthy, A.L., O’Callaghan, Y.C., Connolly, A., Piggott, C.O., FitzGerald, R.J. and O’Brien, N.M. (2013).  In vitro antioxidant and anti-inflammatory effects of brewers’ spent grain protein rich isolate and its associated hydrolysates.  Food Research International 50, 205-212.

O’Callaghan, Y.C., Kenny, O., O’Connell, N.M., Maguire, A.R., McCarthy, F.O. and O’Brien, N.M. (2013).  Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in the U937 and HepG2 cell lines. Biochimine 95, 496-503.

Silva, F.G.D., O’Callaghan, Y.C., O’Brien, N.M. and Netto, F.M. (2013) Antioxidant activity of flaxseed products: the effect of in vitro digestion.   Plant Foods for Human Nutrition68, 24-30.

Loizzo, M.R., Pugliese, A., Bonesi, M., De Luca, D., O’Brien, N.M., Menichini, F. and Tundis, R. (2013)Influence of drying and cooking process on the phytochemical content, antioxidant and hypoglycaemic properties of two bell Capsicum annum L. cultivars. Food and Chemical Toxicology53, 392-401.

O’Sullivan, A.M., O’Callaghan, Y.C., O’Grady, N.M., Hayes, M., Kerry, J.P. and O’Brien, N.M. (2013).  Use of a Caco-2 cell model to assess the antioxidant activity of Irish brown seaweed extracts manufactured using accelerated solvent extraction (ASE®).  Journal of Functional Foods 5, 940-948.

Kenny, O., Brunton, N., Houssain, M., Rai, D., Collins, S.G., Maguire, A.R., Jones, P. and O’Brien, N.M (2013).  Anti-inflammatory properties of potato glycoalkaloids in stimulated Jurkat and Raw 264.7 macrophages.  Life Sciences 92, 775-782.

O’Sullivan, A.M., O’Callaghan, Y.C., O’Connor, T.P. and O’Brien, N.M. (2013).   Comparison of the antioxidant activity of commercial honeys, before and after in-vitro digestion. Polish Journal of Food and Nutrition Sciences 63, 167-171

Kyriakoudi, A., Tsimidou, M.S., O’Callaghan, Y.C., Galvin, K. and O’Brien, N.M. (2013).  Changes in total and individual crocetin esters upon in vitro gastrointestinal digestion of saffron aqueous extracts.  Journal of Agricultural and Food Chemistry61, 5318-5327

McCarthy, A.L., O’Callaghan, Y.C., Neugart, S., Connolly, A., Piggott, C.O., Jansen, M., Krumbein, A., Schreiner, M., FitzGerald, R.J. and O’Brien, N.M. (2013).  The hydroxycinnamic acid content of barley and brewers’ spent grain (BSG) and the potential to incorporate phenolic extracts of BSG as antioxidants into fruit beverages.  Food Chemistry 141, 2567-2574.

Pugliese, A., Loizzo, M.R., Tundis, R., O’Callaghan, Y., Galvin, K., Menichini, F. and O’Brien, N.M. (2013).The effect of domestic processing on the content and bioaccessibility of carotenoids from chili peppers (Capsicum species). Food Chemistry 141, 2606-2613.

Kenny, O., Brunton, N., Rai, D., Collins, S.G., Maguire, A.R., Jones, P. and O’Brien, N.M (2013) Assessment of the cytotoxic and apoptotic potential of potato glycoalkaloids in a number of cancer cell lines.  Journal of Agricultural Science and Applications 2, 184-192.

O’Callaghan, Y.C., Drummond, E., O’Gorman, D.M. and O’Brien, N.M. (2013).  Antioxidant and pro-apoptotic effects of marine-derived multi-mineral Aquamin supplemented with green tea extract, Sunphenon and pine bark extract, Enzogenol. Journal of Medicinal Foods16, 920-926.

O’Sullivan, D., Lahart, N., O’Callaghan, Y.O., O’Brien, N.M. and FitzGerald, R.J. (2013).  Characterisation of the physicochemical, residual antigenicity and cell activity properties of transglutaminase cross-linked sodium caseinate hydrolysates.  International Dairy Journal 33, 49-54.

Pugliese, A.,O’Callaghan, Y.C., Tundis, R., Galvin, K., Menichini, F., O’Brien, N.M. and Loizzo, M.R., (2013).  In vitro investigation of the bioaccessibility of carotenoids from raw, frozen and boiled red chili peppers (Capsicum annuum).  European Journal of Nutrition(Open Access).

McCarthy, A.L., O’Callaghan, Y.C., Connolly, A., Piggott, C.O., FitzGerald, R.J. and O’Brien, N.M. (2013).  Brewers' spent grain (BSG) protein hydrolysates decrease hydrogen peroxide (H2O2)-induced oxidative stress and concanavalin-A (con-A) stimulated IFN-g production in cell culture.Food & Function 4, 1709 – 1716.

 

2012

McCarthy, A.L., O’Callaghan, Y.C., Connolly, A., Piggott, C.O., FitzGerald, R.J. and O’Brien, N.M. (2012).  Phenolic extracts of Brewers' Spent Grain (BSG) as functional ingredients - assessment of their DNA protective effect against oxidant-induced DNA single strand breaks in U937 cells.  Food Chemistry134, 641–646.

O’Sullivan, A.M., O’Callaghan, Y.C., O’Grady, N.M., Queguineur, B., Hanniffy, D. Kerry, J. and O’Brien, N.M. (2012). Assessment of the ability of seaweed extracts to protect against hydrogen peroxide and tert-butyl hydroperoxide induced cellular damage in Caco-2 cells.  Food Chemistry 134, 1137–1140.

O’Connell, N.M., O’Callaghan, Y.C., O’Brien, N.M., Maguire, A.R. and McCarthy, F.O. (2012). Synthetic routes to campesterol and dihydrobrassicasterol: A first reported synthesis of the key phytosterol dihydrobrassicasterol  Tetrahedron  68, 4995-5004

Kenny, O., O’Callaghan, Y.C., O’Connell, N.M., McCarthy, F.O., Maguire, A.R. and O’Brien, N.M. (2012).  Oxidised derivatives of dihydrobrassicasterol:  Cytotoxic and apoptotic potential in U937 and HepG2 cells.  Journal of Agricultural and Food Chemistry 60, 5952-5961.

 

2011

O’Sullivan, A.M., O’Callaghan, Y.C., O’Grady, M.N., Queguineur, B., Hanniffy, D.,Troy, D.J., Kerry, J.P. and O’Brien, M.N. (2011).  In vitro and cellular antioxidant activities of seaweed extracts prepared from five brown seaweeds harvested in spring from the west coast of Ireland.  Food Chemistry 126, 1064–1070.

Lahart, N., O’Callaghan, Y.C., Aherne S.A., O’Sullivan, D., Fitzgerald, R. and O’Brien N.M. (2011).  Extent of hydrolysis effects on casein hydrolysate bioactivity: evaluation using the human Jurkat T cell line. International Dairy Journal21, 777-782.

Lišková, K., Auty, M. A. E., Chaurin, V., Min, S., Mok, K. H., O'Brien, N., Kelly, A. L., and Brodkorb, A. (2011). Cytotoxic complexes of sodium oleate with β-lactoglobulin. European Journal of Lipid Science and Technology, 113, 1207-1218. 

2010

Foley, D.A., O’Callaghan, Y.C., O’Brien, N.M., McCarthy, F.O. and Maguire, A.R. (2010) Synthesis and characterisation of stigmasterol oxidation products.  Journal of Agricultural and Food Chemistry 58, 1165-1173. 

Liskova, K., Kelly, A.L., O’Brien, N.M. and Brodkorb, A. (2010) Effect of denaturation of alpha-lactalbumin on the formation of BAMLET (Bovine alpha-Lactalbumin Made Lethal to Tumor Cells)’. Food Chemistry58, 4421-4427

Daly, T., Ryan, E., Aherne, S.A., O’Grady, M.N.,  Hayes, J.E.,  Allen, P., Kerry, J.P. and O’Brien,N.M. (2010) Bioactivity of ellagic acid-, lutein- or sesamol-enriched pork and beef patties assessed using an in vitro digestion and Caco-2 cell model system.  Food Research International43, 753-760.

Phelan, M., Aherne S.A., O’Sullivan, D., Fitzgerald, R. and O’Brien N.M. (2010).  Growth inhibitory effects of casein hydrolysates on cancer cells.  Journal of Dairy Research 77, 176-182.

O’Sullivan, L., Galvin, K., Aherne S.A. and O’Brien, N.M. (2010).  Effects of cooking on the profile and micellarisation of 9-cis, 13-cis and all-trans-b-carotene in green vegetables.  Food Research International43, 1130-1135.

O’Sullivan, L., Jiwan, M., Daly, T., O’Brien, N.M. and Aherne S.A. (2010). Bioaccessiblity, uptake and transport of carotenoids from peppers (Capsicum spp) using the coupled in vitro digestion and human intestinal Caco-2 cell model.  Journal of Agricultural and Food Chemistry 12, 5374-5379.

Daly, T., Jiwan, MA, O’Brien, N.M. and Aherne, S.A. (2010).  Carotenoid content of commonly consumed herbs and assessment of their bioaccessibility using an in vitro digestion model.  Plant Foods for Human Nutrition 65, 164-169.

Lišková, K., Kelly, A.L., O'Brian, N.M., & Brodkorb, A. (2010). Effect of α-lactalbumin denaturation on its potential anti-cancer properties. Journal of Agricultural and Food Chemistry, 58, 4421-4427.

Jiwan, M.A., Duane, P., O’Sullivan, L., O’Brien, N.M., Aherne-Bruce, S.A. (2010) Carotenoid bioaccessibility from commercially available organic and non-organic baby food products.  Journal of Food Composition and Analysis23, 346-352.

O’Callaghan, Y.C., Foley, D., O’Connell, N.M., McCarthy, F.O., Maguire, A.R. and O’Brien, N.M. (2010).  The cytotoxic and apoptotic effects of the oxidised derivatives of stigmasterol in the U937, human monocytic cell line. Journal of Agricultural and Food Chemistry 58, 10793-10798. 

Aherne, S.A, Daly, T., Jiwan, M.A., O’Sullivan, L. and O’Brien, N.M. (2010).  Bioavailability of beta-carotene isomers from raw and cooked carrots using an in vitro digestion model coupled with a human intestinal Caco-2 cell model.  Food Research International43, 1449–1454.

O’Callaghan, Y.C. and O’Brien, N.M. (2010).  Bioaccessibility cellular uptake and transepithelial transport of a-tocopherol and retinol from a range of supplemented foodstuffs assessed using the caco-2 cell model.  International Journal of Food Science and Technology45, 1436-1442.  

2009

Kilmeade, M.E., Hartl, M.G.J., O’Halloran, O’Brien, N.M. J. Sheehan, D., Mothersill, C. and van Pelt, F.N.A.M. (2009).  Effects of contaminated sediment from Cork Harbour, Ireland on the cytochrome P450 system of turbot. Ecotoxicology and Environmental Safety72, 747-755.

Phelan, M., Aherne S.A., O’Sullivan, D., Fitzgerald, R. and O’Brien N.M. (2009).  Potential bioactive effects of novel casein hydrolysates on human cultured cells.  International Dairy Journal19, 279-285.

Ryan, E., Aherne, S.A., O’Grady, M.N., McGovern, L., Kerry, J.P and O’Brien, N.M. (2009).  Bioactivity of herb-enriched beef patties.  Journal of Medicinal Foods12, 893-901.

Lordan, S., O’Brien, N.M. and Mackrill, J.J. (2009).  The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide.  Journal ofBiochemical and Molecular Toxicology23, 324-332.

Phelan, M., Aherne, S.A. and O’Brien (2009)Bioactive effects of wood knot extracts on cultured human cells.  Journal of Medicinal Foods12, 1245-1251.

Daly, T., Aherne-Bruce, A.S, O’Connor, T.P. and O’Brien, N.M. (2009).  Lack of genoprotective effects of phytosterols and conjugated linoleic acids on caco-2 cells.  Food and Chemical Toxicology47, 1791-1796

Hayes, J.E., Stepanyan, V., Allen, P., O’Grady, M.N., O’Brien, N.M. and Kerry, J.P. (2009).  The effect of lutein, sesamol, ellagic acid and olive leaf extract on lipid oxidation and oxymyoglobin oxidation in bovine and porcine muscle model systems.  Meat Science83, 201-208.

Coughlan, B.M., Moroney, G.A., van Pelt, F.N.A.M., O’Brien,N.M., Davenport, J., O’Halloran, J. (2009).  The effect of salinity on the Manila Clam (Ruditapes philippinarum) using the neutral red retention assay with adapted physiological saline solutions.  Marine Pollution Bulletin 11, 1680-1684.

Aherne, S.A., Jiwan, M.A., Daly, T. and O’Brien, N.M. (2009).  Geographical location has greater impact on carotenoid content and bioaccessibility from tomatoes than variety.  Plant Foods for Human Nutrition64, 250-256

O’Sullivan, L., Aherne S.A. and O’Brien, N.M. (2009).  Investigation of beta-carotene and lutein transport in Caco-2 cells: carotenoid-carotenoid interactions and transport inhibition by ezetimibe.International Journal of Vitamin and Nutrition Research79, 337-347. 

2008

O’Grady, M.N., Carpenter, R., Lynch, P.B., O’Brien, N.M. and Kerry, J.P. (2008).  Addition of grape seed extract and bearberry to porcine diets: Influence on quality attributes of raw and cooked pork.  Meat Science 78, 438-446.

Lordan, S.A.,O’Neill, C. and O’Brien, N.M. (2008).  Effects of apigenin, lycopene and astaxanthin on 7b-hydroxycholesterol-induced apoptosis and Akt phosphorylation in U937 cells.  British Journal of Nutrition 11, 1-10.

Kenny, O., O’Callaghan, Y.C. and O’Brien, N.M. (2008).  Effects of  ingredient incorporation into sausage meat on the micellarisation and uptake of a-tocopherol by Caco-2 human intestinal cells.  Food Science and Technology International14, 79-86.

Aherne, S.A. and O’Brien, N.M (2008).  Modulation of cytokine production by plant sterols in stimulated human Jurkat T cells.  Molecular Nutrition and Food Research52, 664-673.

Jansen, M.A.K., Hectors, K., O’Brien, N.M., Guisez, Y. and Potters, G.  (2008). Plant stress and human health; do human consumers benefit from UV-B acclimated crops?  Plant Science175, 449-458.

Lordan, S.A.,Mackrill, J. and O’Brien, N.M. (2008).  Involvement of Fas signalling in 7b-hydroxycholesterol and cholesterol-5b,6b-epoxide-induced apoptosis.  International Journal of Toxicology27, 279-285.

Ryan, L., O’Connell, O., O’Sullivan, L., Aherne, S.A. and O’Brien, N.M. (2008).  Micellarisation of carotenoids from raw and cooked vegetables.  Plant Foods for Human Nutrition 63, 127-133.

O’Sullivan, L., Ryan L., Aherne, A.S. and O’Brien, N.M. (2008).  Cellular transport of lutein is greater from uncooked rather than cooked spinach irrespective of whether it is fresh, frozen or canned.  Nutrition Research 28, 532-538.

O’Connell, O., Ryan, L., O’Sullivan, L., Aherne-Bruce, S.A. and O’Brien, N.M. (2008) Carotenoid micellarization varies greatly between individual and mixed vegetables with or without the addition of fat or fibre.  International Journal of Vitamin and Nutrition Research78, 238-246. 

2007

Aherne, S.A., Kerry, J.P. and O’Brien, N.M. (2007).  Effect of plant extracts on antioxidant status and oxidant-induced stress in Caco-2 cells.  British Journal of Nutrition97, 321-328.

O’Connell, O.F., Ryan L. and O’Brien, N.M. (2007).  Xanthophyll carotenoids are more bioaccessible from fruits than dark green vegetables.  Nutrition Research27, 258-264.

O’Sullivan, L., Ryan, L. and O’Brien, N.M. (2007).  Comparison of the uptake and secretion of carotene and xanthophyll carotenoids by Caco-2 intestinal cells.  British Journal of Nutrition98, 38-44.

Carpenter, R., O’Grady, M.N., O’Callaghan, Y.C., O’Brien, N.M. and Kerry, J.P. (2007).  Evaluation of the antioxidant potentialof grape seed and bearberry extracts in raw and cooked pork   Meat Science76, 604-610.

Hartl, M.G.J., Kilmeade, M.E., Sheehan, D., Mothersill, C., O’Halloran, J., O’Brien, N.M. and van Pelt, F. (2007).  Hepatic biomarkers of sediment-associated pollution in juvenile turbot, Scophthalmus maximus L.  Marine Environmental Research64, 191-208.

Daly, T., Galvin, K., Aherne, A., O’Connor, T.P. and O’Brien, N.M. (2007).  Phytosterol and tocopherol content in commercially available sterol-enriched and non-enriched dairy spreads.  Proceedings of the 36th Research Conference- Food, Nutrition and Consumer Sciences 2, 47-49.

Ryan, E., Galvin, K., O’Connor, T.P., Maguire, A.R. and O’Brien, N.M. (2007) Phytosterol, tocopherol, and squalene content and fatty acid profile of selected seeds, grains, and legumes.  Plant Foods for Human Nutrition 62, 85-91.

Lordan, S., O’Callaghan, Y.C. and O’Brien, N.M. (2007).  Death signalling pathways in human myeloid cells by oxLDL and its cytotoxic components 7b-hydroxycholesterol and cholesterol-5b,6b-epoxide.  Journal of Biochemical and Molecular Toxicology21, 362-372.

Daly, T., Aherne, A., O’Connor, T.P. and O’Brien, N.M. (2007).  The effects of conjugated linoleic acid on the viability and proliferation of caco-2 cells.  Proceedings of the 37th Research Conference- Food, Nutrition and Consumer Sciences 3, 23-24.

Phelan, M., Aherne, S.A., O’Brien, N.M., O’Sullivan, D. and Fitzgerald, R.J. (2007).  Viability, growth and glutathione content of human Jurkat cells supplemented with casein hydrolysates.  Proceedings of the 37th Research Conference- Food, Nutrition and Consumer Sciences 3, 90-91. (ISBN)

McGovern, L., O’Grady, M.N., Aherne, S.A., Ryan, E., O’Brien, N.M. and Kerry, J.P. (2007). The effect of plant extracts on lipid oxidation and oxymyoglobin oxidation in beef muscle model systems.  Proceedings of the 53rd International Congress of Meat Science and TechnologyBeijing, China, 227–228.  (ISBN)

McGovern, L., O’Grady, M.N., Ryan, E., O’Brien, N.M. and Kerry, J.P. (2007).  The effect of plant extracts on colour and lipid oxidation in raw and cooked beef patties stored in modified atmosphere packs. Proceedings of the 53rd International Congress of Meat Science and TechnologyBeijing, China, 227–228.  (ISBN)  

2006

Hartl, M.G.J., Kilemade, M., Coughlan, B.M., O’Halloran, J., van Pelt, F., Sheehan, D., Mothersill, C. and O’Brien, N.M. (2006).  A two-species biomarker model for the assessment of sediment toxicity in the marine and estuarine environment using the Comet assay.  Journal of Environmental Science and Health 41, 939-953.

Ryan, L., O’Callaghan, Y.C. and O’Brien, N.M. (2006).  Involvement of calcium in 7b-hydroxycholesterol and cholesterol-5b,6b-epoxide-induced apoptosis.  International Journal of Toxicology25, 35-39.

Carpenter, R., O’Callaghan, Y.C., O’Grady, M.N. O’Brien, N.M. and Kerry J.P. (2006). Antioxidant effects of health promoting plant derived neutraceuticals for use in meat systems.  Proceedings of the 35th Research Conference – Food, Nutrition and Consumer Sciences1, 5-7.

Carpenter, R., O’Callaghan, Y.C., O’Grady, M., Kerry J. and O’Brien, N.M. (2006).  Modulatory effects of resveratol, citroflavan-3-ol and plant derived extracts on oxidative stress in U937 cells.  Journal of Medicinal Food 9, 187-195.

Ryan, E., Galvin, K., O’Connor, T.P. Maguire, A.R. and O’Brien, N.M. (2006).  Phytosterol, tocopherol and squalene content of brazil, pecan, pine, pistachio and cashew nuts.  International Journal of Food Sciences and Nutrition57, 219-28.

Dowling, V., McDonagh, B., Cotter, E.M., O’Brien, N.M., van Pelt, F., O’Halloran, J. and Sheehan, D. (2006).  Two-dimensional electrophoresis analysis of glutathione affinity-selected proteins from the clam Tapes semidecussatus:  Evidence for tissue-specific expression of redox proteins.  Comparative Biochemistry and Physiology Part D: Genomics and Proteomics1, 267-272. 

2005

Davoren, M., Ní Shúilleabháin, S., Hartl, M.G.J., Sheehan, D., O’Brien, N.M., O’Halloran, J., Van Pelt, F. and Mothersill, C. (2005).  Assessing the potential of fish cell lines as tools for the cytotoxicity testing of estuarine sediment elutriates.  Toxicology in Vitro19, 421-431. 

Ní Shúilleabháin, S., Davoren, M., Mothersill, C., Sheehan, D., Hartl, M., Kilemade, M., O’Brien, N.M., Van Pelt, F., O’Halloran, J. and Lyng, F. (2005).  Identification of a multixenobiotic resistance mechanism in primary cultured epidermal cells from Oncorhynchus mykiss and the effects of environmental complex mixtures on its activity.  Aquatic Toxicology73, 115-127.

O’Sullivan A., O’Callaghan, Y.C. and O’Brien, N.M. (2005).  Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial BAR cells and human monocytic U937 cells.  International Journal of Toxicology24, 173-179.

Davoren, M., Ní Shúilleabháin, S., Hartl, M., Sheehan, D., O’Brien, N.M., O’Halloran, J., Van Pelt, F. and Mothersill, C. (2005).  A test battery approach for the ecotoxicological evaluation of estuarine sediments.  Ecotoxicology14, 741-755.

Ryan, E., Chopra, J., McCarthy, F., Maguire, A.R. and O’Brien, N.M. (2005).  Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products.  British Journal of Nutrition94, 443-451.

McCarthy, F.O., Chopra, J., Ford, A., Hogan, S., Kerry, J., O’Brien, N.M., Ryan, E. and Maguire, A.R. (2005).  Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives.  Organic and Biomolecular Chemistry3, 3059-3065.

Ryan, L., O’Callaghan, Y.C. and O’Brien, N.M. (2005).  The role of the mitochondria in apoptosis induced by 7b-hydroxycholesterol and cholesterol-5b,6b-epoxide.  British Journal of Nutrition94, 519-525.

Ní Shúilleabháin, S., Mothersill, C., Sheehan, D., O’Brien, N.M., O’Halloran, J., Van Pelt, F., Kilemade, M. and Davoren, M. (2005).   Cellular responses in primary epidermal cultures from rainbow trout exposed to zinc chloride.  Ecotoxicology and Environmental Safety.  DOI: 10.1016/j.ecoenv.2005.08.004 (10 pages).

Dowling, V., Hoarau, P.C., Romeo, M., O’Halloran, J., van Pelt, F., O’Brien, N.M. and Sheehan, D. (2005).  Protein carbonylation and heat shock response inRuditapes decussatusfollowing p,p′-dichlorodiphenyldichloroethylene (DDE) exposure: a proteomic approach reveals that DDE causes oxidative stress.  Aquatic Toxicology77, 11-18.

 

 

Peer-reviewed Review Articles

Zarrouk, A., Vejux, A., Mackrill, J., O’Callaghan, Y.C., Hammami, M., O’Brien, N.M. and Lizard, G (2014). Involvement of oxysterols in age related diseases and ageing processes. Aging Reviews (in press).

O’Callaghan, Y.C., McCarthy, F.O. and O’Brien, N.M. (2014).  Recent advances in phytosterol oxidation products.  Biochemical and Biophysical Research Communications466, 786-791.

McCarthy, A.L., O’Callaghan, Y.C., Piggott, C.O., FitzGerald, R.J. and O’Brien, N.M. (2013).  Brewers’ spent grain; bioactivity of phenolic component, its role in animal nutrition and potential for incorporation in functional foods: a review. Proceedings of the Nutrition Society 72, 117–125.

McCarthy, A.L., O’Callaghan, Y.C. and O’Brien, N.M. (2013).  Protein hydrolysates from agricultural crops – bioactivity and potential for functional food development.  Agriculture3, 112-130.

McCarthy, A.L. and O’Brien, N.M. (2013).  Bioaccessibility of functional ingredients. Current Nutrition and Food Science9, 271-282. 

Schreiner, M., Mewis, I., Huyskens-Keil, S., Jansen, M.A.K., Zrenner, R., Winkler, J.B., O’Brien, N.M. and  Krumbein, A. (2012).  UV-B induced secondary plant metabolites - potential benefits for plant and human health.  Critical Reviews in Plant Sciences3l, 229-240.

Milner, S.E., Brunton, N.P., Jones, P.W., O’Brien, N.M., Collins, S.G. and Maguire, A.R. (2011).   Bioactivities of glycoalkaloids and their aglycones from solanum species.  Journal of Agricultural and Food Chemistry 59, 3454-3484.

Phelan, M., Aherne S.A., FitzGerald, R. and O’Brien N.M. (2009).  Casein-derived bioactive peptides: Absorption, metabolism, and biological effects.  International Dairy Journal19, 643-654.

Ryan, E. McCarthy, F., Maguire, A. and O’Brien, N.M. (2009).  Phytosterol oxidation products:  their formation, occurrence and biological effects.  Food Reviews International 25, 157-174.

Lordan, S., Mackrill, J.J. and O’Brien, N.M. (2009).  Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases.  Journal of Nutritional Biochemistry20, 321-336.

Ryan, L., O’Callaghan, Y.C. and O’Brien, N.M. (2005).  Oxidised products of cholesterol: Their role in apoptosis.  Current Nutrition and Food Sciences1, 41-51.

O’Brien, N.M. and O’Connor, T.P. (2004). The importance of nutrition and diet in cancer prevention.  Journal of Community Nursing 18, 10-14.

O’Brien, N.M. (2004).  Potential uses and benefits of plant sterols (phytosterols and phytostanols): future directions.  RELAY e-Newsletter, November 2004.

O’Brien, N.M. and O’Connor T.P. (2003).  Diet, nutrition and cancer prevention.  Nutrition in Practice.  Quarterly bulletin published by Sugar Bureau UK.4, 1-4.

O’Brien, N.M. and O’Connor T.P. (2002).  Nutrition and cancer.  Cancer Nursing Practice1, 31-36.  

Aherne, S.A. and O’Brien N.M. (2001).  Dietary flavonols: chemistry, food content and metabolism.  Nutrition – The International Journal of Applied and Basic Nutritional Sciences18, 17-23. 

O’Brien, N.M. (2001).  Nutrition and health.  Irish Scientist Yearbook9, 206.

Morrissey, P.A. and O’Brien, N.M. (1998).  Dietary antioxidants in health and disease.  International Dairy Journal 8, 463-472. 

Fox, P.F., O'Connor, T.P., Guinee, T., McSweeney, P. and O'Brien, N.M. (1996).  Cheese: physical, chemical and nutritional aspects.  Advances in Food and Nutrition Research39, 163-328.

O'Connor, T.P. and O'Brien, N.M. (1994).  Education for a lifetime of learning.  Technology Ireland26, 20-21.

O'Brien, N.M. and O'Connor, T.P. (1993).  Milk, cheese and dental caries.  International Journal of Dairy Technology46, 46-49. 

 

Book Chapters

O’Callaghan, Y.C., O’Connor, T.P. and O’Brien, N.M. (2014) Nutritional aspects of cheese.  In: Fundamentals of Cheese Science.  P.F. Fox, T.P Guinee and P.L.H. McSweeney, authors.  Aspen Publication, Maryland, USA.  In press.

McCarthy, A., O’Connor, T.P. and O’Brien, N.M. (2013).  Cheese in the context of diet and nutrition. In: Handbook of Cheese in Health: Production, Nutrition and Medical Sciences. Victor R. Preedy, Ronald Ross Watson and Vinood B. Patel, Editors.  Wageningen Academic Publishers. ISBN: 978-90-8686-211-5. Pages 15-26.

O’Brien, N.M. and O’Connor, T.P. (2011).   Milk Lipids: Lipid Oxidation.  In: Encyclopedia of Dairy Science, 2nd Edition. J.W. Fuquay, P.F. Fox and P.L.H. McSweeney Editors.  Elsevier Publishers, London.  Pages 716-720.

O’Brien, N.M. and O’Connor, T.P. (2011).  Milk Lipids: Nutritional significance.  In: Encyclopedia of Dairy Science, 2nd edition.  J.W. Fuquay, P.F. Fox and P.L.H. McSweeney Editors.  Elsevier Publishers, London. Pages 711-715.

O’Connor, T.P. and O’Brien, N.M. (2011).  Butter and Other Milk Fat Products: Fat Replacers.  In: Encyclopedia of Dairy Science, 2nd Edition. J.W. Fuquay, P.F. Fox and P.L.H. McSweeney Editors.  Elsevier Publishers, London. Pages 528-532.

O’Brien, N.M. and O’Connor T.P. (2007).  Brief outlines on the significance of the following in cheese: 1. biogenic amines (p. 148-149); 2. mycotoxins (p. 150-151); 3. vitamins (p. 153-154); 4. dental caries (p.155-156) ;  In: Cheese Problems Solved.  P.L.H. McSweeney editor.  Woodhouse Publishing Limited, Cambridge, UK.

O’Connor, T.P. and O’Brien, N.M. (2006).  Lipid oxidation in milk and milk products.  In: Advanced Dairy Chemistry, Volume 2.  Third Edition.  P.F. Fox, P.L.H. McSweeney editors.  Springer, New York.  Pages 557-600.

O’Brien, N.M. and O’Connor, T.P. (2004).  Nutritional aspects of cheese.  In: Cheese, Chemistry, Physics and Microbiology, 3rd Edition.  P.F. Fox, P.L.H. McSweeney, T.M. Cogan and T.P. Guinee, Editors.  Elsevier Publishers, London.  Pages 573-581.

O’Brien, N.M., O’Connor, T.P., O’Callaghan, J. and Dobson, A. (2004).  Toxins in cheese.  In: Cheese, Chemistry, Physics and Microbiology, 3rd Edition.  P.F. Fox, P.L.H. McSweeney, T.M. Cogan and T.P. Guinee, Editors.  Elsevier Publishers, London.  Pages 561-571.

O’Brien, N.M. and O’Connor, T.P. (2004).  Carotenoids effects on cellular processes: Induction of Phase I and Phase II enzymes.  In: Carotenoids in Health and Disease.  N.I. Krinsky, S.T. Mayne and H. Sies, Editors.  Marcel Dekker, Inc., New York.  Pages 197-208.

Kerry, J., Gilroy, D. and O’Brien, N.M. (2002).  Formation and content of cholesterol oxidation products in meat and meat products.  In: Sterol Oxidation Products in Foods and Biological Samples: Analysis, Content and Biological Effects.  F. Guardiola, P.C. Dutta, R. Codony and G.P. Savage, Editors.  AOCS Press, IL, USA.  Pages 162-185.

O’Brien, N.M. and O’Connor, T.P. (2002).  Lipids: Oxidation.  In: Encyclopedia of Dairy Sciences.  H. Roginski, J.W. Fuquay and P.F. Fox, Editors.  Academic Press, London.  Pages 1600-1604.

O’Brien, N.M. and O’Connor, T.P. (2002).  Lipids: Nutritional significance.  In: Encyclopedia of Dairy Sciences.  H. Roginski, J.W. Fuquay and P.F. Fox, Editors.  Academic Press, London.  Pages 1622-1626

O’Connor, T.P. and O’Brien, N.M. (2002).  Lipids: Analytical methods.  In: Encyclopedia of Dairy Sciences.  H. Roginski, J.W. Fuquay and P.F. Fox, Editors.  Academic Press, London.  Pages 1583-1587.

O’Connor, T.P. and O’Brien, N.M. (2002).  Fat Replacers.  In: Encyclopedia of Dairy Sciences.  H. Roginski, J.W. Fuquay and P.F. Fox, Editors.  Academic Press, London.  Pages 1617-1622.

O’Connor, T.P. and O’Brien, N.M. (2000).  Nutritional aspects of cheese.  In: Fundamentals of Cheese Science.  P.F. Fox, T.P Guinee, T.M. Cogan and P.L.H. McSweeney, authors.  Aspen Publication, Maryland, USA.  Pages 504-513.

O'Connor, T.P. and O'Brien, N.M. (1995).  Lipid oxidation.  In: Advanced Dairy Chemistry, Volume 2.  Second Edition.  P.F. Fox, editor.  Chapman & Hall, London.  Pages 309-348.

O'Brien, N.M. (1993).  Nutrition and health.  In: Town and Gown: UCC Public Lecture Series 1992/93.  Cork University Press. Pages 1-9.

O'Connor, T.P. and O'Brien, N.M. (1991).  Significance of lipoxygenase in fruits and vegetables.  In: Food Enzymology.  P.F. Fox, editor. Elsevier Applied Science, London.  Pages 337-372

 

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